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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DC81038 Methyl 7(E)-nonadecenoate
Methyl 7(E)-nonadecenoate is an unsaturated fatty acid methyl ester (FAME)。
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DC81037 Methyl 6(Z),9(Z),12(Z),15(Z),18(Z)-tetracosapentaenoate
Methyl 6(Z),9(Z),12(Z),15(Z),18(Z)-tetracosapentaenoate is an unsaturated fatty acid methyl ester (FAME)。
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DC81036 Methyl 5-aminovalerate hydrochloride
Methyl 5-aminovalerate hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
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DC81034 Methyl 16(Z)-pentacosenoate
Methyl 16(Z)-pentacosenoate is a fatty ester.
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DC81033 Methyl 10(Z),13(Z),16(Z)-docosatrienoate
Methyl 10(Z),13(Z),16(Z)-docosatrienoate is an unsaturated fatty acid methyl ester (FAME)。
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DC81032 Methoctramine
Methoctramine is a potent and cardioselectivity antagonist of M2 muscarinic receptor. Methoctramine can inhibit Muscarine-induced bradycardia in vivo. Methoctramine can be used in the study of cardiovascular diseases.
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DC81031 Methiocarb
Methiocarb (Mercaptodimethur) is an orally active carbamate insecticide. Methiocarb exerts dose-dependent toxic effects on onions. In addition to inhibiting acetylcholinesterase to induce cholinergic excitation, Methiocarb can induce lipid peroxidation in liver, kidney, brain and testicular tissues and alter reduced glutathione levels by generating ROS. Methiocarb can be used for agricultural pest control and research on oxidative stress-related cellular damage in mammals.
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DC81030 Methetoin
Methetoin is an anticonvulsant.
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DC81028 Menin-MLL-IN-37
Menin-MLL-IN-37 is an orally active Menin-MLL protein complex inhibitor with an IC50 of 820.50 nM. Menin-MLL-IN-37 disrupts the interaction between menin and MLL proteins. Menin-MLL-IN-37 induces differentiation of acute myeloid leukemia cells and selectively inhibits the proliferation of MLL-rearranged and DNMT3A/NPM1-mutant leukemia cells. Menin-MLL-IN-37 can be used for the research of acute myeloid leukemia (AML).
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DC81027 Menin-MLL-IN-36
Menin-MLL-IN-36 (compound 398) is an inhibitor of menin/MLL protein/protein interaction with an IC50 value of 0.043 μM in MEIS1 mRNA expression. Menin-MLL-IN-36 can be used in the research of cancer, myelodysplastic syndrome (MDS), myeloproliferative neoplasms (MPN), and diabetes.
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DC81026 Menin-MLL-IN-35
Menin-MLL-IN-35 (compound 286) is an inhibitor of menin/MLL protein/protein interaction with an IC50 value of 0.096 μM in MEIS1 mRNA expression. Menin-MLL-IN-35 can be used in the research of cancer, myelodysplastic syndrome (MDS), myeloproliferative neoplasms (MPN), and diabetes.
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DC81025 Memagal
Memagal is an AchE inhibitor (IC50 = 1.16 nM) and a NMDAR antagonist (Ki = 4.6 μM). Memagal inhibits the neurotoxicity induced by NMDA, with its IC50 value being 0.28 nM. Memagal can be used for research on Alzheimer's disease.
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DC81024 Mel56
Mel56 is a melanogenin analogue. Mel56 can promote the melanin production in human melanoma cells. Mel56 is cytotoxic to cancer cells and induces apoptosis in melanoma cells. Mel56 can be used for the study of melanoma.
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DC81023 MEK-IN-9
MEK-IN-9 (Compound 4-82) is a MEK inhibitor. MEK-IN-9 induces p15 and p27 protein. MEK-IN-9 can be used in the research of renal adenocarcinoma and colorectal cancer.
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DC81021 Meayamycin B
Meayamycin B ((+)-Meayamycin B) is a potent SF3B1 inhibitor. Meayamycin B upregulates the proapoptotic Mcl-1S and downregulates Mcl-1L at the pre-mRNA splicing level. Meayamycin B does not regulate the alternative splicing of Bcl-x. Meayamycin B and ABT-737 synergistically causes Apoptosis. Meayamycin B exhibits anticancer activity against non-small cell lung cancer.
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DC81020 ME 3407
ME-3407 (EF-4040) is a H+-K+-ATPase redistribution disruptor and myosin light chain kinase (MLCK) and protein kinase A inhibitor. ME-3407 blocks gastric acid secretion and aminopyrine accumulation by inhibiting microsomal-to-apical membrane redistribution of H+-K+-ATPase and suppressing MLCK-mediated myosin light chain phosphorylation. ME-3407 is promising for research of peptic ulcer.
