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| Cas No.: | 2094630-35-8 |
| Chemical Name: | PSB-16671 |
| Synonyms: | 3,3′-Methylenebis[5,7-difluoro-1H-indole];PSB-16671;3,3'-Methylenebis[5,7-difluoro-1H-indole] |
| SMILES: | C12=C(C(=CC(=C1)F)F)NC=C2CC1=CNC2C(F)=CC(F)=CC1=2 |
| Formula: | C17H10F4N2 |
| M.Wt: | 318.268317699432 |
| Purity: | >97% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Publication: | 1. Sarah J Mancini, et al. Sci Rep. 2019 Feb 12;9(1):1861 |
| Description: | PSB-16671 is a novel orthosteric and allosteric activator of GPR84, activates human GPR84 with EC50 of 41.3 nM in cAMP accumulation assays. PSB-16671 is selective versus related fatty acid receptors and the arylhydrocarbon receptor. PSB-16671 shows an EC50 of 5.47 uM in β-Arrestin assays, and allosteric KB value of 634 nM. |
| References: | 1. Sarah J Mancini, et al. Sci Rep. 2019 Feb 12;9(1):1861 |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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