WR-1065 Dihydrochloride is a metabolite of Amifostine.

CY5 is a photoswitchable fluorescent labeling reagent.

Deacetylasperulosidic Acid is a natural glycoside which demonstrates antioxidant activity in vivo and in human trials.

Pregnenolone-carbonitrile is an agonist of the rodent pregnane X receptor (PXR), inducing cytochrome P450.

VI-16832 is a broad spectrum type-I kinase inhibitor.

MNF, also known as 3,4-MNF, is an antagonist of the aryl hydrocarbon receptor (AhR). MNF reduces UVR-mediated immunosuppression and induces Tregs in murine contact hypersensitivity (CHS).

Amthamine dihydrobromide is a histamine H2 agonist.

Iprovalicarb is a fungicide specific to oomycetes.

Tyrphostin AG957 is a tyrosine kinase inhibitor, selectively inhibiting human p210 tyrosine kinase activity.

NeuroSensor 521 is a fluorescent turn-on sensor. It acts by binding catecholamines such as dopamine and norepinephrine more tightly than other biogenic amines such as glutamate and does not interact with secondary amines such as epinephrine.

TFMB-(R)-2-HG is a cell membrane-permeable version of (R)-2-HG that acts as a promoter of leukemogenesis, dose-dependently and passage-dependently blocking differentiation.

TC-E 5002 is a selective histone demethylase KDM2/7 subfamily inhibitor.

KT185 is the first orally-active ABHD6-selective inhibitor. It displays excellent selectivity against other brain and liver serine hydrolases in vivo.

Adenosine N1-oxide is an inhibitor of secretion of inflammatory mediators. It acts by suppressing pro-inflammatory cytokine secretion.

UNC2327 is an allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3).

Oxolinic acid is an inhibitor of DNA-gyrase (topoisomerase II). It acts by inhibiting dopamine reuptake.

Digitoxigenin is a precursor of cardiac glycosides. It acts by targeting the metastatic uveal melanoma gene signature.

Bacitracin is an antibiotic. It has been shown to disrupt gram positive bacteria by interfering with cell wall and peptidoglycan synthesis.

Strychnine Hydrochloride is a neurotoxin that acts as an antagonist of glycine and acetylcholine receptors.

Leelamine, also known as NSC-2955, is a selective and potent inducer of hepatic cytochrome P450 2B activity. It is also an inhibitor of intracellular cholesterol transport.

YM511 is a non-steroidal selective aromatase inhibitor. YM511 may be useful in the treatment of estrogen-dependent cancers without affecting serum levels of other steroid hormones.

gamma-Tocotrienol is one of the four types of tocotrienol, a type of vitamin E. gamma-Tocotrienol is a radioprotector, antioxidant, and shows antitumor and antihypertensive effects in vivo.

Carboxy-PTIO is a NO scavenger. Streptozotocin (STZ) induced diabetes (type I) in rats is preventable using a simultaneous equimolar injection of carboxy-PTIO.

PACA, also known as N-Propargyl Caffeamide, potentiates NGF-induced neurite outgrowth and attenuates 6-hydroxydopamine neurotoxicity in neuronal culture. Insufficient production of nerve growth factor (NGF) is implicated in Parkinson's disease (PD).

Sophoridine is an antiviral against Coxsackievirus B3. Sophoridine works by regulating cytokine expression which may represent a potential therapeutic agent for viral myocarditis. Sophoridine also has anti-tumor and anti-inflammatory properties.

Phosphoramidite for the synthesis of oligonucleotides with 5'-terminal alkyne for Click Chemistry. This alkyne amidite has several advantages over 5’-hexynyl phosphoramidite, 5'-butynyl-CEP, and other 5'-terminal alkyne phosphoramidites. First, it is solid compound which is easier to handle and dispense. And due to its structure, it is also more stable in solution, and has longer shelf life

Cyanine5.5 dye, free acid form, unactivated. The dye can be considered non-reactive for most applications. It can be used as a control or reference sample, and for instrument calibration.

Cyanine5 maleimide is a mono-reactive dye which selectively couples with thiol groups (for example, with cysteines in peptides and proteins) to give labeled conjugates. Cyanine5 is an analog of Cy5?, a common fluorophore which is compatible with various instrumentation like microscopes, imagers, and fluorescence readers. For the labeling of antibodies and sensitive proteins we recommend to use the water soluble sulfo-Cyanine5 maleimide.

Water soluble, amino-reactive sulfo-Cyanine3 NHS ester. Efficiently labels proteins and peptides in purely aqueous solution, without need for organic co-solvent. Ideal for proteins with low solubility, and proteins prone to denaturation.This product is an analog of Cy3 NHS ester. Sulfo-Cyanine3 NHS ester replaces Cy3, Alexa Fluor 546, and DyLight 549 for all applications.

The structure of Cyanine7 features rigidized design of central polymethyne chain. This molecular reinforcement allows to increase quantum yield by 20% compared with parent structure, increasing fluorescence brightness. NIR fluorophores can be used to take advantage of near infrared window of biological tissues - increased transparency of tissues in this spectral region allows to carry out in vivo imaging. This reagent can be utilized to produce Cyanine7-labeled biomolecules for subsequent use in various in vivo research, and drug design related experiments.