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Cat. No. Product Name Field of Application Chemical Structure
DC35187 t-Boc-N-Amido-PEG6-propargyl
t-Boc-N-Amido-PEG6-propargyl is a PEG derivative containing a propargyl group and Boc-protected amino group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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DC36781 Oxethazaine
Oxethazaine is a surface anesthetic used mainly orally in chronic gastritis & heartburn to analgize the gastric mucosa.
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DC35181 N-methyl-N-(t-Boc)-PEG4-acid
N-methyl-N-(t-Boc)-PEG4-acid is a Boc PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC35236 Bromoacetamido-PEG4-NHS ester
Bromoacetamido-PEG4-NHS ester is a PEG derivative containing a bromide group and an NHS ester. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
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DC35158 t-Boc-N-amido-PEG1-NHS ester
t-Boc-N-amido-PEG1-NHS ester is a Boc-protected PEG linker. The Boc group can be deprotected under acidic conditions to generate a free amine group. PEG Linkers may be useful in the development of antibody drug conjugates (ADCs).
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DC34892 Amino-PEG1-t-butyl ester
Amino-PEG1-t-butyl ester is a PEG derivative containing an amino group with a t-butyl protected carboxyl group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC35025 Benzyl-PEG2-azide
Benzyl-PEG2-azide is a PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC35763 NH-bis(PEG3-azide)
NH-bis(PEG3-azide) is a PEG derivative containing an amino group with two azide groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls. The azide groups enable PEGylation via Click Chemistry.
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DC35782 N-Boc-N-bis(PEG3-azide)
N-Boc-N-bis(PEG3-azide) is a branched PEG derivative with two terminal azide groups and a Boc protected amino group. The azide groups enable PEGylation via Click Chemistry. The protected amine can be deprotected by acidic conditions.
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DC38059 Loratadine specified impurity F
Loratadine specified impurity F is a fluorinated analog of Loratadine, which is a nonsedating-type histamine H1-receptor.
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DC34311 S-Fcme
S-Fcme is a multidrug resistance transporter activator. It acts by stimulating the multidrug resistance transporter ATPase activity and competing for drug binding.
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DC34499 LEE011 analog
CDK4-IN-1 is a selective inhibitor of cyclin-dependent kinase 4.
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DC34666 Pleuromulin
Pleuromulin is an antibiotic that derives from a class of antibacterials with different mechanisms of action from clinically used antibacterials. This is of interest due to the rapid onset of resistance to most antibacterial drugs. It has been shown that there is rarely cross-resistance between pleuromutilin derivatives and other antimicrobial agents.
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DC34398 Ro 41-0960
Ro 41-0960 is a reversible and orally-active COMT-inhibitor.
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DC33994 Hexaethylene glycol phosphoramidite
Spacer phosphoramidite 18 (hexaethylene glycol phosphoramidite) is an amidite reagent for oligonucleotide synthesis. It provides a long hydrophilic linker that can be used for the synthesis of Scorpion-type qPCR probes, for spacing biotin from oligo strand, and for other applications requiring spatial separation of modifier and oligo
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DC35228 m-PEG9-bromide
m-PEG9-bromide is a PEG derivative. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35226 m-PEG6-bromide
m-PEG6-bromide is a PEG derivative. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC34017 MS-1020
MS-1020 is a JAK3 and STAT3 inhibitor. MS-1020 potently inhibits persistently-active STAT3 in a cell type-specific manner. MS-1020 selectively blocks constitutively-active JAK3 and consistently suppressed interleukin-2-induced JAK3/STAT5 signalling.
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DC35513 T-Butyl 1,3-dihydroxypropan-2-ylcarbamate
T-Butyl 1,3-dihydroxypropan-2-ylcarbamate is a PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC35751 Azido-PEG3-CH2CO2Me
Azido-PEG3-CH2CO2Me is a crosslinker containing an azide group a methyl ester. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35046 Biotin-PEG3-NHS ester
Biotin-PEG3-NHS ester is PEG derivative containing a biotin group and an NHS ester group. The NHS group reacts specifically and efficiently with lysine and N-terminal amino groups at pH 7-9 to form stable amide bonds. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC34540 Ro317549 Monohydrate
Ro-31-7549 Monohydrate is a cell permeable, reversible, selective protein kinase C (PKC) inhibitor.
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DC35478 Tr-PEG5
Tr-PEG5 is a PEG derivative.
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DC35527 m-PEG12-acid
m-PEG12-acid is a PEG derivative containing a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC36074 AR-C133913XX
Ticagrelor metabolite M5, also known as AR-C133913XX, is a metabolite of Ticagrelor which is the first reversible oral P2Y12 receptor antagonist. Ticagrelor provides faster and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).
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DC35568 m-PEG12-aldehyde
m-PEG12-aldehyde is a PEG derivative containing an aldehyde group. Aldehyde is reactive to hydrazide and aminooxy groups which are commonly used in biomolecular probes for labeling and crosslinking carbonyls (oxidized carbohydrates). The hydrophilic PEG spacer increases solubility in aqueous media.
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DC36075 A-hydroCort
Hydrocortisone sodium succinate is a glucocorticoid which is used to alleviate allergic reactions, particularly those of the skin and gums.
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DC35618 diethyl 8-bromooctylphosphonate
diethyl 8-bromooctylphosphonate is a non-PEG Linker.
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DC37363 Picrotoxin
Picrotoxin, also known as cocculin, is a poisonous crystalline plant compound. Due to its interactions with the inhibitory neurotransmitter GABA, picrotoxin acts as a stimulant and convulsant.
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DC34204 Pitofenone hydrochloride
Pitofenone hydrochloride is an antispasmodic agent. It acts as a potent inhibitor of acetylcholinesterase activity.
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