AU-16235 is an inactive epimer of AU-15330. AU-16235 has no effect on cancer cell survival and growth

Fasedienol is a neurochemical stimulator of the vomeronasal organ (VON). Fasedienol alleviates the symptoms of PMS and anxiety (extracted from patent WO1998014194A1).

Enfenamic acid is a nonsteroidal anti-inflammatory agent. Enfenamic acid suppresses wound healing.

DP-b99 is a chelator of zinc and calcium ions that acts selectively within cell membranes and has neuroprotective properties in animal models of stroke.

Atinvicitinib is a kind of pyrazole compound. Atinvicitinib has the potential for the research of atopic dermatitis (extracted from patent WO2021123094A1).

Feniralstat (compound 30), a pyrazole derivative, is a potent kallikrein inhibitor with an IC50 of 6.7 nM for Human plasma kallikrein (pKal). Feniralstat has no inhibition on Human KLKl, Human FXIa, Human Factor Xlla (all IC50>40 μM).

Itruvone is a intermediate of 17α-ethinylestradiol (EE2) during Fenton oxidation. Itruvone has an antidepressant effect.

S62798 is a selective and potent inhibitor of activated thrombin activatable fibrinolysis inhibitor (TAFIa) with an IC50 value of 6 mM.

Riodoxol is an antiviral agent. Riodoxol affects multiplication and maturation of the virus.

CP 316819 is a potent glycogen phosphorylase (GPase) inhibitor with antihyperglycemic effect (IC50 values are 17 and 34 nM against human skeletal muscle glycogen phosphorylase (huSMGPa) and liver glycogen phosphorylase (huLGPa) respectively).CP 316819 causes glycogen accumulation under normoglycemic conditions but permits glycogen utilization when glucose concentrations are low.CP-316819 prevents neuronal cell death and maintains brain electrical currents.

Lotrafiban is an orally-active platelet GPIIb/IIIa blocker for treatment of coronary and cerebrovascular disease.

Orbofiban is an orally active platelet GPIIb/IIIa antagonist that inhibits platelet aggregation.

Triperiden is an inhibitor of influenza virus multiplication. Triperiden targets the haemagglutinin of fowl plague virus (FPV) for antiviral activity and acts by inhibiting the conformational change in the haemagglutinin at acid pH. Triperiden is also anticholinergic anti-parkinsonism drug.

Lubeluzole is a neuroprotective anti-ischemic compound. Lubeluzole, but not its (-)-R-isomer, protects against sensorimotor deficits provoked by photochemical stroke in rats. Lubeluzole inhibited glutamate-stimulated guanosine 3',5'-cyclic monophosphate production with an IC50 of 37 nM. Lubeluzole also has the potential for developing a novel class of antibacterial adjuvants endowed with spasmolytic activity.

4-Sulfo-N-(4-aminobenzyl)-1,8-naphthalimide potassium is an inactive 1,8-Naphthalimide derivative. 4-Sulfo-N-(4-aminobenzyl)-1,8-naphthalimide potassium can be used as a negative control for the clathrin inhibitor 3-Sulfo-N-benzyl-1,8-naphthalimide, potassium salt.

Lexipafant is a platelet-activating factor (PAF) antagonist that inhibits the inflammatory response and is used in the treatment of acute pancreatitis.

2-nonyl-3-hydroxy-4-Quinolone (C9-PQS) is a quinolone compound produced by P. aeruginosa and other related bacterias. 2-nonyl-3-hydroxy-4-Quinolone is a quorum sensing (QS) signal molecule that controls the expression of many virulence genes as a function of cell population density.

Navamepent is an analog of naturally occurring resolvin E1 (a major dietary omega-3 polyunsaturated fatty-acid metabolite) with potent anti-inflammatory and cell survival benefits. Navamepent is highly effective against dry eye and goblet cell loss thereby accelerating tear production. Also, Navamepent can reduce corneal inflammation, epithelial damage, and accelerate corneal tissue repair. In addition, Navamepent can inhibit the release of several key proinflammatory mediators from corneal epithelial cells.

Linaprazan glurate inhibits exogenously or endogenously stimulated gastric acid secretion. Linaprazan glurate exhibits several advantageous properties, such as fast onset, high in vivo potency and/or long duration of action. Linaprazan glurate is useful in the research of gastrointestinal inflammatory diseases and peptic ulcer diseases (extracted from patent WO2010063876A1).

MK-5204 is an orally active β-1,3-glucan synthesis inhibitor.

Dipentamethylenethiuram Tetrasulfide is a material for constructing rubber (extracted from patent CN112876756A).

XTT (sodium) is used to assess cell viability as a function of redox potential. Actively respiring cells convert the water-soluble XTT to a water-soluble, orange colored formazan product.

HbF inducer-1 is an orally bioavailable fetal hemoglobin inducer.

OXS007417 induces differentiation of acute myeloid leukemia cells (EC50 = 48 nM) in vitro and shows antitumor effects in vivo.

Sucistil is an active compound. hemoglobin sucistil (bovine) is an oxygen carrier.

ART615 is the related isomer of ART558. ART615 elicits <10% Polθ inhibition at 12 µM, thus serving as a control for ART558 (IC50=7.9 nM).

Debotansine is a immunomodulator and antineoplastic.

O-GlcNAcase-IN-1 is a potent and novel OGA inhibitor with an IC50 value of 46 nM.

Retezorogant is a retinoid-related orphan receptor γ (RORγ) antagonist, extracted from patent WO2016093342 A1.

10-Nitrolinoleic acid is a potent peroxisome proliferator-activated receptor γ (PPARγ) agonist. 10-Nitrolinoleic acid competes with [3H]Rosiglitazone for binding to PPAR-γ, with an IC50 of 0.22 μM.