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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DC47831 Sanggenone H
Sanggenone H is found in Morus alba L.
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DC47825 Oleoside 11-methyl ester
Oleoside 11-methyl ester is a secoiridoid glucoside and possesses a strong cytotoxic activity against Hep-G2 cells.
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DC47820 Methyl p-hydroxyphenyllactate
Methyl p-hydroxyphenyllactate (MeHPLA) is an important cell growth-regulating agent which binds to nuclear type II binding sites in normal and malignant cells.
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DC47818 Pinosylvin monomethyl ether
Pinosylvin monomethyl ether has antibacterial effect and fungicidal activity.
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DC47816 Kulinone
Kulinone has cytotoxic effects against A549, H460 and HGC27 with IC50 values of 6.2 ± 0.1, 7.8 ± 1.2, 5.6 ± 0.2 μg/ml。
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DC47815 Samwirin A
Samwirin A is a promising radical scavenger in aqueous media at physiological pH.
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DC47814 Suomilide
Suomilide inhibits human trypsin-2 and -3, with IC50 values of 4.7 and 11.5 nM, respectively, while trypsin-1 is inhibited with an IC50 of 104 nM.
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DC47806 Rhodiocyanoside A
Rhodiocyanoside A is found to show antiallergic activity in a passive cutaneous anaphylaxis test in rat.
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DC47804 Rocaglaol
Rocaglaol induces apoptosis and cell cycle arrest in LNCaP cells.
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DC47802 Rotundatin
Rotundatin is useful in inhibition of the aggregation of platelets induced by arachidonic acid and collagen.
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DC47800 Monnieriside G
Monnieriside G is found in Cnidium monnieri fruits.
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DC47799 Methylsyringin
Methylsyringin exhibits anti-inflammatory activity in the LPS-stimulated RAW264.7 cells.
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DC47798 Rutaretin
Rutaretin is found in Atalantia racemosa.
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DC47795 Quebecol
Quebecol is a nutraceutical agent against periodontitis.
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DC47793 Peucedanocoumarin II
Peucedanocoumarin II can induce rice resistance to blast disease.
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DC47791 OJV-VI
OJV-VI is found in ophiopogonis.
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DC47789 Schisanwilsonin B
Schisanwilsonin B is a lignan from the fruits of Schisandra wilsoniana.
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DC47786 Moscatin
Moscatin inhibits AA-induced platelet aggregation in a concentration-dependent manner with IC50 values 37.2 μM .
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DC47784 Olivil monoacetate
Olivil monoacetate is found in Gymnosporia varialilis Loes.
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DC47783 Mulberrofuran Q
Mulberrofuran Q inhibits the formation of 12-hydroxy-5,8,10-heptadecatrienoic acid (HHT) and thromboxane B2 (cyclooxygenase products).
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DC47776 Millmerranone A
Millmerranone A shows the acetylcholinesterase inhibitory property.
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DC47769 Phenylpyropene C
Phenylpyropene C (S14-95), a JAK/STAT pathway inhibitor, can inhibit IFN-γ mediated expression of the reporter gene (IC50=5.4~10.8 μM). Phenylpyropene C also is an inhibitor of acyl-CoA, with an IC50 of 16.0 μM.
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DC47767 N6-Benzyl-5'-ethylcarboxamido adenosine
N6-Benzyl-5'-ethylcarboxamido adenosine is a selective A3 adenosine receptor agonist.
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DC47762 MeDTC
MeDTC (S-Methyl-N,N-diethylthiocarbamate Sulfone), a Disulfiram metabolite, is a potent, irreversible aldehyde dehydrogenase (ALDH) inhibitor.
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DC47759 Kazinol U
Kazinol U inhibits melanogenesis through the inhibition of tyrosinase-related proteins via AMPK activation.
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DC47756 Plantainoside D
Plantainoside D shows ACE inhibitory activity with IC50 2.17 mM. And plantainoside D is a promising IKK-β inhibitor.
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DC47751 Lepidozin G
Lepidozin G inhibits the growth of a panel of cancer cell lines with IC50 values ranging from 4.2 ± 0.2 to 5.7 ± 0.5 μM. Lepidozin G induces PC-3 cell death via mitochondrial-related apoptosis.
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DC47750 L-threo-PPMP
L-threo-PPMP is a GlcT (UDP-Glc: Ceramide β1,1glucosyltransferase) inhibitor. L-threo-PPMP inhibits glycosphingolipid biosynthesis and induces apoptosis. L-threo-PPMP has anti-cancer activity.
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DC47747 MDP1 acetate
MDP1 acetate, a Melittin-derived peptide, alters the integrity of both Gram-positive and Gram-negative bacterial membranes and kills the bacteria via membrane damages. MDP1 acetate has a high-antibacterial activity against multidrug resistant (MDR) and reference strains of S. aureus, E. coli, and P. aeruginosa.
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DC47746 MDP1
MDP1, a Melittin-derived peptide, alters the integrity of both Gram-positive and Gram-negative bacterial membranes and kills the bacteria via membrane damages. MDP1 has a high-antibacterial activity against multidrug resistant (MDR) and reference strains of S. aureus, E. coli, and P. aeruginosa.
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