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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC12350 | AMG-176 |
AMG-176 is a potent, selective and orally bioavailable MCL-1 inhibitor, with a Ki of 0.13 nM.
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| DC10964 | SW063058 |
SW063058 is a small molecule that selectively disrupt Beclin 1/Bcl-2 binding as compared to Bax/Bcl-2 and Bim/Bcl-2 binding and induces autophagic flux at concentrations with minimal cytotoxicity..
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| DC12279 | S55746 hydrochloride (BLC201 (hydrochloride)) |
S55746 hydrochloride is a potent, orally active and selective BCL-2 inhibitor, with Kis and Kds of 1.3 nM, 520 nM and 3.9 nM, 186 nM for BCL-2 and BCL-XL, respectively. S55746 hydrochloride has antitumor activity.
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| DC8264 | MM-41 |
MM41 is a quadruplex-interactive compound which binds strongly to the quadruplexes encoded in the promoter sequences of the BCL-2 and k-RAS genes.
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| DCAPI1148 | Gossypol |
Gossypol
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| DC10966 | BRD1991 |
BRD1991 is a small molecule that selectively disrupt Beclin 1/Bcl-2 binding as compared to Bax/Bcl-2 and Bim/Bcl-2 binding and induces autophagic flux at concentrations with minimal cytotoxicity..
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| DC2015 | AT-101 (AT101) |
AT-101 is a BH3 mimetic known to be a potent inhibitor of antiapoptotic Bcl-2 family members.
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| DC11613 | Mcl1-IN-26 |
A novel potent, selective Mcl-1 inhibitor with IC50 of <3 nM in FRET assays.
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| DCC-073 | Gossypol-acetic acid |
>98%,Standard References
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| DC9368 | (S)-Gossypol (acetic acid) |
(S)-Gossypol acetic acid is a inhibitor of Bcl-2, potently induce cell death in Jurkat cells overexpressing Bcl-2 (IC50, 18.1μM) or Bcl-xL (IC50, 22.9μM).
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