Novel BBB-permeable substrate of pyrilamine-sensitive proton-coupled organic cation antiporter (PYSOCA), acting as a selective class I HDAC inhibitor

Novel KMD5A inhibitor

Novel highly potent agonist of the apelin receptor (APJ) receptor (APJ cAMP EC50: human 0.023nM; rat 0.024nM; dog 0.030nM; monkey 0.080nM)

Natural phytotoxin, inducing monopolar spindle formation and suppressing proliferation of cancer cells

Novel inhibitor of the PyrD protein (a dihydroorotate dehydrogenase (DHODase) involved in pyrimidine biosynthesis), suppressing bacterial cytotoxicity, biofilm formation and antibiotic resistance

Novel inhibitor of p53-MDM2 interaction

Bacterial siderophore, acting as an iron-chelating growth promoter for Pseudomonas aeruginosa

Novel suppressor of cancerous cell growth and proliferation

Novel potent inhibitor of collagen prolyl-4-hydroxylases (CP4H)

Inhibitor of cell death induced by oxidative stress and inhibitor of AB1-40 aggregation induced by Cu2+ ion

Novel selective FGF14:Nav1.6 PPI modulator

Novel Plasmodium vivax Hypoxanthine-Guanine Phosphoribosyltransferase Inhibitor

Novel potent anticancer agent, disturbing microtubule formation at the centrosomes and inhibiting the growth of tumors dose-dependently in the HCT116 human colon cancer xenograft model in vivo

Novel potent and selective CHEK2>Chk2 inhibitor

Novel Grp94-selective inhibitor PU-WS13 biotin probe

Natural heat shock protein 90 (Hsp90) inhibitor, potentiating the echinocandin drug caspofungin in caspofungin-resistant fungal pathogens, blocking the induction of caspofungin-responding genes required for the adaptation to cell wall stress through the c

Dual inhibitor of PDE3 and PDE4

Novel specific Hsp90b1 inhibitor

Hsp90α- and Hsp90ß-selective inhibitor

Novel specific inhibitor of tumor Hsp90

Hsp90α- and Hsp90ß-selective inhibitor

Novel thermally activated delayed fluorescence (TADF) molecule that exhibits high external quantum efficiency (EQE) in non-doped organic light-emitting diodes (OLEDs) at high luminescence

Novel PTEN-like mitochondrial phosphatase PTPMT1 inhibitor

Novel non-competitive potent and selective inhibitor of protein tyrosine phosphatase 1B (PTP1B)

Novel NIR fluorescent probe for the detection of Aβ oligomers

Unique promoter of SMN2 exon 7 splicing, acting by directly stimulating splicing of exon 7

Novel Potent Multi-target PTK Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis (IPF)

Novel Inhibitor of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer

Novel Inhibitor of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer

Novel Brk/PTK6 kinase inhibitor