A cell-permeable small molecule inhibitor of Fumarase (fumarate hydratase), an enzyme of the tricarboxylic acid cycle (TCA cycle).

A cell-permeable mitochondrial calcium uptake inhibitor that binds to mitochondria with high affinity (Kd=340 pM) and blocks Ca2+ uptake into mitochondria in vitro with IC50 of 184 pM.

A cell-permeable inhibitor of the KIX-KID interaction and CREB-mediated gene transcription (IC50=2.26 uM).

A cell permeable CBP bromodomain inhibitor with Kd of 19 uM.

A cell permeable CBP bromodomain inhibitor with Kd of 19 uM.

A cell differentiation inducer that inhibits activation of NF-κB function, Akt and ERK/MAPK cascade.

A cardioselective beta blocker for the treatment of hypertension and arrhythmias..

A carboxylic acid amide (CAA) fungicide..

A carbamate insecticide that acts as a fast-acting cholinesterase inhibitor..

A carbamate insecticide that acts as a fast-acting cholinesterase inhibitor..

A CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively).

A broad-spectrum RTKs inhibitor with IC50 ranging from 2 to 50 nM for VEGFR-1, VEGFR-2, PDGFRs, KIT, FLT3, and CSF1R/FMS.

A broadly selective, potent, ATP-competitive Akt kinase inhibitor with IC50 of 0.5 nM(biochemical assay), and 0.31 nM (cell function assay).

A bis-anthracycline and melanoma selective agent that demonstrates anti-melanoma activity at low nanomolar concentrations.

A biologically active natural product isolated from Streptomyces that has been shown to inhibit tumor cell migration.

A bioactive, specific small molecule that targets RNA of the expanded repeat (r(GGGGCC)exp) with Kd of 9.7 uM.

A benzophenone tetracarboxylic derivative that can improve the activity and stability of alkaline phosphatases from psychrophilic and mesophilic organisms..

A benzofuran class inhibitor of M. tuberculosis Pks13 (Polyketide Synthase 13).

A benzodiazepine inhibitor that directly interacts with RUNX1 and CBFβ, represses RUNX1/CBFβ-dependent transactivation in reporter assays.

A anti-HIV-1 compound that interferes with HIV-I integrase binding to viral DNA..

A angiotensin-converting enzyme (ACE) inhibitor for treatment of hypertension, heart failure, and after heart attacks..

A 4′-azidocytidine analogue that shows anti-HCV activity..

A 4′-azidocytidine analogue that shows anti-HCV activity..

A 385358 is a potent, selective, cell-permeable Bcl-XL inhibitor with Ki of 0.8 nM, displays >80-fold selectivity over Bcl-2 (Ki=64 nM).

A 2-cyanoaziridine derivative with antitumor activity in some types of cancer, including pancreatic, lung, breast, prostate, melanoma, and multiple myeloma.

A 10-fold more potent lysosomal autophagy inhibitor than hydroxychloroquine (HCQ)..

8-O-Acetyl shanzhiside methyl ester (ND01) is an iridoid glucoside isolated from the leaves of Lamiophlomis rotata Kudo, a Chinese folk medicinal plant in Xi-zang.

7DG (7-Desacetoxy-6,7-dehydrogedunin) is a selective inhibitor of protein kinase R (PKR) that directly interact with the C-terminal of PKR.

7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3.

7-BIA is a small molecule 7-butoxy illudalic acid analog that targets receptor-type protein tyrosine phosphatase D (PTPRD, IC50=1-3 uM) with some specificity.