Cat. No. | Product Name | Field of Application | Chemical Structure |
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DC33550 | YD2 |
YD2 is a porphyrin sensitizer. YD2 is a useful material for making solar cell. Cosensitization of YD2-o-C8 with another organic dye enhances the performance of the device, leading to a measured power conversion efficiency of 12.3% under simulated air mass 1.5 global sunlight.
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DC33549 | RQ-00311651 |
RQ-00311651 is a novel T-type Ca2+ channel blocker, in distinct rodent models for neuropathic and visceral pain. RQ-00311651 strongly suppressed T currents when tested at holding potentials of -65 ~ -60 mV, but not -80 mV, in the Cav3.1- or Cav3.2-expressing cells. RQ-00311651 also inhibited high K-induced Ca signaling in those cells.
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DC33547 | ABH free base |
ABH , also known as Amino-2-Borono-6-Hexanoic Acid, is an arginase inhibitor, enhancing both male and female sexual arousal responses.
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DC33545 | SSD114 HCl |
SSD114 is a GABAB positive allosteric modulator. SSD114 potentiated GABA-stimulated [35S]GTPγS binding to native GABAB receptors, whereas it had no effect when used alone. SSD114, a molecule with a different chemical structure compared to known GABAB PAMs, is a novel GABAB PAM with potential usefulness in the GABAB-receptor research field.
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DC33542 | D-AP7 |
D-AP7 is a specific NMDA antagonist and is the more active form of DL-AP7. D-AP7 enhanced motility, exhibited anxiogenic-like effect and impaired consolidation in passive avoidance.
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DC33541 | Calpain Inhibitor VI |
SJA6017, also known as Calpain Inhibitor VI, is a calpain inhibitor (calpain-1; IC50 = 7.5 nM) and m-calpain (calpain-2; IC50 = 78 nM). It also inhibits cathepsins B and L (IC50s = 15 and 1.6 nM, respectively). Treatment with SJA6017 reduces apoptotic cell death, preserves spinal cord tissue and improves functional outcome. Treating calpain-induced apoptosis with this agent may be a feasible therapeutic strategy for patients with spinal cord injury.
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DC33540 | CU-CPT22 |
CU-CPT22 is the first probe for the complex between toll-like receptors TLR1 and TLR2. CU-CPT22 binds at the interface of TLR1 and TLR2 (IC50 = 0.58 μM).
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DC33539 | BTT-3033 |
BTT-3033 is a α2β1 integrin inhibitor. BTT-3033 blocks platelet attachment under flow (90 dynes/cm(2)). The action of BTT-3033, unlike that of BTT-3034, was dependent on Tyr-285.
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DC33538 | Monocrotophos |
Monocrotophos is an organophosphate insecticide that blocks monoamine oxidase and acetylcholinesterase.
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DC33536 | azF |
4-Azido-L-phenylalanine, also known as azF, is a genetically-encoded molecular probe. azF is used to study GPCRs in their native cellular environment or under detergent solubilized conditions.
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DC33534 | LPA5-IN-4 |
LPA5-IN-4 is the first non-lipid, small-molecule inhibitor for LPA5/GPR92, specifically inhibiting LPA-mediated platelet activation in vitro.
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DC33533 | CYP3cide |
PF-04981517, also known as CYP3cide, is a potent and selective time dependent inactivator of Cytochrome P450 3A4 (CYP3A4). CYP3cide is a very useful tool for understanding the relative roles of CYP3A4 versus CYP3A5 and the impact of CYP3A5 genetic polymorphism on a compound's pharmacokinetics.
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DC33532 | GQ-16 |
GQ-16 is an effective inhibitor of Cdk5-mediated phosphorylation of PPARγ. GQ-16 improves glucose tolerance and insulin sensitivity in mouse models of obesity and diabetes without inducing weight gain or edema.
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DC33531 | J1038 |
J1038 is a novel Inhibitor of Histone Deacetylase 8 (HDAC8).
