Spiperone HCl is a 5-HT2A serotonin and selective D2-like dopamine receptor antagonist.

FPL-55712 is a CysLT1 leukotriene receptor antagonist.

PPDA is a subtype-selective NMDA receptor antagonist that preferentially binds to NR2C/NR2D-containing receptors.

A3 HCl is an inhibitor of PKA, PKC, and casein kinase I and II, and MLCK.

Amperozide HCl is a 5-HT2/D2 antagonist, inhibiting nomifensine-induced hyperlocomotion and human FAAH.

SC-53116 HCl is a psychoactive agent, increasing in production of serotonin in central nervous system tissue.

RP-106 is a selective, potent, ATP-competitive inhibitor of CDK1/cyclin B, CDK5/p25, and GSK-3.

(-)-MDO-NPA HCl is an orally effective long-acting agent active at central dopamine receptors, and analogous aporphines.

U-69593 is a selective kappa opioid receptor agonist.

BCI hydrochloride is an allosteric inhibitor of Dusp6, acting within the phosphatase domain to prevent the catalytic stimulation of phosphatase activity induced by ERK2 substrate binding.

SB-505124 HCl is an inhibitor of activin receptor-like kinase (ALK) 5.

P18IN011 is a novel p18(INK4C) inhibitor.

NMIA, also known as N-Methylisatoic Anhydride, is an RNA SHAPE reagent.

Kukoamine B Mesylate is potentially for the treatment of sepsis. Kukoamines are a series of bioactive phytochemicals conjugated by a polyamine backbone and phenolic moieties. Treatment with KuB prior to H2O2 exposure effectively increased the cell viability, and restored the mitochondria membrane potential (MMP). Furthermore, KuB enhanced the antioxidant enzyme activities of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) and decreased the malondialdehyde (MDA) content. Moreover, KuB minimized the ROS formation and inhibited mitochondria-apoptotic pathway, MAPKs (p-p38, p-JNK, p-ERK) pathways, but activated PI3K-AKT pathway.

Sinafloxacin Mesylate is a quinolone antibiotic potentially for the treatment of bacterial infections. There is a strong interaction between sinafloxacin and BSA. From thermodynamic coordination it can be judged that the binding force between sinafloxacin and BSA is mainly electro-static force. The effect of sinafloxacin on the conformation of BSA was analyzed by synchronous fluorescence spectrometry and three-dimensional fluorescence spectrometry. The emission maximum of tyrosine residues does not show a significant shift, while the small blue shift of tryptophan residues indicates that the hydrophobicity of microenvironment was increased. In addition, in the plasma, there are some metal ions, which can participate in many important vital actions and affect the reactions of the drugs with the serum albumins.

Forodesine is a transition-state analog inhibitor of purine nucleoside phosphorylase.

Olodanrigan, also known as EMA401, is a novel orally available and highly selective angiotensin II type 2 receptor (AT2R) antagonist.

AT2 Agonist C21 is the first potent and selective agonist of angiotensin AT2 receptors, preventing endothelial inflammation and leukocyte adhesion in vitro and in vivo. AT2 Agonist C21 prevents cognitive decline after permanent stroke in aged animals-A randomized double- blind pre-clinical study. AT2 Agonist C21 attenuates pulmonary inflammation in a model of acute lung injury. AT2 Agonist C21 attenuates the Progression of Lung Fibrosis and Pulmonary Hypertension in an Experimental Model of Bleomycin-Induced Lung Injury.

CAY10471, also known as TM30089, is a potent and selective long-lasting antagonist of CRTH2. Cat#527092 is a + rotation. isomer (note sure it is a R-isomer or S-isomer).

CGP12177A is a partial agonist of ?3-adrenoceptors and antagonist of ?1- and ?2-adrenoceptor.

NPPB is a voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR) channel blocker.

Isoxepac, also known as Olopatadine USP Related Compound C, is a non-steroidal anti-antiphlogistic agent and analgesic.

Nortropine Hydrochloride is a secondary metabolite of tropine derivative drugs, such as atropine and benztropine.

Quinocetone is an animal growth promoter; Antimicrobial agent.

Salbutamol Sulfate is a short-acting beta-2 adrenergic agonist.

Pentamidine is an antiprotozoal and antifungal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor groove of DNA, thereby interfering with DNA replication.

Ceftiofur Hydrochloride is a broad-spectrum, third-generation cephalosporin antibiotic, binding to and inactivating penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall.

Rabeprazole is an inhibitor of H(+)-K(+)-exchanging atpase in gastric parietal cells.

X-alpha-Gal is a substrate for alpha-galactosidase, differentiating alpha-galactosidase-positive strains of yeast.

Nequinate is an anticoccidial agent, preventing coccidiosis and developing immunity against five different species of Eimeria.