Echinocystic acid  a pentacyclic triterpene isolated from the fruits of Gleditsia sinensis Lam, has potent antioxidant, anti-inflammatory and anti-tumor properties.

PD166285 (PD 0166285) is a broad-spectrum receptor tyrosine kinase (RTK) inhibitor that inhibits PDGFR-β, EGFR, and FGFR1 and c-Src with IC50 of 7-85 nM.

Trelagliptin(SYR-472) is a long acting dipeptidyl peptidase-4 (DPP-4) inhibitor that is being developed for the treatment of type 2 diabetes (T2D).

Argireline, also known as Acetyl Hexapeptide-3, is a newer ingredient in skincare, ideal for maturing skin and diminishing the appearance of wrinkles. Argireline is the brand name of Acetyl Hexapeptide-8, a molecule formed principally of 6 amino acids (which in a row are called a peptide). It is synthetically produced in a lab, but there are no indications of any degree of toxicity and it is one of our favorite compounds for maturing skin.

Zoledronic acid monohydrate(CGP 42446; ZOL 446) is an activator of protein kinase C with apoptotic effects on multiple myeloma cell lines. It inhibited proliferation of human foetal osteoblastic cell line (hFOB) with an IC50 of 40 uM.

A synthetic benzylamine antifungal that inhibits the synthesis of ergosterol by inhibiting squalene epoxidase.

CNX-2006 is a novel irreversible mutant-selective EGFR inhibitor with IC50 of < 20 nM, with very weak inhibition at wild-type EGFR.

Quetiapine fumarate is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression.

Entecavir hydrate belongs to the family of medicines called antivirals.

Efaproxiral Sodium is a synthetic allosteric modifier of hemoglobin, used for brain metastases originating from breast cancer.

Efinaconazole(KP-103) is a novel triazole antifungal drug currently under development as a topical treatment for onychomycosis.

EL-102 is a dual-inhibitor of apoptosis and angiogenesis, and exerts its action though the inhibition of Hif1 alpha induced hypoxic signalling pathways and induction of the Caspase 3/7 apoptotic cascade.

Eleclazine(GS-6615) is a selective late sodium current inhibitor.

ELN484228 is a blocker of α-synuclein which is a key protein in Parkinson’s disease.

ELQ300 is a novel inhibitor of the mitochondrial cytochrome bc1 complex (complex III in the electron transport chain).

Elvitegravir (EVG) is a drug used for the treatment of HIV infection. It acts as an integrase inhibitor.

EMA400 is a potent and highly selective AT2R antagonist.

EMICORON is a novel G-quadruplex (G4) ligand showing high selectivity for G4 structures over the duplex DNA, causing telomere damage and inhibition of cell proliferation in transformed and tumor cells.

ENOblock(AP-III-a4) is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 uM); inhibit cancer cell metastasis in vivo.

Ent-kaurene is a tetracyclic diterpene consisting of ent-kaurane, where the 6-methyl group is replaced by methylene. It derives from a hydride of an ent-kaurane.

EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.

Erianin, often used as an antipyretic and analgesic agent, could inhibit IDO-induced tumor angiogenesis.

ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50s of 0.82 μM, 3 μM for ERK5 and ERK5 MEF2D, respectively.

Esonarimod (KE-298) is a new antirheumatic drug.

ETH 157（Sodium ionophore II）is a neutral ionophore for liquid-membrane electrodes of high selectivity for Na+.

Etofenamate is a non-steroidal anti-inflammatory drug used for the treatment joint and muscular pain.

ETP-46464 is a cell-permeable quinoline-containing heterotricyclic compound that acts as a potent inhibitor against mTOR, ATR, DNA-PK, PI 3-Kα, and ATM (IC50= 0.6, 14, 36, 170, and 545 nM, respectively).

AS2717638 is an oral active lysophosphatidic acid receptor 5 (LPA5) antagonist in rodents. AS2717638 also significantly improves PGE2-, PGF2α-, and AMPA-induced allodynia.

Aplaviroc, also known as AK-602; GW-873140; GW873140A; ONO-4128, is a CCR5 entry inhibitor for the potential treatment of HIV infection. Aplaviroc (GW873140) binds specifically to human cellular CC chemokine receptor 5 (CCR5) and demonstrates potent anti-human immunodeficiency virus activity in vitro in the subnanomolar range. In vitro studies show that aplaviroc selectively inhibits the binding of a particular monoclonal antibody, 45531, to CCR5.

Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure.