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Cat. No. Product Name Field of Application Chemical Structure
DC36571 De(5-carboxamide)oxcarbazepine
De(5-carboxamide)oxcarbazepine is a compound useful in organic synthesis.
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DC36528 Pentanochlor
Pentanochlor can be used in agricultural use and biological study of herbicide composition containing a pyrazolyl pyrazole derivative. The impairment of mobility and development in freshwater snails (Physa fontinalis and Lymnaea stagnalis) caused by herbicides.
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DC36506 Sodium methanearsonate
Sodium methanearsonate is also known as Monosodium Acid Methane Arsonate Sesquihydrate. It is an environmental toxic compound. It also functions as a commonly used herbicide for weed control in grass.
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DC36479 2,2'-Dipyridyl disulfide
2,2'-Dipyridyl disulfide, also known as OPSS, is a useful reagent for determination of sulfhydryl groups, preparation of amino acid active esters and the thio esters of phosphoric acid. It acts as a peptide coupling reagent and as an oxidizing agent. It is also used for the activation of glycosides.
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DC36474 BODIPY 505/515
BODIPY 505/515 is a lipophilic fluorescent probe that localizes to intracellular lipid bodies and has been used to label lipid droplets. BODIPY 505/515 has been used for electron, epifluorescent, and confocal microscopy, as well as flow cytometry applications in various algae species. It displays excitation/emission maxima of 505/515 nm, respectively, and has been used for live and fixed cell applications.
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DC36461 Hydroxystilbamidine
Hydroxystilbamidine is a fluorescent neuronal retrograde tracer that labels the neuronal cell body as well as proximal dendrites. It is also a nucleic acid dye that can be used to label DNA and RNA in fixed or unfixed dead cells. It displays an excitation maximum of 360 nm and emission maxima of 450 and 600 nm when bound to DNA but only emits at 450 nm when bound to RNA.
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DC36453 Tetrahydropiperine
Tetrahydropiperine is a piperine derivative that has diverse biological activities. It is an agonist of transient receptor potential vanilloid type 1 (TRPV1). It inhibits the cytochrome P450 (CYP) isoform CYP1A1/arylhydrocarbon hydroxylase (AHH) and 7-methoxycoumarin O-demethylase (MOCD) activity in rat liver microsomes.
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DC36439 Bostrycin
Bostrycin is an anthraquinone with antibacterial, antiproliferative, and phytotoxic properties. It is active against Gram-positive bacteria, including methicillin-resistant S. aureus (MRSA), M. tuberculosis, and C. botulinum. Bostrycin inhibits proliferation of A549 lung adenocarcinoma cells as well as halts the cell cycle at the G0/G1 phase and induces apoptosis in A549 cells. Bostrycin has been used as a cross-linking agent for protein immobilization that retains bacteriostatic activity when immobilized on nonwoven polypropylene fabric.
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DC36426 BB-Cl-Yne
BB-Cl-Yne is a cell-permeable derivative of the protein arginine deiminase (PAD) inhibitor BB-Cl-amidine that contains an alkyne moiety for use in click chemistry reactions. BB-Cl-Yne inhibits PAD1-4 and has been used for labeling PADs in cell-free and cell-based assays, followed by click reactions with azide-modified TAMRA or biotin reporters.
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DC36407 BB-F-Yne
BB-F-Yne is a cell-permeable derivative of the protein arginine diminase (PAD) inhibitor BB-Cl-amidine that contains an alkyne moiety for use in click chemistry reactions. BB-F-Yne inhibits PAD1-4 and has been used for labeling PADs in cell-free and cell-based assays, followed by click reactions with azide-modified TAMRA or biotin reporters.
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DC36396 Brevicompanine B
Brevicompanine B is a fungal metabolite that has plant growth and circadian rhythm regulatory activity. Brevicompanine B inhibits primary root growth in Arabidopsis seedlings and disrupts the transcription of various genes involved in the regulation of plant circadian rhythm. It is active against P. falciparum.
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DC36377 Integracin B
Integracin B is a fungal metabolite and an inhibitor of HIV-1 integrase.
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DC36369 Zelkovamycin
Zelkovamycin is a cyclic peptide antibiotic that inhibits growth of X. oryzae, P. oryzae, S. aureus, and A. laidlawii in a concentration-dependent manner.
