β-catenin-IN-2

Cas No.:	1458664-10-2
Chemical Name:	beta-Catenin-IN-2
Synonyms:	beta-catenin-IN-2;4-(6-Fluoro-1H-benzo[d]imidazol-2-yl)-N,N-dimethylaniline;β-catenin-IN-2
SMILES:	FC1C([H])=C([H])C2=C(C=1[H])N([H])C(C1C([H])=C([H])C(=C([H])C=1[H])N(C([H])([H])[H])C([H])([H])[H])=N2
Formula:	C15H14FN3
M.Wt:	255.2902
Purity:	>98%
Sotrage:	Powder-20°C3 years4°C2 yearsIn solvent-80°C6 months -20°C1 month

Description:	β-catenin-IN-2 is a potent β-catenin inhibitor, compound H1B1, extracted from patent US20150374662A1. β-catenin-IN-2 can be used for the study of colorectal cancer.
In Vitro:	β-catenin-IN-2 (10-40 μM) suppresses the transcriptional activity of the β-catenin/Tcf-4 in a dose-dependent manner in HCT116 cells[1].
References:	[1]. Ann Marie Bode, et al. Inhibitors of beta-catenin in treatment of colorectal cancer. Patent US20150374662A1.