Cat. No. | Product Name | Field of Application | Chemical Structure |
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DC22165 | MRS4478 |
MRS4478 is a potent, highly specific amtagonist of P2Y14 receptor with IC50 of 269 nM, does not display extensive off-target interactions with biogenic amine receptors..
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DC22164 | MRS4458 |
MRS4458 is a potent, highly specific amtagonist of P2Y14 receptor with IC50 of 169 nM, does not display extensive off-target interactions with biogenic amine receptors..
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DC12260 | MRS1177 |
MRS1177 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 0.3 nM.
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DC23740 | MRS 2485 |
MRS 2485 is a potent, irreversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity..
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DC23733 | MRS 2481 |
MRS 2481 is a potent, reversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity.
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DC23471 | MRS 2179 tetrasodium |
MRS 2179 is a potent, selective, competitive P2Y1 receptor antagonist with Kb of 100 nM.
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DC23483 | MRS 2179 |
MRS 2179 is a potent, selective, competitive P2Y1 receptor antagonist with Kb of 100 nM.
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DC23711 | MRL20 |
MRL20 is a novel synthetic PPARγ ligand and orthosteric agonist with canonical LBP binding affinity of 2 nM.
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DC21343 | MRL-1237 |
MRL-1237 is a potent and selective inhibitor of the replication of Enteroviruses with EC50 of 1-10 uM, targets the nonstructural 2C protein.
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DC21923 | MRK-A |
MRK-A is a potent, highly selective, brain penetrant inhibitor of mutant IDH1 with IC50 of 5 nM, displays a 10,000-fold mutant to wildtype selectivity ratio.
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DC23616 | MRK-696 |
MRK-696 is a non-selective benzodiazepine receptor partial agonist..
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DC23655 | MRK-623 |
MRK-623 is a potent, α2/α3 subunit functionally selectiviie GABAA receptor agonist..
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DC23877 | MRK-560 |
MRK-560 is a potent, brain-penetrant and orally bioavailable γ-secretase inhibitor that inhibits proteolytic cleavage of APP over the Notch pathway.
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DC20465 | mPGES1-IN-17d |
mPGES1-IN-17d is a potent, selective mPGES-1 inhibitor with enzyme IC50 of 8 nM, A549 cell IC50 of 16.24 nM, human whole blood IC50 of 249.9 nM.
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DC20464 | mPGES1-IN-16 |
mPGES1-IN-16 is a potent and selective mPGES-1 inhibitor with IC50 of 1 nM.
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DC22554 | MP-A08 |
MP-A08 is a first-in-class, highly selective, ATP competitive sphingosine kinase (SphK) inhibitor (Ki of 6.9/27 uM for SK2/SK1).
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DCAPI1572 | Moxonidine hydrochloride |
Moxonidine hydrochloride
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DCAPI1331 | Moxonidine |
Moxonidine
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DC12485 | Mosedipimod |
Mosedipimod (EC-18, 1-palmitoyl-2-linoleoyl-3-acetylglycerol) is a synthetic monoacetyldiaglyceride that stimulates T cell production of IL-2, IL-4, IL-12, IFN-γ, and GM-CSF in vitro.
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DC8931 | Mosapride |
Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist.
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DC20042 | Monooctyl succinate |
Monooctyl succinate is a monoester, which can be used as a surfactants and a potential fragrance releaser.
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DCAPI1006 | Monobenzone (Benoquin) |
Monobenzone (Benoquin)
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DCAPI1363 | Mometasone furoate |
Mometasone furoate
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DC8991 | Molsidomine |
Molsidomine is an orally active, long acting vasodilating drug, metabolized in the liver to the active metabolite linsidomine, which is an unstable compound that releases nitric oxide (NO) upon decay as the actual vasodilating compound.
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DC9425 | Molindone (hydrochloride) |
Molindone is a therapeutic antipsychotic, used in the treatment of schizophrenia, works by blocking the effects of dopamine in the brain, leading to diminished psychoses.
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DC20462 | MNK-IN-54 |
MNK-IN-54 is a potent, orally bioavailable dual MNK1/2 and BCR-ABL1 inhibitor with IC50 of 20/10/200/10 nM for Abl T315I/ wt Abl/MNK1/MNK2, respectively.
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DC21336 | MNKI-8e |
MNKI-8e (MNK inhibitor 8e) is a potent, selective MNK inhibitor that inhibits Mnk2 with Ki of 0.37 uM, displays >34-fold and 4-fold over CDK2 (Ki>10 uM) and CDK9 (Ki=1.66 uM).
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DC21338 | MNKI-85 |
MNKI-85 is a potent and selective Mnk2 inhibitor with Ki of 31 nM, displays no inhibitory activities against Mnk1, CDK2A, CDK9T, and CDK4D.
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DC21337 | MNKI-19 |
MNKI-19 is a potent and dual-specific Mnk inhibitor with Ki of 186 nM and 68 nM for Mnk1 and Mnk2, respectively.
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DC20463 | MNK inhibitor 9 |
MNK inhibitor 9 is a potent, selective MAPK-interacting kinase (MNK1 and MNK2) inhibitor with IC50 of 3 nM for both, with no activity aginst CDK1/2 (IC50>25 uM).
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