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TH470

  Cat. No.:  DC72319  
Chemical Structure
2834739-51-2
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More than 5000 active chemicals with high quality for research!
Field of application
TH470 is a highly selective LIMK1/2 (LIM kinase1/2) inhibitor (LIMK1 IC50=9.8 nM; LIMK2 IC50=13 nM), and can be used in orphan disease research.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2834739-51-2
Chemical Name: TH470
SMILES: CC(C(NC1=NC=C(S1)C(NCCN(C(C2=CC=C(C=C2)S(=O)(NC3=CC=CC=C3)=O)=O)CC4=CC=CC=C4)=O)=O)C
Formula: C30H31N5O5S2
M.Wt: 605.73
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_36770_DC72319_2834739-51-2
COA
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Cat. No. Product name Field of application
DC11706 R-10015 A potent, selective inhibitor of human LIMK1 with IC50 of 38 nM .
DC76210 MDI-114215 MDI-114215 (compound 85) is an allosteric LIMK1/2 dual inhibitor with good in vivo tolerance. MDI-114215 can inhibit cofilin phosphorylation in mouse brain region-induced pluripotent stem cells (iPSCs), which can be used for Fragile X Syndrome (FXS) research.
DC76209 LIJTF500025 LIJTF500025 is a potent and selective LIMK inhibitor, with pIC50 values of 6.77 and 7.03 for LIMK1 and LIMK2, respectively, as determined by NanoBRET. LIJTF500025 can be used for the research of cancer.
DC72319 TH470 TH470 is a highly selective LIMK1/2 (LIM kinase1/2) inhibitor (LIMK1 IC50=9.8 nM; LIMK2 IC50=13 nM), and can be used in orphan disease research.
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