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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DC40909 Cyanazine
Cyanazine is an herbicide which can inhibits photosynthesis of plants. Cyanazine is a selective systemic herbicide for crops such as corn, peas, and broad beans, which is used to control a variety of grass weeds and broadleaf weed.
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DC40908 Haloxyfop-P-methyl
Haloxyfop-P-methyl is an aryloxyphenoxypropionate herbicide. Haloxyfop-P-methyl can be absorbed by roots or foliage and hampers lipogenesis and increases oxidative stress in target plants.
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DC40907 Metazachlor
Metazachlor is a herbicide of the chloroacetamide class. Metazachlor is an inhibitor of the synthesis of long chain fatty acids and has an effect on cell division or tissue differentiation in the germinating and emerging weed target species.
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DC40906 Diquat dibromide hydrate
Diquat dibromide hydrate is a diazine-like herbicide including two nitrogen atoms.
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DC40905 Fluroxypyr-meptyl
Fluroxypyr-meptyl (Fluroxypyr-1-methylheptyl ester), a synthetical phytohormone, is used as herbicide agent.
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DC40904 Bromoxynil octanoate
Bromoxynil octanoate is an herbicide widely applied to maize, is potentially toxic to both animals and humans.
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DC40903 Ethofumesate
Ethofumesate, a chiral herbicide, acts by inhibiting mitosis and reducing photosynthesis and plant respiration.
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DC40902 Diclofop-methyl
Diclofop-methyl, a common post-emergence herbicide, is widely used in agriculture production. Diclofop-methyl increases the proton permeability of isolated oat-root tonoplast.
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DC40901 ARRY-382
ARRY-382 is a potent, oral and highly selective inhibitor of CSF1R/c-Fms with an IC50 of 9 nM. ARRY-382 can be used for the research of advanced or metastatic cancers.
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DC40900 MI-3454
MI-3454 is an orally active, highly potent and selective menin-MLL1 interaction inhibitor with an IC50 of 0.51 nM. MI-3454 inhibits proliferation, induces differentiation and complete remission or regression of leukemia in mouse models of MLL1-rearranged or NPM1-mutated leukemia through downregulation of key genes involved in leukemogenesis.
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DC40899 Tribenuron
Tribenuron, a slow acting sulfonylurea herbicide, controls broadleaf weed.
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DC40898 Triclopyricarb
Triclopyricarb (SYP-7017) is a strobilurin fungicide that can be used in crops disease control. Triclopyricarb inhibits mycelial growth with EC50 values ranged from 0.006 μg/mL to 0.047 μg/mL.
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DC40897 Adenosine 5'-succinate
Adenosine 5'-succinate is a chemically AMP-related compound and potently inhibits Denatonium benzoate/taste receptor activation of transducin.
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DC40896 THZ-P1-2
THZ-P1-2 is a first-in-class and selective PI5P4K inhibitor, with an IC50 of 190 nM for PI5P4Kα. THZ-P1-2 covalently targets cysteines on a disordered loop in PI5P4Kα/β/γ. THZ-P1-2 causes autophagy disruption and upregulates TFEB signaling. THZ-P1-2 displays anticancer activity in leukemia cell lines.
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DC40895 BRD9500
BRD9500 is an orally active phosphodiesterases 3 (PDE3) inhibitor with IC50s of 10 and 27 nM for PDE3A and PDE3B, respectively. Antitumor activity.
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DC40894 3α-Hydroxy pravastatin sodium
3α-Hydroxy pravastatin sodium is the major metabolite of Pravastatin. Pravastatin is a competitive HMG-CoA reductase inhibitor.
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DC40893 2-Hydroxy atorvastatin lactone
2-Hydroxy atorvastatin lactone is a metabolite of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids.
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DC40892 (Rac)-3′-Hydroxy simvastatin
(Rac)-3′-Hydroxy simvastatin is a metabolite of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM.
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DC40891 Simvastatin Acyl-β-D-glucuronide
Simvastatin Acyl-β-D-glucuronide is a metabolite of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM.
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DC40889 Cimetidine sulfoxide
Cimetidine sulfoxide (Cimetidine sulphoxide) is a sulfoxide metabolite of Cimetidine. Cimetidine is a histamine H2-receptor antagonist. Cimetidine has the potential for peptic ulcer disease and upper gastrointestinal haemorrhage treatment.
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DC40887 Thiol-PEG-Tetrazine (MW 5kDa)
Thiol-PEG-Tetrazine (MW 5kDa) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC40886 Oxazosulfyl
Oxazosulfyl is a potent agricultural fungicide. Oxazosulfyl can be used as an insecticide against major rice pests.
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DC40885 β-D-glucuronide-pNP-carbonate
β-D-glucuronide-pNP-carbonate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC40883 β-D-tetraacetylgalactopyranoside-PEG1-N3
β-D-tetraacetylgalactopyranoside-PEG1-N3 is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC40881 Ald-PEG23-SPDP
Ald-PEG23-SPDP is a cleavable 23 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC40880 GS-704277
GS-704277 is an alanine metabolite of Remdesivir. Remdesivir, a nucleoside analogue with effective antiviral activity, is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro.
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DC40879 Sepimostat
Sepimostat exhibits neuroprotective activity via NR2B N-methyl-D-aspartate receptor antagonism at the Ifenprodil-binding site of the NR2B subunit. Sepimostat inhibits the Ifenprodil binding with a Ki value of 27.7?μM.
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DC40878 Cryptophycin 1
Cryptophycin 1 is a potent cytotoxic antimicrotubule agent which is isolated from Nostoc sp. Cryptophycin 1 can induce cells apoptosis, and exhibits antitumor activity and exceptional antiproliferative potency.
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DC40877 Mechercharmycin A
Mechercharmycin A is a cytotoxic substance isolated from marine-derived Thermoactinomyces sp. YM3-251. Mechercharmycin A exhibits relatively strong antitumor activity.
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DC40874 CPI-1612
CPI-1612 is a highly potent, orally active EP300/CBP histone acetyltransferase (HAT) inhibitor with an IC50 of 8.1 nM for EP300 HAT. CPI-1612 has an anticancer activity.
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