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Henagliflozin

  Cat. No.:  DC72660  
Chemical Structure
1623804-44-3
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More than 5000 active chemicals with high quality for research!
Field of application
Henagliflozin (SHR3824) is a potent selective sodium-glucose co-transporter 2 (SGLT2) inhibitor with the IC50 values of 2.38 and 4324 nM for human SGLT2 and SGLT1, respectively. Henagliflozin can be used in diabetes research.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1623804-44-3
Chemical Name: Henagliflozin
SMILES: O[C@H]1[C@@]2(C3=CC(CC4=CC(F)=C(C=C4)OCC)=C(C=C3)Cl)O[C@](CO2)([C@H]([C@@H]1O)O)CO
Formula: C22H24ClFO7
M.Wt: 454.87
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC39092 Ipragliflozin (L-Proline) Ipragliflozin L-Proline is an orally active and selective inhibitor of SGLT2 with IC50 of 7.38 nM, 6.73 nM and 5.64 nM for human SGLT2, rat SGLT2 and mouse SGLT2, respectively.
DC10765 LX-2761 LX2761 is a locally acting SGLT1 inhibitor that is highly potent in vitro and delays intestinal glucose absorption in vivo to improve glycemic control.
DC76802 rel-Licogliflozin rel-Licogliflozin is a relative configuration of Licogliflozin.
DC76801 Olorigliflozin Olorigliflozin is a sodium glucose co-transporter inhibitor with anti-hyperglycemic effects.
DC72660 Henagliflozin Henagliflozin (SHR3824) is a potent selective sodium-glucose co-transporter 2 (SGLT2) inhibitor with the IC50 values of 2.38 and 4324 nM for human SGLT2 and SGLT1, respectively. Henagliflozin can be used in diabetes research.
DC72659 Sergliflozin etabonate Sergliflozin etabonate (GW-869682X) is a potent and orally active sodium glucose cotransporter (SGLT2) inhibitor. Sergliflozin etabonate shows antidiabetic and antihyperglycemic effects. Sergliflozin etabonate significantly reduces non-fasting blood glucose levels in diabetic mice. Sergliflozin etabonate has the potential for the research of diabetes.
DC72658 Velagliflozin (proline) Velagliflozin proline is an oral sodium-glucose cotransporter 2 (SGLT2) inhibitor with antidiabetic activity. Velagliflozin proline reduces renal glucose reabsorption and stimulates glycosuria, which lowers blood sugar and insulin concentrations.
DC72657 Velagliflozin proline hydrate Velagliflozin proline hydrate is the clinical form of Velagliflozin. Velagliflozin is an oral sodium-glucose cotransporter 2 (SGLT2) inhibitor with antidiabetic activity. Velagliflozin reduces renal glucose reabsorption and stimulates glycosuria, which lowers blood sugar and insulin concentrations.
DC48201 SGLT1/2-IN-2 SGLT1/2-IN-2 demonstrates potent dual inhibitory activities (IC50 = 96 nM for SGLT1 and IC50 = 1.3 nM for SGLT2).
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