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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC71587 | Nifuraldezone-15N3 |
Nifuraldezone-15N3 is the 15N3 labeled Nifuraldezone.
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| DC71586 | (R)-GNE-274 |
(R)-GNE-274 is a enantiomer of GNE-274. GNE-274 is a non-degrader that is structurally related to GDC-0927 (estrogen receptor degrader).
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| DC71585 | Tazide |
Tazide is an antineoplastic agent.
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| DC71584 | Opadotina |
Opadotina is a small molecule of anvatabart opadotin. Opadotina shows antineoplastic activity.
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| DC71583 | Fosimdesonide |
Fosimdesonide, a small molecule of adalimumab fosimdesonide, is a potent immunomodulator. Fosimdesonide shows anti-inflammatory activity.
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| DC71582 | Lafadofensine (D-(-)-Mandelic acid) |
Lafadofensine D-(-)-Mandelic acid is the monoamines reuptake inhibitor. Lafadofensine D-(-)-Mandelic acid has sufficient effects after short-term administration.
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| DC71581 | N-Butylfluorescein |
N-Butylfluorescein is an alkyl-substituted fluorescein, can be used for synthesis of fluorogenic substrates for assaying phosphatidylinositol-specific phospholipase C.
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| DC71580 | Cavutilide |
Cavutilide, benzamide, is used as an antiarrhythmic, antiarythmique.
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| DC71579 | N-Acryloyl-1-pyrenebutylamine |
N-Acryloyl-1-pyrenebutylamine is a potent fluorescent derivatization agent. N-Acryloyl-1-pyrenebutylamine combines with an alkyl-acrylamide side-chain to give fluorescence function on the polymer..
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| DC71578 | SG3400 delate(Mal-amido-PEG8) |
SG3400 delate (Mal-amido-PEG8) (compound 21) is an intermediate for the synthesis of ADC molecules. SG3400 delete is an effective toxin molecule with anticancer activity. SG3400 delete can be used in cancer research.
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| DC71576 | β-S-ARCA |
β-S-ARCA is a mRNA 7-methylguanosine (m7G) cap analog carrying a phosphorothioate (PS) moiety. mRNAs incorporating β-S-ARCA have elongated cellular half-lives and showed augmented protein expression. β-S-ARCA D1 has been applied in researching experimental mRNA-based anticancer vaccines.
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| DC71575 | 5,5'-Difluoro BAPTA |
5,5'-Difluoro BAPTA is the most widely used probe for studying cytosolic free Ca2+ by 19F NMR. 5,5'-Difluoro BAPTA has high selectivity for Ca2+. 5,5'-Difluoro BAPTA can inhibit the growth of pollen tube.
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| DC71574 | NHS-SS-Ac |
NHS-SS-Ac is an amine-reactive product synthesized from acetic acid.
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| DC71573 | Insulin lispro |
Insulin lispro is a recombinant human insulin analogue and is one of three rapid-acting insulin analogues available. Insulin lispro can be used for the research of hyperglycaemia in diabetes mellitus.
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| DC71572 | Bodipy 8-chloromethane |
BODIPY-8-chloromethane is a fluorophore. BODIPY-8-chloromethane can be used as as a fluorescent probe.
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| DC71571 | Fluorescein octadecyl ester |
Fluorescein octadecyl ester is a lipophilic fluorescent reagent is immobilized in a plasticized PVC membrane. Fluorescein octadecyl ester can reversibly recognize alcohol molecules and can be used to determine the concentration of ethanol in alcoholic drinks. Fluorescein octadecyl ester can be used as acceptor to make optrode membrane for the determination of picric acid.
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| DC71570 | Exo2 |
Exo2 is a secretion inhibitor. Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Exo2 blocks secretory cargo exit from the ER (endoplasmic reticulum) and disrupts the Golgi apparatus, but does not affect the morphology of the TGN (trans-Golgi network) Exo2 can stimulate calcium-dependent exocytosis in permeabilized adrenal chromaff in cells.
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| DC71569 | 2-Nitrophenanthraquinone |
2-Nitrophenanthraquinone is a bioactive compound.
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| DC71568 | Epitizide |
Epitizide, a benzothiadiazine, commonly found in combination Triamterene, is used to produce diuresis.
