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TFC 007

  Cat. No.:  DC71123   Featured
Chemical Structure
927878-49-7
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More than 5000 active chemicals with high quality for research!
Field of application
TFC-007, a selective hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, show high inhibitory activity against H-PGDS enzyme (IC50 value of 83 nM). TFC-007 can be used for composing H-PGDS degradation inducer PROTAC(H-PGDS)-1 (TFC-007 binds to H-PGDS, and Pomalidomide binds to cereblon).
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 927878-49-7
Chemical Name: TFC 007
Synonyms: 5-Pyrimidinecarboxamide,N-[4-[4-(4-morpholinylcarbonyl)-1-piperidinyl]phenyl]-2-phenoxy-;TFC 007;SCHEMBL23195705;CHEMBL4238186;TFC007;N-[4-[4-(morpholine-4-carbonyl)piperidin-1-yl]phenyl]-2-phenoxypyrimidine-5-carboxamide;BDBM50463722;EX-A3539;AKOS025142049;DA-68093;927878-49-7;HY-110167;NCGC00387231-01;CS-0033029;GTPL11392;TFC-007;N-[4-[4-(4-Morpholinylcarbonyl)-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide;N-(4-(4-(Morpholine-4-carbonyl)piperidin-1-yl)phenyl)-2-phenoxypyrimidine-5-carboxamide
SMILES: C1CN(CCC1C(=O)N2CCOCC2)C3=CC=C(C=C3)NC(=O)C4=CN=C(N=C4)OC5=CC=CC=C5
Formula: C27H29N5O4
M.Wt: 487.55026
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_35349_DC71123_927878-49-7
COA
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Cat. No. Product name Field of application
DC71123 TFC 007 TFC-007, a selective hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, show high inhibitory activity against H-PGDS enzyme (IC50 value of 83 nM). TFC-007 can be used for composing H-PGDS degradation inducer PROTAC(H-PGDS)-1 (TFC-007 binds to H-PGDS, and Pomalidomide binds to cereblon).
DC28168 FPL 62064 FLP 62064 is a potent 5-lipoxygenase (5-LOX) and COX-2 dual inhibitor. FLP 62064 has potently anti-inflammatory activity.
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