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DC33530 | HLI373 |
HLI373 is a water-soluble inhibitor of Hdm2. HLI373 is effective in inducing apoptosis of several tumor cells lines that are sensitive to DNA-damaging agents. HLI373 could serve as a potential lead for developing cancer therapeutics based on inhibition of the ubiquitin ligase activity of Hdm2.
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DC33529 | Histomon |
Nifursol is a livestock feed additive and antiobiotic used to prevent the growth of histomonas.
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DC33528 | D-(+)-Neopterin |
D-(+)-Neopterin is an endogenous pteridine metabolite of GTP used as an endogenous biomarker of cellular immune response and oxidative stress.
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DC33527 | beta-Naphthoflavone |
beta-Naphthoflavone is a AhR agonist and antioxidant. It inhibits cigarette smoked-induced DNA damage and tumor development and induces cell cycle arrest in breast cancer cells.
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DC33526 | Benil |
Naphazoline nitrate is α1-Adrenergic receptor agonist used to treat congestion and ocular pathologies. It also induces autophagy and necrotic cell death in erythroleukemia cells and inhibits erythroid differentiation.
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DC33525 | Albalon Liquifilm |
Naphazoline HCl is an α1-Adrenergic receptor agonist used to treat congestion and ocular pathologies. It also induces autophagy and necrotic cell death in erythroleukemia cells and inhibits erythroid differentiation.
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DC33524 | Nadifloxacine |
Nadifloxacin is a bacterial DNA gyrase inhibitor used to treat acne vulgaris. It inhibits Proponibacterium-stimulated cytokine expression and decreases production of oxidative radicals by neutrophils.
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DC33523 | Myclobutanil |
Myclobutanil is a 14-α demethylase inhibitor that inhibits ergosterol synthesis and fungal cell wall formation. It also weakly inhibits testosterone production.
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DC33522 | Moniliformin |
Moniliformin is a mycotoxin and potential dehydrogenase inhibitor found in Fusarium. It decreases collage synthesis, suppresses endocytosis, and may damage myocardial tissue.
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DC33521 | Coban 45 |
Monensin sodium is an ionophore and inhibitor of autophagy commercially used in livestock feed. It inhibits autophagy, interfering with the fusion of the autophagosome and the lysosome.
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DC33520 | BW-B 1090U |
Mivacurium chloride is a non-depolarizing NMJ blocker and nAChR antagonist used as an anesthetic. It inhibits skeletal muscle contractility and prevents atrial fibrillation.
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DC33519 | Andergin |
Miconazole nitrate is an 14-α demethylase inhibitor and potential glucocorticoid receptor antagonist that inhibits ergosterol synthesis and fungal cell wall formation. It is used to treat fungal infections and is especially active against Candida. It also decreases expression of HIF-1α and VEGF in breast cancer and glioma cells.
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DC33518 | Kavatin |
Methysticin is found in Piper methysticum (kava plant). It inhibits activation of NF-χB in lung adenocarcinoma tissue, activates Nrf2 in neurons and astroglia, decreases peak amplitude of voltage-gated Na+ channels in hippocampal neurons, and suppresses growth of Fusarium, Trichoderma, and Colletotrichum.
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DC33517 | 7-Methyl-6-mercaptopurine |
7-Methyl-6-mercaptopurine is a 6-mercaptopurine derivative and inhibitor of PRPP amidotransferase used to treat autoimmune diseases, leukemia,s and lymphomas. It inhibits IMP metabolism, preventing the synthesis of purines, DNA and RNA.
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DC33516 | Methyiin |
NSC-226572, also known as Alanine, 3-(methylsulfinyl)-, L-, pyrolyzate, S-methyl-L-cysteine-S-oxide; S-Methylcysteine sulfoxide, is a synthetic analog of alliin found in cruciferous vegetables including cabbage, turnip, cauliflower, and kale. NSC-226572 is converted through alliinase activity into a volatile thiosulfinate.
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DC33515 | S-Methyl-L-cysteine |
S-Methylcysteine is an antioxidant found in Brassicaceae family plants. It decreases oxidative stress and inhibits oil drop formation in white pre-adipose tissue.
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