Fhit-IN-15 is a potent, competitive, reversible inhibitor of the enzymatic activity of tumor suppressor Fhit with IC50 of 49 nM, shows cytotoxicity in HEK293T cells..

FGI-104 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV (EC90=330 nM, ZEBOV) and MARV (EC50=2.5 uM, MARV-Ci67).

FGI-103 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV (EC90=330 nM, ZEBOV) and MARV (EC50=2.5 uM, MARV-Ci67).

FGFR4-IN-1 is a potent inhibiotr of FGFR4 with IC50 of 0.7 nM.

FFN-206 is an excellent VMAT2 (vesicular monoamine transporter 2) substrate capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling

FF-10502 (FF-10502-01) is a pyrimidine nucleoside antimetabolite that shows growth inhibition of pancreatic cancer cell lines with IC50 of 60-330 nM.

FF-10501-01 is a potent, selective and orally available IMPDH inhibitor.

Fesoterodine (PF-00695838) is a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties.

Fesoterodine (PF-00695838) is a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties.

Feretoside, a phenolic compound extracted from the barks of E. ulmoides, is a HSP inducer which act as cytoprotective agent.

FEN1-IN-C20 is an N‐hydroxyl urea derivative that specifically inhibits flap endonuclease 1 (FEN1) activity with IC50 of 3 nM.

FEN1-IN-1 is a potent, selective Flap Endonuclease-1 (FEN1) inhibitor with IC50 of 11 nM.

FD-44 (FD44, NCS-1-Ric8a inhibitor FD44) is a potent inhibitor of the NCS-1/Ric8a interaction, interferes with NCS-1/Ric8a binding, and restores normal synapse number and associative learning in a Drosophila FXS model.

FCPR03 is a novel potent, selective PDE4 inhibitor with IC50 of 60, 31 and 47 nM for PDE4CAT (PDE4 catalytic domain), PDE4B1 and PDE4D7, respectively.

FAS-IN-1 is a potent inhibitor of fatty acid synthase (FAS) wtih IC50 of 10 nM..

Faropenem is an orally active beta-lactam antibiotic with broad-spectrum antibacterial activity against many gram-positive and gram-negative aerobes and anaerobes.

Faropenem daloxate is the first oral penem in a new class of beta-lactam antibiotics.

Famitinib (SHR1020) is a structural analogue of sunitinib, novel and potent multi-targeted RTK inhibitor, including c-Kit, VEGFR2/3, PDGFRβ, FLT-1/3 receptor and c-RET.

FAK inhibitor 5 is the first highly potent, selective irreversible inhibitor of the FAK kinase with IC50 of 0.6 nM.

Fadaltran is a α2-adrenoreceptor antagonist..

Factor D inhibitor 7 is a potent and selective, orally bioavailable inhibitor of Factor D with IC50 of 50 nM.

Factor D inhibitor 6 is a potent and selective, orally bioavailable inhibitor of Factor D with IC50 of 30 nM.

EZH2-IN-3 is a highly selective small molecule inhibitor of EZH2 and EZH1 with IC50 of 21/197/213 nM for wt EZH2/EZH2 Y641N/wt EZH1 respectively.

Exenatide (Exendin-4) is a 39-aa peptide, highly potent, long-acting glucagon-like peptide-1 receptor (GLP-1) agonist with IC50 of 3.22 nM.

EXEL-0346 (EXEL0346) is a novel potent, orally active Glucosylceramide synthase (GCS) inhibitor with IC50 of 2 nM.

Evans Blue is a potent inhibitor of the uptake of L-glutamate into synaptic vesicles, also an AMPA/kainate receptor antagonist

Eurycomanone could increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis.

Etriciguat is a novel potent, selective, orally available soluble guanylate cyclase (sGC) stimulator..

Etretinate is an oral aromatic retinoid acid which is effective in psoriasis and other dermatological syndromes.

Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) of human immunodeficiency virus type 1 (HIV-1).