WAY-267464 (WAY267464) is a potent, selective, non-peptide oxytocin receptor agonist with Ki of 58.4 nM, >100-fold selectivity over V1a, V2, V1b receptors.

WAY-196025 is a potent, selective, and orally active inhibitor of cPLA2α with IC50 of 12 nM for LTB4 inhibition.

W-212393 (MT-7716 free base) is a highly potent, brain penetrant ORL1 receptor (NOP receptor) agonist with Ki of 0.76 and 0.50  nM for rat and human ORL1 receptors, respectively.

VX-984 is a potent DNA-PKinhibitor.

VX-148 is a potent, uncompetitive, orally bioavailable IMPDH inhibitor with Ki of 6 nM against IMPDH type II enzyme.

VU-WS113 is a potent inhibitor of Wnt signaling with EC50 of 80 nM that selectively potentiates CK1α kinase activity..

VUT-MK142 is a cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes, shows superior cardiomyogenic activity over cardiogenol C.

VUF15000 (VUF-15000) is the first photoswitchable GPCR Histamine H3 receptor agonist (pKi=8.42), displays >300-fold selective for hH3R over hH1R and hH2R.

VUF-10214 is a potent, selective histamine H4 receptor (H4R) ligand with pKi of 7.4, shows anti-inflammatory properties in vitro..

VU6009003 is a potent, selective, CNS penetrant mAChR M4 positive allosteric modulator with EC50 of 197 nM and 437 nM for human and rat M4, respectively..

VU6007678 is a potent, subtype selective, CNS penetrant M5 mAChR positive allosteric modulator (PAM) with EC50 of 41 nM.

VU6007477 is a novel potent, selective, CNS penetrant M1 positive allosteric modulator (PAM) with EC50 of 230 nM, 93% ACh max with minimal M1 agonist activity.

VU6004256 (VU 6004256) is a highly potent, selective M1 muscarinic acetylcholine receptor (mAChR) positive allosteric modulator with EC50 of 155 nM (mouse M1), significant selectivity over M2-M5 (EC50>30 uM).

VU6001376 (VU 6001376, VU-6001376) is a potent, selective, positive allosteric modulator of mGlu4 with EC50 of 28 nM, 49% Glu Max, shows no activity against other 7 mGlu receptors.

VU6001221 is a potent choline transporter (CHT) inhibitor with IC50 of 270 nM.

VU0810464 (VU 0810464, VU464) is a selective neuronal GIRK channels activator, displays nanomolar potency for GIRK1/2 (EC50=163 nM) and improved brain penetration.

VU0486846 is a novel potent, highly selective M1 mAChR positive allosteric modulation (PAM) with EC50 of 0.31 uM.

VU0481443 (ML380) is a potent, selective and CNS penetrant M5 positive allosteric modulator (PAM) with EC50 of 190 nM for hM5.

VU0467485 (VU-0467485, AZ13713945) is potent, selective, and orally bioavailable muscarinic acetylcholine receptor 4 (M4) positive allosteric modulator with EC50 of 78.8 nM (hM4).

VU0467154 (VU 0467154) is a potent, selective M4 mAChR positive allosteric modulator with EC50 of 17.7 nM.

VU0453595 (VU453595) is a potent, selective M1 positive allosteric modulator (PAM) with EC50 of 3.2 uM (rM1).

VU0422288 is a potent, selective, CNS-penetrant pan-Group III mGlu positive allosteric modulator with IC50 of 110/146/130 nM for mGlu8/7/4, respectively, displays >30-fold selectivity over groups I and II mGlus (mGlu1/2/3/5/6)..

VU0418506 (VU 0418506) is a potent and selective mGlu4 positive allosteric modulator (PAM) with EC50 of 68 nM (hmGlu4).

VU0410425 is a potent, selective negative allosteric modulator of rat mGluR1 with IC50 of 140 nM, inactive at human mGluR1 (IC50>30 uM)..

VU0400195 (ML 182) is a potent, selective, brain penetrant and orally active positive allosteric modulator of mGluR4 with EC50 of 291 nM and 376 nM for human and rat mGluR4, respectively.

VU0152099 is a potent, selective, CNS-penetrant positive allosteric modulator of M4 mAChR with EC50 of 403 nM.

VU 6008667 is a potent, highly selective M5 negative allosteric modulator with IC50 of 1.2 uM.

VU 10010 is a selective, allosteric potentiator of M4 mAChR (EC50=33 and 0.7 nM for ACh in the absence and presence of VU10010 respectively), has no activity at other mAChR subtypes.

VU 0650786 (VU0650786, VU-0650786) is a potent and selective, CNS penetrant mGlu3 negative allosteric modulator with IC50 of 392 nM, with no significant activity against other mGlus (IC50>10 uM).

VU 0240551 is a potent, selecticve inhibitor of the neuronal K-Cl cotransporter KCC2 with IC50 of 568 nM in K+ uptake assay in KCC2-overexpressing cells.