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Other Targets

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Cat. No. Product Name Field of Application Chemical Structure
DC22165 MRS4478
MRS4478 is a potent, highly specific amtagonist of P2Y14 receptor with IC50 of 269 nM, does not display extensive off-target interactions with biogenic amine receptors..
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DC22164 MRS4458
MRS4458 is a potent, highly specific amtagonist of P2Y14 receptor with IC50 of 169 nM, does not display extensive off-target interactions with biogenic amine receptors..
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DC12260 MRS1177
MRS1177 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 0.3 nM.
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DC23740 MRS 2485
MRS 2485 is a potent, irreversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity..
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DC23733 MRS 2481
MRS 2481 is a potent, reversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity.
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DC23471 MRS 2179 tetrasodium
MRS 2179 is a potent, selective, competitive P2Y1 receptor antagonist with Kb of 100 nM.
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DC23483 MRS 2179
MRS 2179 is a potent, selective, competitive P2Y1 receptor antagonist with Kb of 100 nM.
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DC23711 MRL20
MRL20 is a novel synthetic PPARγ ligand and orthosteric agonist with canonical LBP binding affinity of 2 nM.
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DC21343 MRL-1237
MRL-1237 is a potent and selective inhibitor of the replication of Enteroviruses with EC50 of 1-10 uM, targets the nonstructural 2C protein.
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DC21923 MRK-A
MRK-A is a potent, highly selective, brain penetrant inhibitor of mutant IDH1 with IC50 of 5 nM, displays a 10,000-fold mutant to wildtype selectivity ratio.
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DC23616 MRK-696
MRK-696 is a non-selective benzodiazepine receptor partial agonist..
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DC23655 MRK-623
MRK-623 is a potent, α2/α3 subunit functionally selectiviie GABAA receptor agonist..
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DC23877 MRK-560
MRK-560 is a potent, brain-penetrant and orally bioavailable γ-secretase inhibitor that inhibits proteolytic cleavage of APP over the Notch pathway.
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DC20465 mPGES1-IN-17d
mPGES1-IN-17d is a potent, selective mPGES-1 inhibitor with enzyme IC50 of 8 nM, A549 cell IC50 of 16.24 nM, human whole blood IC50 of 249.9 nM.
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DC20464 mPGES1-IN-16
mPGES1-IN-16 is a potent and selective mPGES-1 inhibitor with IC50 of 1 nM.
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DC22554 MP-A08
MP-A08 is a first-in-class, highly selective, ATP competitive sphingosine kinase (SphK) inhibitor (Ki of 6.9/27 uM for SK2/SK1).
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DCAPI1572 Moxonidine hydrochloride
Moxonidine hydrochloride
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DCAPI1331 Moxonidine
Moxonidine
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DC12485 Mosedipimod
Mosedipimod (EC-18, 1-palmitoyl-2-linoleoyl-3-acetylglycerol) is a synthetic monoacetyldiaglyceride that stimulates T cell production of IL-2, IL-4, IL-12, IFN-γ, and GM-CSF in vitro.
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DC8931 Mosapride
Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist.
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DC20042 Monooctyl succinate
Monooctyl succinate is a monoester, which can be used as a surfactants and a potential fragrance releaser.
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DCAPI1006 Monobenzone (Benoquin)
Monobenzone (Benoquin)
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DCAPI1363 Mometasone furoate
Mometasone furoate
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DC8991 Molsidomine
Molsidomine is an orally active, long acting vasodilating drug, metabolized in the liver to the active metabolite linsidomine, which is an unstable compound that releases nitric oxide (NO) upon decay as the actual vasodilating compound.
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DC9425 Molindone (hydrochloride)
Molindone is a therapeutic antipsychotic, used in the treatment of schizophrenia, works by blocking the effects of dopamine in the brain, leading to diminished psychoses.
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DC20462 MNK-IN-54
MNK-IN-54 is a potent, orally bioavailable dual MNK1/2 and BCR-ABL1 inhibitor with IC50 of 20/10/200/10 nM for Abl T315I/ wt Abl/MNK1/MNK2, respectively.
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DC21336 MNKI-8e
MNKI-8e (MNK inhibitor 8e) is a potent, selective MNK inhibitor that inhibits Mnk2 with Ki of 0.37 uM, displays >34-fold and 4-fold over CDK2 (Ki>10 uM) and CDK9 (Ki=1.66 uM).
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DC21338 MNKI-85
MNKI-85 is a potent and selective Mnk2 inhibitor with Ki of 31 nM, displays no inhibitory activities against Mnk1, CDK2A, CDK9T, and CDK4D.
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DC21337 MNKI-19
MNKI-19 is a potent and dual-specific Mnk inhibitor with Ki of 186 nM and 68 nM for Mnk1 and Mnk2, respectively.
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DC20463 MNK inhibitor 9
MNK inhibitor 9 is a potent, selective MAPK-interacting kinase (MNK1 and MNK2) inhibitor with IC50 of 3 nM for both, with no activity aginst CDK1/2 (IC50>25 uM).
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