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| DC71567 | Ro 41-5253 |
Ro 41-5253 is an orally active selective retinoic acid receptor alpha (RARα) antagonist. Ro 41-5253 can bind RARα without inducing transcription or affecting RAR/RXR heterodimerization and DNA binding. Ro 41-5253 can inhibit cancer cell proliferation and induce apoptosis, has antitumor activity.
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| DC71566 | Dexamethasone oxetanone |
Dexamethasone oxetanone (Dex-Ox), a derivative of the glucocorticoid-selective steroid Dexamethasone (Dex), is an antiglucocorticoid. Dexamethasone oxetanone is an antiprogestin with significant agonist activity with progesterone receptor (PR) A and B isoforms.
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| DC71565 | GW1929 hydrochloride |
GW1929 hydrochloride is an orally active peroxisome proliferator-activated receptor-γ (PPARγ) agonist with a pKi of 8.84 for human PPAR-γ, and pEC50s of 8.56 and 8.27 for human PPAR-γ and murine PPAR-γ, respectively. GW1929 hydrochloride has antidiabetic efficacy and neuroprotective potential. GW1929 hydrochloride suppresses neuronal apoptosis and shows anti-inflammatory potential.
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| DC71564 | 2-(Tetradecylthio)acetic acid |
2-Tetradecylthio acetic acid is a pan-peroxisome proliferator activated receptor (pan-PPAR) activator. 2-Tetradecylthio acetic acid induces hypolipidemia. 2-Tetradecylthio acetic acid reduces plasma lipids and enhances hepatic fatty acid oxidation in rodents. 2-Tetradecylthio acetic acid increases the expression of genes involved in fatty acid uptake, activation, accumulation, and oxidation.
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| DC71563 | NXPZ-2 |
NXPZ-2 is an orally active Keap1-Nrf2 protein–protein interaction (PPI) inhibitor with a Ki value of 95 nM, EC50 value of 120 and 170 nM. NXPZ-2 can dose-dependently ameliorate Aβ[1-42]-Induced cognitive dysfunction, improve brain tissue pathological changes in Alzheimer’s disease (AD) mouse by increasing neuron quantity and function. NXPZ-2 can inhibit oxidative stress by increasing Nrf2 expression levels and promoting its cytoplasm to nuclear translocation, which is helpful for Keap1-Nrf2 PPI inhibitors and AD associated disease research.
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| DC71562 | EIF2α activator 1 |
EIF2α activator 1 (Compound 40) is an activator of eukaryotic initiation factor 2 alpha (eIF2α) phosphorylation. EIF2α activator 1 increases the expression level of eIF2α downstream proteins, ATF and CHOP. EIF2α activator 1 exhibits antiproliferative activity againist K562 and PBMC cells with IC50s of 4.00 and 19.3 μM, respectively.
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| DC71561 | EIF2α activator 2 |
EIF2α activator 2 (Compound 1) is an activator of eukaryotic initiation factor 2 alpha (eIF2α) phosphorylation. EIF2α activator 2 exhibits high potency in SRB cell proliferation assays (IC50=0.46 μM). EIF2α activator 2 exhibits antiproliferative activity againist K562 and PBMC cells with IC50s of 4.79 and 10.52 μM, respectively.
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| DC71560 | Enclomiphene |
Enclomiphene ((E)-Clomiphene) is a potent and orally active non-steroidal estrogen receptor antagonist, with antioestrogenic property. Enclomiphene can be used for the research of ovarian dysfunction, testosterone deficiency, male hypogonadism and type 2 diabetes.
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| DC71558 | Chymotrypsin |
Chymotrypsin (Chymotrypsin A) is a serine protease produced by the pancreas. Chymotrypsin cleaves protein chains at the carboxyl side of aromatic amino acids.
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| DC71557 | JO146 |
JO146 is a Chlamydia trachomatis high temperature requirement A (CtHtrA) protease inhibitor with IC50s of 21.86 and 1.15 μM for CtHtrA and human neutrophil elastase (HNE), respectively. JO146 can be used to inhibits bacterial infections.
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| DC71556 | Manusiran |
Manusiran is a potent TMPRSS6 (transmembrane protease serine 6) synthesis reducer.
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