Cat. No. | Product Name | Field of Application | Chemical Structure |
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DC8492 | Naloxegol Oxalate(NKTR-118) Featured |
Naloxegol is the first oral peripherally acting mu opioid receptor antagonists for opioid-induced constipation.
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DC8407 | Naloxone HCl Dihydrate Featured |
Naloxone HCl Dihydrate is an opioid inverse agonist drug used to counter the effects of opiate overdose.
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DC9790 | Nazartinib(EGF816) Featured |
Nazartinib(EGF816) is a novel covalent inhibitor of mutant-selective EGFR; overcomes T790M-mediated resistance in NSCLC.
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DC11406 | NBQX Featured |
NBQX is a potent aminomethylphosphonic acid receptor (AMPAR) antagonist with an IC50 of 0.7 ± 0.1 μM.
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DC10551 | Necrostatin 2 racemate Featured |
Necrostatin 2 is a potent necroptosis inhibitor with EC50 of 50 nM.
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DC8290 | (S)-PFI-2 HCl Featured |
Negative control of (R)-PFI 2 hydrochloride. Exhibits 500-fold lower activity in a SETD7 enzymatic assay (IC50 = 1 μM) compared to the active enantiomer.
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DC8823 | XY1 Featured |
Negative control of SGC 707. Exhibits >3000-fold lower potency (IC50 >100 μM) compared to the active analog.
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DC11469 | APD125(Nelotanserin) Featured |
Nelotanserin is a potent 5-HT2A inverse agonist, a moderately potent 5-HT2C partial inverse agonist and a weak 5-HT2B inverse agonist, with IC50s of 1.7, 79, 791 nM in IP accumulation assays, respectively.
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DC23087 | Neoandrographolide Featured |
Neoandrographolide has antiradical, anti-inflammatory,and hypolipidemic effects, it protects the cardiovascular without significant liver damage. Neoandrographolide as chemosensitizer in S-Jurkat and X chromosome-linked inhibitor of apoptosis protein (XIA
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DC5177 | Nepicastat HCl (SYN-117) Featured |
Nepicastat hydrochloride is a potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.
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DC11281 | NGI-1 (ML414) Featured |
NGI-1 (ML414) is a potent, cell-permeable oligosaccharyltransferase (OST) inhibitor with IC50 of 1.1 uM.
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DC11462 | NH-125 Featured |
NH125 is an imidazole that has potent antibacterial properties in drug-resistant bacteria.
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DC9758 | NI-57 Featured |
NI-57 is a potent inhibitor of the bromodomains of BRPF proteins that binds to BRPF1B, BRPF2, and BRPF3 with Kd values of 31, 108, and 408 nM, respectively, as determined by isothermal titration calorimetry.
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DC9796 | Nicainoprolhe(Nicainoprol) Featured |
Nicainoprolhe is an antiarrhythmic agent,a fast-sodiumchannel blocking drug (class Ib), also protected isolated rat hearts against reperfusion arrhythmias.
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DC7758 | Nimorazole Featured |
Nimorazole is a nitroimidazole anti-infective.
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DC9936 | NMS-P118 Featured |
NMS-P118 is a potent, orally available, and highly selective PARP-1 inhibitor with excellent ADME and pharmacokinetic profiles and high efficacy in vivo.
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DC10549 | Nomifensine maleate Featured |
Nomifensine maleate is a selective inhibitor of dopamine uptake, used in adult attention deficit disorder.
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DC8583 | Asenapine Maleate Featured |
Novel psychopharmacologic agent. Displays antagonist activity at 5-HT, dopamine, noradrenalin and histamine receptor subtypes (pKi values are 8.60, 8.40, 10.15, 9.75, 10.46, 8.84, 9.60, 9.94, 8.85, 8.90, 8.84, 9.38, 8.95, 8.93, 8.9, 9.49, 8.91, 9.00 and 8
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DC10453 | NP-118809 Featured |
NP-118809 is a N-type calcium channel blocker.
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DC9999 | NQ301 Featured |
NQ301 is a selective CD45 inhibitor (IC50 = 200 nM). Exhibits >200-fold selectivity for CD45 over six related protein tyrosine phosphatases.
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DC8787 | NQDI-1 Featured |
NQDI-1 is a specific inhibitor of ASK1 (IC50 = 3 μM; Ki = 500 nM) that demonstrates potent selectivity against various serine/threonine and tyrosine protein kinases.
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DC9734 | NS-1619 Featured |
NS-1619 is a selective MaxiKα (large conductance calcium activated potassium channel) activator.
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DC8183 | Paritaprevir(Veruprevir ABT-450) Featured |
NS3/4A protease inhibitor
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DC9608 | NS-304(Selexipag) Featured |
NS-304(Selexipag; ACT-293987) is an oral, selective prostacyclin receptor agonist for the treatment of pulmonary arterial hypertension.
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DC8725 | NSC 23766 Featured |
NSC 23766 is a specific inhibitor of the binding and activation of Rac GTPase.
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DC10603 | NSC 247030(SU5201) Featured |
NSC 247030 is a bioactive chemical.
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DC10599 | NSC 409012 Featured |
NSC 409012 is a bioactive chemical.
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DC33622 | CG347B Featured |
CG347B is a biochemical.
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DC10703 | NSC 6038 Featured |
NSC 6038 is a bioactive compound.
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DC10697 | NSC 80538 Featured |
NSC 80538 is a bioactive compound.
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