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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DC48636 Carbonic anhydrase inhibitor 3
Carbonic anhydrase inhibitor 3 (compound 11g) is a carbonic anhydrase II inhibitor. Carbonic anhydrase inhibitor 3 reduces the intraocular pressure in glaucomatous rabbits.
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DC48635 R110
R110 is a potent, competitive inhibitor of MIF2 tautomerase with an IC50 of 15 μM. R110 has the potential for the research of cancer diseases.
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DC48633 NLRP3/AIM2-IN-1
NLRP3/AIM2-IN-1 is a thermal sepsis inhibitor with an < b > IC < sub > 50 < / sub > < / b > value of 3.136 ± 0.7667 μ M.
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DC48632 NLRP3/AIM2-IN-2
NLRP3 / aim2-in-2 is a new potent inhibitor with different species-specific effects on NLRP3 and aim2 inflammasome dependent cell death. Its < b > IC < sub > 50 < / sub > < / b > value is 0.2392 ± 0.0233 μ M。
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DC48631 Guaiacol Carbonate
Guaiacol Carbonate acts as an expectorant by virtue of a reflex from the stomach by way of the afferent gastric nerves to the medullary centres and thenperipherally again to the respiratory tract.
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DC48630 HG122
HG122 promotes androgen receptor (AR) degradation through the proteasome pathway inhibiting the castration-resistant prostate cancer.
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DC48629 Mycobactin-IN-1
Mycobactin-IN-1 (compound 44), a pyrazoline analogue, is a mycobactin biosynthesis inhibitor against mycobacteria. Mycobactin-IN-1 binds to salicyl-AMP ligase (MbtA), a key enzyme in the mycobactin biosynthetic pathway.
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DC48628 Mycobactin-IN-2
Mycobactin-IN-2 (compound 49) is a mycobactin biosynthesis inhibitor against mycobacteria. Mycobactin-IN-2 binds to salicyl-AMP ligase (MbtA), a key enzyme in the mycobactin biosynthetic pathway.
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DC48627 (+)-Butin
(+)-Butin is the R enantiomer of Butin. Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities.
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DC48626 Djalonensone
Djalonensone shows markedly DPPH radical scavenging activities.
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DC48625 5-(3-hydroxyphenyl)-5-phenylhydantoin
5-(3-hydroxyphenyl)-5-phenylhydantoin, is a metabolite of anti-seizure agent Phenytoin.
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DC48624 Viridicatin
Viridicatin is a fungal metabolite from Penicillium species. Viridicatin shows slight in vitro antibiotic activity against Mycobacterium tuberculosis.
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DC48623 FLT3-IN-10
FLT3-IN-10 (compound 7c) is a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3). FLT3-IN-10 has the potential for the treatment of FLT3-mutated acute myeloid leukemia (AML).
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DC48622 2-Hydroxyemodin
2-Hydroxyemodin is an active metabolite of emodin in the hepatic microsomes. Emodin is an anthraquinone present in fungal metabolites and constituent of rhubarb. 2-Hydroxyemodin proves to be mutagenic to Salmonella typhimurium TA1537 in the absence of activation system.
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DC48621 NS3694
NS3694, a diarylurea compound, is an apoptosome inhibitor. NS3694 inhibits apoptosome formation and caspase activation.
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DC48620 MR 409
MR 409 is a selected growth hormone-releasing hormone (GHRH) agonist. MR 409 has remarkable neuroprotective effects through enhancing endogenous neurogenesis in cerebral ischemic mice. MR 409 also inhibits the in vivo growth of lung cancer.
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DC48619 Colistin adjuvant-2
Colistin adjuvant-2 is a colistin adjuvant, shows increased colistin potentiation activity against Gram-negative bacteria.
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DC48617 Sodium tetradecyl sulfate
Sodium tetradecyl sulfate (Tergitol 4) is a sclerosing agent used for the research of varicose veins.
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DC48616 Tetradecyl sulfate sodium
Tetradecyl sulfate sodium, a detergent sclerosant, is widely used agent for esophageal varices and varicose veins.
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DC48614 Pentetic acid
Pentetic acid is a compound used to construct magnetic adsorbent, which can simultaneously remove heavy metal and dye from complex wastewater.
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DC48613 Palitantin
Palitantin ((±)-Palitantin), a metabolite of Penicillium frequentans on Leishmania brasiliensis, has antiprotozoal effect against Leishmania brasiliensis.
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DC48612 Isoamyl 4-(dimethylamino)benzoate
Isoamyl 4-(dimethylamino)benzoate can be used for the synthesis of inclusion complex (isoamyl4-(Dimethylamino)benzoate with sulfobutylether-β-cyclodextrin).
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DC48611 (R)-Preclamol
(R)-Preclamol is a dopamine (DA) agonist with autoreceptor as well as postsynaptic receptor stimulatory properties. (R)-Preclamol inhibits the locomotor activity of mice and rats in low doses.
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DC48610 Clonostachydiol
Clonostachydiol is an anthelmintic macrodiolide from the fungus Clonostachys cylindrospora (strain FH-A 6607).
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DC48609 Asperaculane B
Asperaculane B is a fungal metabolite against P. falciparum transmission with an IC50 of 7.89 µM. Asperaculane B also inhibits the development of asexual P. falciparum with IC50 of 3 µM, and it is nontoxic to human cells.
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DC48608 Aculene D
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations.
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DC48606 UCSF686
UCSF686 is a probe with which to study the function of the 5-HT5AR. UCSF686 loses affinity at 5-HT5AR (>10 000 nM) but not at 5-HT1AR, 5-HT2BR, and 5-HT7R. UCSF686 controls for off-target effects.
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DC48605 Sulfo-NHS-Biotin sodium
Sulfo-NHS-Biotin (sodium) stongly label single SDS-2ME soluble cuticular protein.
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DC48604 Cefetamet
Cefetamet is a cephalosporin antibiotic. Cefetamet has the potential for the research of both upper and lower community-acquired respiratory tract infections.
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DC48603 Chaetosemin J
Chaetosemin J, an antifungal metabolite, exhibits inhibitory activity against plant pathogenic fungi Botrytis cinerea, Alternaria solani, Magnaporthe oryzae, and Gibberella saubinettii, with MIC values ranging from 12.5-25 μM.
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