AZ-PFKFB3-67 is a novel potent and selective PFKFB3 inhibitor.

Z-LLNle-CHO, also known as gamma-Secretase Inhibitor I, is a cell permeable inhibitor of gamma-secretase, inducing apoptosis of human glioblastoma tumor-initiating cells by proteasome inhibition and mitotic arrest response.

FKGK11 is a novel potent inhibitor of GVIA iPLA2 with little or no inhibition against GIVA cPLA2 (XI(50) = 0.0073 and >0.91, respectively).

HUN85199, also known as B-Raf inhibitor 1 dihydrochloride, is a novel potent and selective B-Raf inhibitor. HUN85199 has CAS#1191385-19-9, was first reported in Journal of Medicinal Chemistry (2009), 52(20), 6189-6192. It has no code name. For the convenience of scientific communication, we name it as HUN85199 by using CAS# ahdn inchi key as proposed by Hodoodo Chemical Nomenclature (see https://hodoodo.com/hodoodo-chemical-nomenclature).

Sulbactam pivoxil, also known as CP-47904 and Pivsulbactam, is an irreversible inhibitor of β-lactamase; it binds to the enzyme and does not allow it to degrade the antibiotic.

Sudoxicam is a nonsteroidal anti-inflammatory drugs (NSAIDs) from the enol-carboxamide class.

Sulfamonmethoxine is a competitive inhibitor of dihydropteroate synthetase, blocking the synthesis of folic acid.

MHY908 is a novel inhibitor of melanogenesis, potently inhibiting mushroom tyrosinase activity in a dose-dependent manner.

CP-944629 is a novel, potent, and selective p38alpha inhibitor.

BMS-770767 is a novel inhibitor of 11-betahydroxysteroid dehydrogenase type I (11?-HSD1).

Sofalcone is an oral gastroprotective, gastrointestinal medication. It is a synthetic analog of sophoradin.

HA-1004 is an inhibitor of PKA, cGKI, PKC, MYLK, and calcium channel protein.

Pyrabactin is a plant growth inhibitor, acting as a seed-selective abscisic acid (ABA) agonist; Novel PYL agonist.

Triclabendazole is an anthelmintic and fasciolicidal, binding to beta-tubulin and preventing the polymerization of the microtubules of which they are part. Studies in vitro and/or in infected animals suggest that triclabendazole and its active metabolites (sulfoxide and sulfone) are absorbed by the tegument of the immature and mature worms, leading to a decrease of the resting membrane potential, inhibition of tubulin function as well as protein and enzyme synthesis. These metabolic disturbances are associated with inhibition of motility, disruption of the surface as well as ultrastructure that includes inhibition of spermatogenesis and vitelline cells.

Myoseverin is an inducer of the reversible fission of multinucleated myotubes into mononucleated fragments, affecting the expression of a variety of growth factor, immunomodulatory, extracellular matrix-remodeling, and stress response genes, consistent with the activation of pathways involved in wound healing and tissue regeneration.

SB 224289 is a selective 5-HT1B receptor antagonist (pKi = 8.2). SB 224289 displays > 60-fold selectivity over 5-HT1D, 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A and 5-HT2C receptors in radioligand binding and functional assays. SB 224289 is a centrally active following oral administration in vivo.

Suprafenacine is a novel cell permeable selective inhibitor of cancer cell proliferation, binding microtubules at the colchicine-binding site and inhibiting polymerization, leading to G2/M cell cycle arrest and cell death via a mitochondria-mediated apoptotic pathway.

TBMP is a novel inhibitor of the viral envelope protein hemagglutinin (HA)-mediated entry.

Ro 24-7429 is a Tat antagonist. Ro 24-7429 blocks the action of the HIV tat protein and is an analog of Ro 5-3335.

Aminotadalafil is an analog of Tadalafil as a phosphodiesterase type 5 (PDE-5) inhibitor.

2-DG is an inhibitor of glycolysis via its actions on hexokinase, the rate limiting step of glycolysis.

Cyclo-L-Trp-L-Trp is a broad spectrum antifungal, inducing a high degree of acetylation of histones.

FSB is a highly fluorescent amyloid-specific dye.

Quinaprilat is the active metabolite of quinapril, an angiotensin-converting enzyme inhibitor (ACE inhibitor) used in the treatment of hypertension and congestive heart failure.

Propranolol Hydrochloride is a non-cardioselective beta-adrenergic antagonist. It has been shown to be active against disorders including cardiac infarcations, arrhythmias, hypertension, and hyperthyroidism.

Talniflumate is a novel potent and selective inhibitor of core mucin-synthesizing enzyme GCNT3 (core 2b-1,6 N-acetylglucosaminyltrans-ferase).

Pyrazoloacridine is an investigational nucleic acid binding agent that inhibits the activity of topoisomerases 1 and 2. Pyrazoloacridine was a phase II clinical study to determine the efficacy and toxicities of PZA in patients with metastatic breast cancer (MBC)Pyrazoloacridine appears to intercalate into DNA and inhibit RNA synthesis, DNA synthesis, and the activities of topoisomerases I and II, thereby causing cytotoxicity.

Danofloxacin is a fluoroquinolone antibiotic used in veterinary medicine.

Propoxur is a carbamate insecticide. Propoxur is a non-systemic insecticide with a fast knockdown and long residual effect used against turf, forestry, and household pests and fleas.

Propanidid, also known as Sombrevin, is a short-acting phenylacetate general anesthetic.