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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DC46624 HCV-IN-29
HCV-IN-29 is a hepatitis C virus (HCV) inhibitor exacted from patent US8329159B2, compound 1e.
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DC46623 Guanosine triphosphate
Guanosine triphosphate is a native nucleotide. The derivatives of GTP may be used as specific inhibitors against COVID-19.
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DC46622 Lycopsamine N-oxide
Lycopsamine N-oxide, an N-oxide of Lycopsamine which is a pyrrolizidine alkaloid, can be found in honey and bee pollen.
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DC46621 Jacobine N-oxide
Jacobine N-oxide, an N-oxide of Jacobine which is a pyrrolizidine alkaloid, can be found in Senecio hybrids that has thrips resistance.
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DC46620 Erucifoline
Erucifoline is a pyrrolizidine alkaloid that can be found in the aerial parts of Senecio aquaticus.
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DC46619 1-Methoxycarbonyl-β-carboline
1-Methoxycarbonyl-β-carboline is a natural alkaloid.
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DC46617 Lyciumin B
Lyciumin B is a cyclic peptide isolated from Lysium chinense.
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DC46616 Piscidin-1 (22-42)
Piscidin-1 (22-42) is a highly potent, multi-functional Antimicrobial Peptide (AMP) produced by Orange-spotted grouper (Epinephelus coioides). Piscidin-1 (22-42) has many functional usages including antibacterial, antifungal, antiviral, antiprotozoal, anticancer, immunomodulatory, and wound healing properties.
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DC46615 Potassium acetate
Potassium acetate is a potassium salt employed to replenish electrolytes, for restoration of water-electrolyte balance. Potassium acetate can employ in DNA and protein purification. Potassium acetate has been used to prepare neutralizing solution for alkaline lysis of bacteria.
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DC46614 PSMα3 TFA
PSMα3 TFA is a peptide for manipulating DCs to become tolerogenic for DC vaccination strategies. PSMα3 TFA penetrates and modulates human monocyte-derived DCs by altering the TLR2- or TLR4-induced maturation, inhibiting pro- and anti-inflammatory cytokine production and reducing antigen uptake. PSMα3 TFA is an important toxin released by the most virulent strains of methicillin-resistant Staphylococcus aureus (MRSA).
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DC46613 Interphotoreceptor retinoid-binding protein(668-687) TFA
Interphotoreceptor retinoid-binding protein(668-687) TFA, the amino acid residues 668 to 687 of human interphotoreceptor retinoid binding protein (IRBP), induces uveitis.
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DC46612 InsB (9-23)
InsB (9-23) is an insulin B-chain peptide that binds to a class II histocompatibility complex (MHC) allele called I-Ag7. InsB (9-23) can be used to treat a number of autoimmune related diseases like Type 1 diabetes.
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DC46611 HIF-1 alpha (556-574) (TFA)
HIF-1 alpha (556-574) TFA is a short hypoxia-inducible factor-1 (HIF-1) 19 residues fragment. HIF-1 functions as master regulator of response to oxygen homeostasis.
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DC46610 Bacterial Sortase Substrate III, Abz/DNP
Bacterial Sortase Substrate III, Abz/DNP is an internally quenched fluorescent peptide substrate. Staphylococcus aureus transpeptidase sortase A (SrtA) reacts with its native substrate Bacterial Sortase Substrate III, Abz/DNP, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Cleavage of this substrate can be monitored at Ex/Em=320 nm/420 nm.
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DC46609 Cyclotraxin B TFA
Cyclotraxin B TFA, a cyclic peptide, is a highly potent and selective TrkB inhibitor without altering the binding of BDNF. Cyclotraxin B TFA non-competitively inhibits BDNF-induced TrkB activity with an IC50  of  0.30 nM. Cyclotraxin B TFA can crosse the blood-brain-barrier and has analgesic and anxiolytic-like behavioral effects.
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DC46608 Compstatin control peptide TFA
Compstatin control peptide TFA is a complement inhibitor that binds and inhibits cleavage of complement C3.
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DC46607 [pSer2, pSer5, pSer7]-CTD TFA
[pSer2, pSer5, pSer7]-CTD (TFA), a substrate for CDK7 (cyclin dependent protein kinase), is a phosphorylated polypeptide at ser2, ser5 and ser7 sites of RNA polymerase II carboxy-terminal domain (CTD).
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DC46606 H-Ala-Ala-Tyr-OH TFA
H-Ala-Ala-Tyr-OH TFA can be synthesized mutant peptides.
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DC46605 Z-VRPR-FMK TFA
Z-VRPR-FMK (TFA) (VRPR), a tetrapeptide, is a selective and irreversible MALT1 (Mucosa-associated lymphoid tissue lymphoma translocation protein 1) inhibitor. Z-VRPR-FMK (TFA) can protect against influenza A virus (IAV) infection.
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DC46603 Methylamino-PEG3-benzyl
Methylamino-PEG3-benzyl is an amino PEG linker.
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DC46602 GA-PEG5-bromide
GA-PEG5-bromide is a probe used for molecular labeling.
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DC46601 Cy7-YNE
Cy7-YNE is a fluorescence labeling agent (Ex=700-770 nm,Em=790 nm). Cyanine dyes are used to label proteins, antibodies, and peptides.
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DC46600 CY7-N3
CY7-N3 (Sulfo-Cyanine7-N3) is a water-soluble NIR dye azide for Click Chemistry.
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DC46599 Cycloguanil D6
Cycloguanil D6 is the deuterium labeled Cycloguanil, which is a dihydrofolate reductase inhibitor.
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DC46598 Obestatin(human) TFA
Obestatin(human) TFA is an endogenous peptide derived from the same prepropeptide as ghrelin. Obestatin(human) suppresses food intake and reduce body weight-gain in rats.
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DC46597 ELA-32(human) TFA
ELA-32(human) TFA is a potent, high affinity apelin receptor agonist (IC50=0.27 nM; Kd=0.51 nM). ELA-32(human) TFA exhibits no binding GPR15 and GPR25. ELA-32(human) TFA activates the PI3K/AKT pathway and promotes self-renewal of hESCs via cell-cycle progression and protein translation. ELA-32(human) TFA also potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage. ELA-32(human) TFA stimulates angiogenesis in HUVEC cells.
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DC46596 ELA-11(human) TFA
ELA-11(human) TFA is a high affinity apelin receptor agonist (Ki=14 nM). ELA-11(human) TFA is a bioactive fragment of ELA-32. ELA-11(human) TFA inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro.
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DC46595 BigLEN(mouse) TFA
BigLEN(mouse) TFA is a GPR171 agonist. BigLEN(mouse) TFA is a proSAAS-derived neuropeptide. BigLEN(mouse) TFA regulates food intake in mice. BigLEN(mouse) inhibits the release of glutamate onto parvocellular neurons of the paraventricular nucleus in a process dependent upon activation of postsynaptic G proteins.
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DC46594 SAHM1 TFA
SAHM1 TFA is a Notch pathway inhibitor. SAHM1 TFA stabilizes hydrocarbon-stapled alpha helical peptide. SAHM1 TFA targets the protein-protein interface and prevents Notch complex assembly.
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DC46593 NoxA1ds TFA
NoxA1ds TFA is a potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50=20 nM). NoxA1ds TFA exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. NoxA1ds TFA inhibits NOX1-derived O2- production in HT-29 human colon cancer cells. NoxA1ds TFA attenuates VEGF-induced human pulmonary artery endothelial cell migration under hypoxic conditions in vitro.
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