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DC81019 MDL-20610
MDL-20610 is a potent antirhinovirus compound with an median plaque 50% inhibitory concentrations (IC1/2) of 0.003 µg/mL. MDL-20610 also exhibits activity against human, simian, and bovine rotaviruses and possesses variable enterovirus and paramyxovirus activity. MDL-20610 can be used for antiviral research.
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DC81018 MDL 72832 hydrochloride
MDL 72832 (hydrochloride) is a 2,3-dihydro-1,4-benzodioxane derivative and a 5-HT1a receptor ligand with high affinity for the 5-HT1a receptor.
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DC81017 MDL 19205
MDL 19205 is a cardiotonic agent with inotropic effect. MDL 19205 can be used for the research of cardiovascular disease, such as heart failure.
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DC81016 MDH2-IN-2
MDH2-IN-2 is an orally active MDH2 inhibitor with an IC50 of 5.9 μM. MDH2-IN-2 reduces the levels of senescence markers and senescence-associated secretory phenotype (SASP) factors in mammalian cell models. MDH2-IN-2 extends the lifespan and improves the healthspan of *Caenorhabditis elegans*. MDH2-IN-2 alleviates tissue senescence in aged mice, inhibits SASP factors, and restores liver and kidney functions. MDH2-IN-2 is applicable for senescence-related research.
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DC81014 MCH-1623
MCH-1623 is a nucleoside analog-derived, RNA-dependent RNA polymerase (RdRP) inhibitor. MCH-1623 interferes with viral RNA synthesis and exhibits broad-spectrum antiviral activity. MCH-1623 effectively inhibits the replication of vesicular stomatitis virus (VSV), influenza A virus (H1N1-PR8), human coronavirus OC43, human metapneumovirus (HMPV) and respiratory syncytial virus (RSV). Administered via inhalation, MCH-1623 exerts significant in vivo activity in mice, reducing pulmonary viral load and IL-6 levels, alleviating pulmonary tissue erythema, and significantly improving the survival rate of mice infected with lethal influenza virus. MCH-1623 can be used to investigate the infection mechanisms of various RNA viruses and for antiviral drug research.
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DC81013 MC-Gly-Gly-Phe-Gly-PAB-MMAE
MC-Gly-Gly-Phe-Gly-PAB-MMAE (Compound SMP-81641) is a control targeted linker-agent conjugate. MC-Gly-Gly-Phe-Gly-PAB-MMAE can be used in tumor research.
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DC81012 MC-Gly-Gly-Phe-Gly-cyclopropylacetic acid
MC-Gly-Gly-Phe-Gly-cyclopropylacetic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC81011 MC-GGFG-3-Methylenecyclobutyl
MC-GGFG-3-Methylenecyclobutyl (compound L-7B) is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC81010 Mc-Asn-Asn-E104
Mc-Asn-Asn-E104 is a conjugate of E104 and a legumain-cleavable linker, can be used for the synthesis of E104 ISACs.
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DC81009 Mc-Asn-Asn
Mc-Asn-Asn is a legumain cleavable linker for antibody-drug conjugates (ADCs) which couples the antibody element to the effecting compound. Mc-Asn-Asn can be used in the synthesis of ADCs.
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DC81008 Masoprocol tetrapivalate
Masoprocol tetrapivalate (Nordihydroguaiaretic acid tetrapivalate) is a catecholic butane metabolite and also a tyrosine kinase activity inhibitor of IGF-1R and EGFR. Masoprocol tetrapivalate regulates tyrosine kinase signaling pathways associated with cell proliferation. Masoprocol tetrapivalate can be used in the research of proliferative diseases, including malignant, precancerous or benign cancers, and solid tumors.
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DC81007 MARY15
MARY15 is a pyridinylpiperazine-based derivative of MARY1. MARY15 activates uncoupled mitochondrial respiration and upregulates p-AKT (S473) phosphorylation in renal proximal tubule cells.
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DC81006 Marpinersen
Marpinersen, an antisense oligonucleotide, is an ataxin-2 synthesis reducer. It is used for the study of amyotrophic lateral sclerosis.
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DC81005 Mardepodect precursor
Mardepodect precursor is the precursor of Mardepodect. Mardepodect precursor. Mardepodect is a potent, selective orally active, and brain-penetrant PDE10A inhibitor with an IC50 of 0.37 nM, with >1000-fold selectivity over other PDEs.
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