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Cat. No. Product Name Field of Application Chemical Structure
DC8492 Naloxegol Oxalate(NKTR-118) Featured
Naloxegol is the first oral peripherally acting mu opioid receptor antagonists for opioid-induced constipation.
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DC8407 Naloxone HCl Dihydrate Featured
Naloxone HCl Dihydrate is an opioid inverse agonist drug used to counter the effects of opiate overdose.
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DC9790 Nazartinib(EGF816) Featured
Nazartinib(EGF816) is a novel covalent inhibitor of mutant-selective EGFR; overcomes T790M-mediated resistance in NSCLC.
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DC11406 NBQX Featured
NBQX is a potent aminomethylphosphonic acid receptor (AMPAR) antagonist with an IC50 of 0.7 ± 0.1 μM.
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DC10551 Necrostatin 2 racemate Featured
Necrostatin 2 is a potent necroptosis inhibitor with EC50 of 50 nM.
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DC8290 (S)-PFI-2 HCl Featured
Negative control of (R)-PFI 2 hydrochloride. Exhibits 500-fold lower activity in a SETD7 enzymatic assay (IC50 = 1 μM) compared to the active enantiomer.
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DC8823 XY1 Featured
Negative control of SGC 707. Exhibits >3000-fold lower potency (IC50 >100 μM) compared to the active analog.
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DC11469 APD125(Nelotanserin) Featured
Nelotanserin is a potent 5-HT2A inverse agonist, a moderately potent 5-HT2C partial inverse agonist and a weak 5-HT2B inverse agonist, with IC50s of 1.7, 79, 791 nM in IP accumulation assays, respectively.
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DC23087 Neoandrographolide Featured
Neoandrographolide has antiradical, anti-inflammatory,and hypolipidemic effects, it protects the cardiovascular without significant liver damage. Neoandrographolide as chemosensitizer in S-Jurkat and X chromosome-linked inhibitor of apoptosis protein (XIA
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DC5177 Nepicastat HCl (SYN-117) Featured
Nepicastat hydrochloride is a potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.
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DC11281 NGI-1 (ML414) Featured
NGI-1 (ML414) is a potent, cell-permeable oligosaccharyltransferase (OST) inhibitor with IC50 of 1.1 uM.
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DC11462 NH-125 Featured
NH125 is an imidazole that has potent antibacterial properties in drug-resistant bacteria.
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DC9758 NI-57 Featured
NI-57 is a potent inhibitor of the bromodomains of BRPF proteins that binds to BRPF1B, BRPF2, and BRPF3 with Kd values of 31, 108, and 408 nM, respectively, as determined by isothermal titration calorimetry.
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DC9796 Nicainoprolhe(Nicainoprol) Featured
Nicainoprolhe is an antiarrhythmic agent,a fast-sodiumchannel blocking drug (class Ib), also protected isolated rat hearts against reperfusion arrhythmias.
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DC7758 Nimorazole Featured
Nimorazole is a nitroimidazole anti-infective.
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DC9936 NMS-P118 Featured
NMS-P118 is a potent, orally available, and highly selective PARP-1 inhibitor with excellent ADME and pharmacokinetic profiles and high efficacy in vivo.
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DC10549 Nomifensine maleate Featured
Nomifensine maleate is a selective inhibitor of dopamine uptake, used in adult attention deficit disorder.
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DC8583 Asenapine Maleate Featured
Novel psychopharmacologic agent. Displays antagonist activity at 5-HT, dopamine, noradrenalin and histamine receptor subtypes (pKi values are 8.60, 8.40, 10.15, 9.75, 10.46, 8.84, 9.60, 9.94, 8.85, 8.90, 8.84, 9.38, 8.95, 8.93, 8.9, 9.49, 8.91, 9.00 and 8
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DC10453 NP-118809 Featured
NP-118809 is a N-type calcium channel blocker.
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DC9999 NQ301 Featured
NQ301 is a selective CD45 inhibitor (IC50 = 200 nM). Exhibits >200-fold selectivity for CD45 over six related protein tyrosine phosphatases.
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DC8787 NQDI-1 Featured
NQDI-1 is a specific inhibitor of ASK1 (IC50 = 3 μM; Ki = 500 nM) that demonstrates potent selectivity against various serine/threonine and tyrosine protein kinases.
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DC9734 NS-1619 Featured
NS-1619 is a selective MaxiKα (large conductance calcium activated potassium channel) activator.
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DC8183 Paritaprevir(Veruprevir ABT-450) Featured
NS3/4A protease inhibitor
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DC9608 NS-304(Selexipag) Featured
NS-304(Selexipag; ACT-293987) is an oral, selective prostacyclin receptor agonist for the treatment of pulmonary arterial hypertension.
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DC8725 NSC 23766 Featured
NSC 23766 is a specific inhibitor of the binding and activation of Rac GTPase.
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DC10603 NSC 247030(SU5201) Featured
NSC 247030 is a bioactive chemical.
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DC10599 NSC 409012 Featured
NSC 409012 is a bioactive chemical.
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DC33622 CG347B Featured
CG347B is a biochemical.
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DC10703 NSC 6038 Featured
NSC 6038 is a bioactive compound.
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DC10697 NSC 80538 Featured
NSC 80538 is a bioactive compound.
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