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Inhibitors & Agonists

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Cat. No. Product Name Field of Application Chemical Structure
DC40661 4,6-Dichloroguaiacol
4,6-Dichloroguaiacol induces biochemical and morphological changes in human peripheral blood lymphocytes in vitro.
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DC40660 5,6-Dichlorovanillin
5,6-Dichlorovanillin is a product upon chlorination to afford 4,5,6-trichloroguaiacol, together with tetrachloroguaiacol and the unreacted starting materials.
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DC40659 3,4,5-Trichlorosyringol
3,4,5-Trichlorosyringol is a chlorophenolic compound synthetised by chlorination of syringol in carbon disulphide (CS2).
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DC40658 Tetrachloroveratrole
Tetrachloroveratrole is one of the biodegradation products of bacterial O-methylation of Tri- and Tetra chloroguaiacols. The Tri- and Tetra chloroguaiacols are formed during bleaching of wood pulp in the paper manufacturing industry.
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DC40657 3,4,5-Trichloroveratrole
3,4,5-Trichloroveratrole is one of the biodegradation products of bacterial O-methylation of Tri- and Tetra chloroguaiacols. The Tri- and Tetra chloroguaiacols are formed during bleaching of wood pulp in the paper manufacturing industry.
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DC40655 Tetrachloroguaiacol
Tetrachloroguaiacol is the major chlorinated phenol produced during chlorine bleaching of wood pulp.
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DC40654 3,4,5-Trichloroguaiacol
3,4,5-Trichloroguaiacol is a phenolic compound occurring in effluents from bleached kraft pulp mills.
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DC40653 4,5,6-Trichloroguaiacol
4,5,6-Trichloroguaiacol is a phenolic compound occurring in effluents from bleached kraft pulp mills.
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DC40652 4,5-Dichloroguaiacol
4,5-Dichloroguaiacol is the major component of chlorinated phenol。
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DC40651 3,4,5-Trichlorocatechol
3,4,5-Trichlorocatechol is a catechol derivative of pentachlorophenol and induces oxidative DNA lesions.
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DC40650 4-Chlorocatechol
4-Chlorocatechol is a major degradation product of 4-chloro-2-aminophenol (4C2AP). 4-Chlorocatechol is also a substrate for catechol 1,2-dioxygenases and chlorocatechol dioxygenase.
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DC40648 12-Chlorodehydroabietic acid
12-Chlorodehydroabietic acid is a chlorinated resin acid.
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DC40647 Neoabietic acid
Neoabietic acid is an abietic-type acid isolated from the oleoresin and rosin of Pinus palustris. Neoabietic acid is highly susceptible to mineral acid. Neoabietic acid has antibacterial activity in vitro.
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DC40646 Senecivernine
Senecivernine, a pyrrolizidine alkaloid isolated from Senecio species, exhibits a weakly mutagenic activity.
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DC40644 Fulvine
Fulvine is a pyrrolizidine alkaloid isolated from the seeds of Crotalaria fulva. Fulvine is hepatotoxic and can be used to induce hypertensive pulmonary vascular disease in vivo.
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DC40643 4-Formylaminoantipyrine
4-Formylaminoantipyrine?is an excreted metabolite of?aminophenazone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic effects in vivo.
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DC40642 1,1,1,3,10,11-Hexachloroundecane
1,1,1,3,10,11-Hexachloroundecane is a kind of polychlorinated alkane (PCA) that has a long carbon chain length.
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DC40630 Aminohexylgeldanamycin
Aminohexylgeldanamycin (AHGDM), a Geldanamycin derivative, is a potent HSP90 inhibitor. Aminohexylgeldanamycin shows antiangiogenic and antitumor activities.
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DC40629 17-AEP-GA
17-AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion. ADCs Toxin.
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DC40627 mGluR2 antagonist 1
mGluR2 antagonist 1 is a highly potent, orally bioavailable and selective class of mGluR2 negative allosteric modulator (IC50 of 9 nM) with excellent brain permeability.
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DC40626 RET-IN-3
RET-IN-3 (compound 34) is a selective RETV804M kinase inhibitor, with an IC50 of 19 nM.
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DC40625 WF-47-JS03
WF-47-JS03 is a potent and selective RET kinase inhibitor with IC50s of 1.7 nM and 5.3 nM for KIF5B-RET transfected Ba/F3 cells and CCDC6-RET transfected LC-2/ad lung cancer cells, respectively. WF-47-JS03 demonstrates >500-fold selectivity against kinase insert domain receptor (KDR). Effective brain penetration.
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DC40611 PA-Nic TFA
PA-Nic TFA is a photoactivatable nicotine, whcih can be photolyzed with ~405 nm laser flashes to efficiently release nicotine.
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DC40610 O-2050
O-2050 is a high affinity cannabinoid CB1?receptor silent antagonist. O-2050 also acts as a partial agonist in inhibiting forksolin-induced cyclic AMP stimulation (EC50=40.4 nM). O-2050 antagonizes effects of?CP-55940 in vitro.
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DC40609 PA-8
PA-8 is a potent, selective and orally active PACAP type I (PAC1) receptor antagonist. PA-8 inhibits the phosphorylation of CREB induced by PACAP in PAC1-, but not VPAC1- or VPAC2-receptor. PA-8 also inhibits PACAP-induced cAMP elevation with an IC50 of 2 nM.
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DC40588 Mabuterol-D9
Mabuterol-D9 is a deuterium labeled Mabuterol. Mabuterol is an agonist of the β2-adrenergic receptor.
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DC40587 Daclatasvir Impurity C
Daclatasvir Impurity C is the impurity of Daclatasvir. Daclatasvir is a potent HCV NS5A protein inhibitor.
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DC40586 Daclatasvir Impurity B
Daclatasvir Impurity B is the impurity of Daclatasvir. Daclatasvir is a potent HCV NS5A protein inhibitor.
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DC40585 Monodes(N-carboxymethyl)valine Daclatasvir
Monodes(N-carboxymethyl)valine Daclatasvir (Daclatasvir Impurity A) is the main degradation product of Daclatasvir. Daclatasvir is a potent HCV NS5A protein inhibitor.
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DC40584 Oseltamivir acid D3
Oseltamivir acid D3 (GS 4071 D3) is a deuterium labeled Oseltamivir acid. Oseltamivir acid, the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses.
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