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| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC11800 | G1T38 dihydrochloride |
A novel, potent and selective inhibitor of CDK4/6 with biochemical IC50 of 1 nM and 2 nM for CDK4/cyclin D1 and CDK6/cyclin D3, respectively.
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| DC11799 | G1T38 |
A novel, potent and selective inhibitor of CDK4/6 with biochemical IC50 of 1 nM and 2 nM for CDK4/cyclin D1 and CDK6/cyclin D3, respectively.
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| DC11863 | CA224 |
A non-planar analogue of fascaplysin that selectively inhibits CDK4/cyclin D1 with IC50 of 5.5 uM.
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| DC11874 | CDK12 inhibitor E9 racemate |
A clinical analog of THZ1 and a selective, covalent CDK12 inhibitor that is not susceptible to ABC transporter-mediated drug efflux.
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| DC11873 | CDK12 inhibitor E9 R-isomer |
A clinical analog of THZ1 and a selective, covalent CDK12 inhibitor that is not susceptible to ABC transporter-mediated drug efflux.
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