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hDHODH-IN-8

  Cat. No.:  DC48820   Featured
Chemical Structure
2757405-31-3
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More than 5000 active chemicals with high quality for research!
Field of application
hDHODH-IN-8 is a potent inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 16 nM. hDHODH-IN-8 has potent antiproliferative activity and excellent aqueous solubility. hDHODH-IN-8 has the potential for the research of tumor disease, especially lymphoma.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2757405-31-3
Chemical Name: hDHODH-IN-8
Synonyms: Benzamide, 4-[(2-cyano-3-hydroxy-1-oxo-2-buten-1-yl)amino]-N-(2,6-difluorophenyl)-5-fluoro-2-[(1S)-2,2,2-trifluoro-1-methylethoxy]-;CompoundhDHODHIN8;hDHODH-IN-8
SMILES: C(NC1=C(F)C=CC=C1F)(=O)C1=CC(F)=C(NC(=O)C(C#N)=C(O)C)C=C1O[C@@H](C)C(F)(F)F
Formula: C21H15F6N3O4
M.Wt: 487.35
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_32721_DC48820
COA
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Cat. No. Product name Field of application
DC48820 hDHODH-IN-8 hDHODH-IN-8 is a potent inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 16 nM. hDHODH-IN-8 has potent antiproliferative activity and excellent aqueous solubility. hDHODH-IN-8 has the potential for the research of tumor disease, especially lymphoma.
DC28916 DHODH-IN-11 DHODH-IN-11 (Compound 14b) is a Leflunomide derivative and a weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03[1].
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