Huanglongmycin N is a DNA topoisomerase I inhibitor (EC50 = 14 μM).

Dovitinib RIBOTAC is a targeted RNA degrader that cleaves pre-miR-21 with enhanced potency and selectivity.

Anti-inflammatory agent 5 displays potent inhibition of NO generation in lipopolysaccharide-induced BV-2 microglial cells.

(3ξ,4ξ,5ξ,6ξ,7ξ,11ξ)-3,6-Dihydroxy-8-oxo-9-eremophilene-12-oic acid is a new phytotoxin of Alternaria alternata ssp. tenuissima isolates associated with fruit spots on apple.

(9S)-Macrocidin B shows a weaker herbicidal effect than macrocidin A.

Amakusamine inhibits the receptor activator of nuclear factor-κB ligand (RANKL)-induced formation of multinuclear osteoclasts with an IC50 value of 10.5 μM in RAW264 cells.

14-Benzoylneoline is found in Aconitum subcuneatum.

3,5-O-Dicaffeoylquinic acid reverses Trimethyltin-induced learning and memory deficits.

3β-Methoxy-2,3-dihydrowithaferin A is one of withanolides found in Withania somnifera.

2-Hydroxyanthraquinone, a natural compound, possesses antitumor and immunosuppressive activity.

(±)-Phrymarolin II is a promising new class of plant virus (tobacco mosaic virus) inhibitors.

2,3-Didehydrosomnifericin is one of withanolides found in Withania somnifera.

7,22,25-Stigmastatrienol is one of sterols of Berrettina pumpkin seed oil.

2,3-Bis(3-indolylmethyl)indole significantly suppresses RANKL-induced osteoclast formation, actin ring formation, and bone resorption in a concentration-dependent manner.

3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone displays cytotoxicity of 1.32, 3.92 and 5.22 μm against the human cervical carcinoma HeLa, human breast carcinoma MCF-7, and human hepatocarcinoma Hep3B cells.

25(S)-Ruscogenin-1-O-α-L-rhamnopyranosyl (1→2)-β-D-xylopyranoside shows inhibitory activity of neutrophil respiratory burst stimulated by PMA(phorbol myristate acetate).

27-O-Acetyl-withaferin A is found in Withania aristata.

7Z-Trifostigmanoside I is found in Polygala hongkongensis Hemsl.

Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2 is serum stable, non-toxic to neuronal cells, and selectivity inhibits the fibrilization of tau over Aβ42.

8-Methylsulfinyloctyl isothiocyanate, an isothiocyanate, has antimicrobial activity and remarkable inhibitory activity against plant growth. 8-Methylsulfinyloctyl isothiocyanate impair COX-2 mediated inflammatory responses in LPS stimulated raw macrophages.

Adenosine receptor antagonist 1 is a A2aR-selective antagonist with an IC50 of 0.29 nM and displays 14-fold more selective for A2aRthan A2bR.

ALK-IN-12 is a potent and orally active ALK inhibitor with an IC50 of 0.18 nM. ALK-IN-12 also inhibits IGF1R and InsR (IC50=20.3 and 90.6 nM). Antitumor activities.

ALK-IN-13 is an ALK inhibitor, extracted from patent US20130225528A1, example 19.

A4B17 is an androgen receptor N-terminal inhibitor for treating androgen-responsive prostate cancer.

142I5 is a potent ML-IAP Lys-covalent inhibitor with an IC50 value of 11 nM.

(±)-Norcantharidin ((±)-NCTD) is a compound possessing anti-angiogenetic activity with potential use in anti-cancertherapy. (±)-Norcantharidin could prevent tumorigenesis by inhibiting cell proliferation, inducing apoptosis and the cell cycle arrest, and anti-angiogenic effects.

Antibacterial agent 62 is a novel redox cycling antituberculosis chemotype with potent bactericidal activity against growing and nutrient-starved phenotypically drug-resistant nongrowing bacteria.

Anti gram-positive/negative bacteria agent 1 is an antibiotic conjugate with an artificial MECAM-based siderophore.

Antibacterial agent 63, a conjugate of aztreonam to a siderophore mimetic, shows activity against gram-negative bacteria.

(8'α,9'β-Dihydroxy)-3-farnesylindole shows strong inhibitory activity (EC50 9.8 μM) against B. subtilis.