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DC36333 Photoswitchable PAD inhibitor
Photoswitchable PAD inhibitor is a photoactivated protein arginine deiminase (PAD) inhibitor and a derivative of BB-Cl-amidine that contains an azobenzene photoswitch allowing optical control of PAD activity. Without photoactivation, it is a weak inhibitor of PAD2 and is less potent than BB-Cl-amidine in inhibiting citrulline production in vitro. It does not inhibit histone H3 citrullination in HEK293T cells overexpressing PAD2. However, it can rapidly be photoactivated with UV-A radiation to the more active cis-isomer, which is an irreversible, competitive inhibitor of histone H3 citrullination.
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DC36311 cis VH 032
cis VH 032, amine dihydrochloride is a negative control for the functionalized VHL ligand VH 032, amine.
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DC36310 VH032 phenol - linker 2
VH032 phenol - linker 2 is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development. It incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand.
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DC36280 Prostaglandin D synthase (hematopoietic-type) inhibitor F092
Prostaglandin D synthase (hematopoietic-type) inhibitor F092 is an inhibitor of hematopoietic-type prostaglandin D synthase (H-PGDS).
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DC36276 LH1306
LH1306 is an inhibitor of the interaction between programmed cell death 1 (PD-1) and its ligand PD-L1. It increases the activation of Jurkat cells expressing PD-1 in co-culture with U2OS or CHO cells expressing PD-L1.
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DC36271 MD001
MD001 is a dual agonist of peroxisome proliferator-activated receptor α (PPARα) and PPARγ. It binds to PPARα and PPARγ but does not bind to PPARβ/δ. It increases transcriptional activity of PPARα and PPARγ and glucose consumption. MD001 decreases levels of glucose, insulin, free fatty acids, triglycerides, LDL, alanine aminotransferase (ALT), and aspartate aminotransferase (AST) in blood and reduces the size and number of hepatic lipid droplets in diabetic db/db mice.
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DC36262 Pyrenophorol
Pyrenophorol is a fungal metabolite that has been found in Alternaria and has diverse biological activities. It inhibits human topoisomerase II α when used at concentrations of 75 and 100 μM. It is active against S. cerevisiae (MIC = 4 μM) and M. violaceum. Pyrenophorol induces leaf necrosis and chlorophyll retention in wild oats when used at a concentration of 64 μM.
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DC36250 NSC 34803
Thymohydroquinonee is a quinone that has been found in N. sativa seeds and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radicals and inhibits growth of A2780, OVCAR-8, CIS-A2780 ovarian cancer cells, and immortalized human ovarian epithelial cells. It is also active against P. falciparum in vitro.
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DC36243 CAY10735
CAY10735 is an anticancer compound that inhibits proliferation of melanoma, breast, pancreatic, and lung cancer cell lines by inhibiting the epithelial-to-mesenchymal transition (EMT).
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DC36191 AM-3102
AM-3102 is an OEA analog that stimulates PPARα transcriptional activity and prolongs feeding latency. It is resistant to enzymatic hydrolysis and is as potent as OEA in enhancing transcriptional activity of PPARα and reducing food intake in free-feeding rats. AM3102 demonstrates weak affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors.
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DC36182 Altimol
Nitrefazole is a nitroimidazole derivative with the ability to inhibit aldehyde dehydrogenase. This enzyme crucial to the metabolism of alcohol and is suitable for aldehyde dehydrogenase (ALDH) related research.
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DC36164 AI3-52581
Canavanine sulfate is a biochemical with antimutagenic activity. This product has been shown to potentiate the cytotoxicity of doxorubicin and cisplatin in arginine deprived human cancer cells
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DC36159 AI3-51270
Methylguanidine hydrochloride is a biochemical that can be used in the synthesis of biaryl derivatives which were evaluated as BACE1 inhibitors.
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DC36158 3177 R.P.
Melarsen oxide is a glutathione reductase inhibitor.
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DC36057 Pyrantel pamoate
Pyrantel pamoate is a broad spectrum antinematodal anthelmintic.
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DC36054 N-Antipyrinylnicotinamide
Nifenazone is a drug used as an analgesic for a number of rheumatic conditions.
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DC36029 (2-pyridyldithio)-PEG2-t-butyl ester
(2-pyridyldithio)-PEG2-t-butyl ester is a thiol PEG Linker.
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