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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DC79959 1,3-Dibutyrin
1,3-Dibutyrin is a glycerolipid.
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DC79958 1,3-Butyrin-2-stearin
1,3-Butyrin-2-stearin is an acylglycerol.
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DC79957 1,3-Butyrin-2-palmitin
1,3-Butyrin-2-palmitin is an acylglycerol.
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DC79956 1,3-Bis-aminooxy propane dihydrochloride
1,3-Bis-aminooxy propane dihydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC79955 1,2-Stearin-3-laurin
1,2-Stearin-3-laurin is an acylglycerol.
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DC79954 1,2-Stearin-3-elaidin
1,2-Stearin-3-elaidin is an acylglycerol.
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DC79953 1,2-Palmitolein-3-eicosatrienoin
1,2-Palmitolein-3-eicosatrienoin is an acylglycerol.
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DC79952 1,2-Olein-3-butyrin
1,2-Olein-3-butyrin is an acylglycerol.
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DC79951 1,2-Olein-3-acetyl
1,2-Olein-3-acetyl is an acylglycerol.
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DC79950 1,2-Linolenin-3-stearin
1,2-Linolenin-3-stearin is an acylglycerol.
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DC79949 1,2-Linolenin-3-olein
1,2-Linolenin-3-olein is an acylglycerol.
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DC79948 1,2-Linolenin-3-myristin
1,2-Linolenin-3-myristin is an acylglycerol.
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DC79947 1,2-Linolenin-3-laurin
1,2-Linolenin-3-laurin is an acylglycerol.
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DC79946 1,2-Linolein-3-caprylin
1,2-Linolein-3-caprylin is an acylglycerol.
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DC79945 1,2-Laurin-3-palmitin
1,2-Laurin-3-palmitin is an acylglycerol.
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DC79944 1,2-Eicosapentaenoin-3-docosahexaenoin
1,2-Eicosapentaenoin-3-docosahexaenoin is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
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DC79943 1,2-Butyrin-3-stearin
1,2-Butyrin-3-stearin is an acylglycerol.
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DC79942 1,2-Butyrin-3-linolein
1,2-Butyrin-3-linolein is an acylglycerol.
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DC79941 1,2-Arachidin-3-stearin
1,2-Arachidin-3-stearin is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
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DC79940 1,1-Dimethoxyhexadecane
1,1-Dimethoxyhexadecane is an ether lipid. Ether lipids are mainly found in cell membranes.
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DC79939 1,10-Bis(methylsulfinyl)decane
1,10-Bis(methylsulfinyl)decane (Compound IIf) is a decamethonium analogue and is a non-electrolytic sulfoxide compound. 1,10-Bis(methylsulfinyl)decane has low lethal (LD50 >37.5 mg/kg) effect in mice and neuromuscular blocking (ED50 >7 mg/kg) effects in cat.
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DC79938 1-(2-(But-3-yn-1-yloxy)ethoxy)-6-chlorohexane
1-(2-(But-3-yn-1-yloxy)ethoxy)-6-chlorohexane is a PROTAC linker that can be used in the synthesis of PROTACs.
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DC79937 (S,S,S)-AHPC-PEG2-NH2
(S,S,S)-AHPC-PEG2-NH2 is an isomer of Compound 15b. Compound 15b is a conjugate of a VHL ligand and linker. Compound 15b can be used to synthesize PROTAC. Compound 15b can be used in leukemia research.
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DC79936 (S,S)-SARM1-IN-9
(S,S)-SARM1-IN-9 (Compound MY-13A) is a stereoselective SARM1 inhibitor with covalent binding properties. (S,S)-SARM1-IN-9 covalently modifies Cys311 in the autoregulatory ARM domain of wild-type SARM1, thereby blocking NADase activity, without inhibiting the SARM1C311A or SARM1C311S mutants. (S,S)-SARM1-IN-9 blocks vacor- and vincristine-induced axon degeneration in primary rodent dorsal root ganglion neurons. (S,S)-SARM1-IN-9 can be used for research on axon degeneration-dependent neurological disorders, including chemotherapy-induced peripheral neuropathy.
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DC79935 (S,S) Bisoleoyl-lysobisphosphatidic acid
(S,S) Bisoleoyl-lysobisphosphatidic acid is a lysobisphosphatidic acid (LBPA). LBPA plays a role in modulating the cholesterol flux through endosomes.
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DC79934 (S,R,S,R)-AHPC-Me-CO-C7-N3
(S,R,S,R)-AHPC-Me-CO-C7-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S,R)-AHPC-Me based VHL ligand and a linker used in PROTAC technology. (S,R,S,R)-AHPC-Me-CO-C7-N3 can be connected to the ligand for protein by a linker to form PROTAC EZH2 Degrader-28.
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DC79933 (S,R,S)-BBO-11818
(S,R,S)-BBO-11818 (compound 59) is an inhibitor of KRAS that can be used in the research of cancer.
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DC79932 (S,R,S)-AHPC-Me-NHBoc
(S,R,S)-AHPC-Me-NHBoc is an E3 ubiquitin ligase VHL ligand used to recruit the VHL protein. (S,R,S)-AHPC-Me-NHBoc can be linked to a target protein ligand via a linker to form a PROTAC.
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DC79931 (S,R,S)-AHPC-Me-amide-C-O-PEG2-COOH
(S,R,S)-AHPC-Me-amide-C-O-PEG2-COOH is an E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-Me-amide-C-O-PEG2-COOH can be used for synthesis of PROTACs.
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DC79930 (S,R,S)-AHPC-CO-PEG3-NHBoc
(S,R,S)-AHPC-CO-PEG3-NHBoc is a synthesized E3 ligase ligand-linker conjugate that can be used to synthesize PROTAC G9a/GLP degrader 1. PROTAC G9a/GLP degrader 1 is a potent G9a/GLP PROTAC degrader with anti-cancer activity.
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