Antifungal agent 17 exhibits excellent antifungal properties against B. cinerea with an EC50 value of 2.86 μg/mL.

Antifungal agent 19 shows the potent antifungal activity (EC50 = 0.72 μM).

Antifungal agent 13 exhibits remarkable antifungal activity against Sclerotinia sclerotiorum with an EC50 value of 1.25 mg/L.

Antifungal agent 14 exhibits broad-spectrum activity against the fungal strains with excellent minimum inhibitory concentration values.

Antifungal agent 15 has the most potent activity with EC50 values of 0.52 and 0.50 μg/mL against S. sclerotiorum and B. cinerea, respectively.

Antifungal agent 18 is a novel antifungal agent for the treatment of fungal infection.

5-epi-Jinkoheremol exhibits more potent fungicidal activity than validamycin.

Antifungal agent 20 exhibits remarkable antifungal activity against Colletotrichum gloeosprioides, Rhizoctonia solani, Phytophthora nicotianae var. nicotianae, Diplodia pinea, Colletotrichum acutatum, and Fusarium oxysporum f. sp. niveum.

3-Aminopropylphosphinic acid (3-APPA), a phosphonic analog of GABA, is a GABAB receptor agonist.

5-HT7R antagonist 1 is a G protein-biased antagonist against 5-HT7R (Ki = 6.5 nM).

5-HT7R antagonist 1 (free base) is a G protein-biased antagonist against 5-HT7R (Ki = 6.5 nM).

(R)-Pomalidomide-pyrrolidine, a CRBN ligand, can be connected to the ligand for protein by a linker to form PROTACs.

(Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine) hydrochloride, an active metabolite of Tolterodine, is a mAChR antagonist (Ki values of 2.3 nM, 2 nM, 2.5 nM, 2.8 nM, and 2.9 nM for M1, M2, M3, M4, and M5 receptors, respectively). (Rac)-5-Hydroxymethyl Tolterodine hydrochloride can be used for overactive bladder research.

(Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine), an active metabolite of Tolterodine, is a mAChR antagonist (Ki values of 2.3 nM, 2 nM, 2.5 nM, 2.8 nM, and 2.9 nM for M1, M2, M3, M4, and M5 receptors, respectively). (Rac)-5-Hydroxymethyl Tolterodine can be used for overactive bladder research.

ADAM8-IN-1 is a potent ADAM8 inhibitor with an IC50 value of 73 nM.

(S)-Salsolidine is a weak monoamine oxidase (MAO) inhibitor (Ki=63 μM). The R enantiomer of Salsolidine is more potent than the S form (Ki=26 μM).

(+)-Cinchonaminone shows monoamine oxidase (MAO) inhibitory activity.

(32-Carbonyl)-RMC-5552 is a potent mTOR inhibitor. (32-Carbonyl)-RMC-5552 inhibits mTORC1 and mTORC2 substrate (p-P70S6K-(T389), p-4E-BP1-(T37/36), AND p-AKT1/2/3-(S473)) phosphorylation with pIC50s of > 9, >9 and between 8 and 9, respectively (patent WO2019212990A1, example 2).

Anabaseine, an alkaloid, stimulates a wide variety of animal nicotinic acetylcholine receptors (AChRs), especially the neuromuscular receptors and α7 AChRs.

ABT-384 is a selective 11-β-hydroxysteroid dehydrogenase type 1 (HSD-1) inhibitor. ABT-384 blocks regeneration of active cortisol. ABT-384 exhibits high affinity against rodent, monkey, and human HSD-1 whit a Ki of 0.1-2.7 nM.

4′-Bromoflavone, a cancer chemopreventive agent, is a potent phase II detoxification enzymes inducer.

Anticancer agent 14 is a lead compound (IC50: 0.20 to 0.65 μM) that induces apoptosis, cell cycle arrest, and loss of mitochondrial membrane potential in breast cancer cells.

Anticancer agent 16 exhibits good cytotoxic activity against HCT-116, NCI-H460, and SKOV3 cell lines with IC50 8.55 μΜ, 5.41 μΜ, and 6.4 μΜ, respectively.

Anticancer agent 12 is unexpectedly devoids of hepatotoxicity while maintaining cytotoxic activity in malignant cells.

Antidepressant agent 2 exerts pronounced antidepressant activity (MED 0.1 mg/kg).

Anti-inflammatory agent 6 blocks the phosphorylation of I kappa b kinase α/β (IKKα/β), IκBα, and nuclear factor kB p65 (NF-κB p65) which is a key controller of inflammation, thereby showing anti-inflammatory potential.

Anticancer agent 17 displays potent anticancer activities against HeLa and A2780 cells with IC50 values of 0.19 μM and 0.09 μM, respectively.

(6R,7S)-Cefminox sodium heptahydrate is an isomer of Cefminox sodium heptahydrate. Cefminox sodium heptahydrate is a β-lactam cephalosporin antibiotic, which exhibits a broad spectrum of antibacterial activity.

Anticancer agent 13 is an anticancer agent from dicarboxylic acids and amines.

ANAT inhibitor-1 is a human aspartate N-acetyltransferase (ANAT) inhibitor for canavan disease.