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Home > Inhibitors & Agonists > Tyrosine Kinase > RET Tyrosine Kinase (c-RET)

RET-IN-14

Cat. No.: DC50275 Featured

Chemical Structure

2755843-62-8

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Field of application

RET-IN-14 (compound 49) is a potent RET inhibitor with IC50s of <0.51 nM, 9.3 nM, 1.3 nM, 9.2 nM, 15 nM for RET (WT), RET (G810R), RET (V804M), BTK and BTK (C481S), respectively. RET-IN-14 has the potential for tumors research

Chemicals Properties Biological activity COA & MSDS Related products Datasheet

Cas No.:	2755843-62-8
Chemical Name:	RET-IN-14
Synonyms:	RET-IN-14
SMILES:	NC1=C(C2C=CC(=CC=2)NC(=O)OC)C2=NCC3=CC(=CN=C3O[C@H](CNC(C3C=NN1C=3N2)=O)C)F \|t:15,&1:24\|
Formula:	C₂₄H₂₃FN₈O₄
M.Wt:	506.489027261734
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

Cat. No.	Product name	Field of application
DC50275	RET-IN-14	RET-IN-14 (compound 49) is a potent RET inhibitor with IC50s of <0.51 nM, 9.3 nM, 1.3 nM, 9.2 nM, 15 nM for RET (WT), RET (G810R), RET (V804M), BTK and BTK (C481S), respectively. RET-IN-14 has the potential for tumors research
DC10936	GSK3179106	GSK3179106 (GSK-3179106, GSK 3179106) is a potent, selective, first-in-class and gut-restricted with IC50 of 0.4 and 11 nM in the biochemical assay and cellular assay respectively.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.