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S6821

Cat. No.: DC73509 Featured

Chemical Structure

1119831-25-2

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Field of application

S6821 (S 6821) is a potent and selective antagonist of the bitter taste receptor TAS2R8, exhibiting an IC50 value of 21 nM. It demonstrates high selectivity across a panel of 16 TAS2Rs, effectively reduces the bitterness of coffee, and shows an excellent safety profile.

Chemicals Properties Biological activity COA & MSDS Related products Datasheet

Cas No.:	1119831-25-2
Chemical Name:	S6821
Formula:	C₁₉H₁₉N₅O₄
M.Wt:	381.392
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:	Fotsing JR, et al. J Med Chem. 2020 May 14;63(9):4957-4977.

Description:	S6821 (S 6821) is a potent and selective antagonist of the bitter taste receptor TAS2R8, exhibiting an IC50 value of 21 nM. It demonstrates high selectivity across a panel of 16 TAS2Rs, effectively reduces the bitterness of coffee, and shows an excellent safety profile.
References:	Fotsing JR, et al. J Med Chem. 2020 May 14;63(9):4957-4977.

MSDS

Cat. No.	Product name	Field of application
DC73509	S6821	S6821 (S 6821) is a potent and selective antagonist of the bitter taste receptor TAS2R8, exhibiting an IC50 value of 21 nM. It demonstrates high selectivity across a panel of 16 TAS2Rs, effectively reduces the bitterness of coffee, and shows an excellent safety profile.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.