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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC12447 | BCL6 PROTAC 15 |
BCL6 PROTAC 15 is a novel B-cell lymphoma 6 (BCL6) PROTAC, significantly degrade BCL6 in a number of DLBCL cell lines, but neither BCL6 inhibition nor degradation selectively induces marked phenotypic response.
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| DC12446 | BCL6 inhibitor 14 |
BCL6 inhibitor 14 is a potent BCL-6 inhibitor with FRET IC50 of 63 nM..
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| DC20758 | BCI-137 |
BCI-137 is a chemical compound able to compete with Argonaute 2 miRNAs binding, binds to Ago2 with Kd of 126 uM.
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| DC20757 | BC-23 |
BC-23 (NSC 45382) is a novel inhibitor of β-catenin/Tcf4 interaction with IC50 of 1.7 uM.
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| DC21401 | BC-21 |
BC-21 (NSC 109268) is a novel small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 6.55 uM.
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| DC20755 | BC-1485 |
BC-1485 is a first-in-class, small molecule inhibitor of FIEL1 (Fibrosis-inducing E3 ligase 1) that exhibits potent activity toward disrupting FIEL1-directed PIAS4 ubiquitination.
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| DC12280 | BB-Cl-Amidine |
BB-Cl-Amidine is a peptidylarginine deminase (PAD) inhibitor.
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| DC22017 | BAY-826 |
BAY-826 (BAY826) is a novel selective, highly potent, orally available TIE-2 inhibitor (dissociation constant=1.6 nM).
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| DC22016 | BAY-7598 |
BAY-7598 (BAY7598) is a potent, selective MMP12 inhibitor..
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| DC20749 | BAY-707 |
BAY-707 is a highly potent, selective and substrate-competitive inhibitor of MTH1 (NUDT1) with IC50 of 2.3 nM.
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| DC12088 | BAY-678 racemate |
BAY-678 racemate is a chemical probe candidate for Human Neutrophil Elastase (HNE).
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| DC11007 | BAY-524 |
BAY-524 (BAY524) is a potent, selective, ATP-competitive inhibitor of Bub1 kinase with IC50 of 450 nM.
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| DC22015 | BAY-386 |
BAY-386 (BAY386) is a potent, specific and reversible PAR-1 antagonist with IC50 of 10 nM (HEK cell) and binding IC50 of 56 nM, without affinity for PAR-4 (IC50>10 uM).
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| DC11006 | BAY-320 |
BAY-320 (BAY320) is a potent, selective, ATP-competitive inhibitor of Bub1 kinase with IC50 of 680 nM.
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| DC23816 | BAY-293 racemate |
BAY-293 racemate (BAY293 racemate) is a potent SOS1 inhibitor that disrupts the KRAS-SOS1 interaction with IC50 of 50 nM, the R-enantiomer (BAY-293) is the active form with IC50 of 21 nM, while the BAY-293 is less active (IC50=2,340 nM)..
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| DC23438 | BAY 60-6583 |
BAY 60-6583 (BAY606583) is a potent, selective adenosine A2B receptor agonist with EC50 of 2.83 nM (murine A2BR).
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| DC20748 | BAY 60-2770 |
BAY 60-2770 is an NO-independent activator of sGC (soluble guanylyl cyclase) with EC50 of 5.4 nM.
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| DC20747 | BAY 41-8543 |
BAY 41-8543 is an NO-independent sGC (soluble guanylyl cyclase) stimulator, inhibits collagen-mediated aggregation in washed human platelets (IC50=90 nM).
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| DC10291 | Bay 41-4109 less active enantiomer |
Bay 41-4109 less active enantiomer shows less activity than Bay 41-4109. BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM.
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| DC23386 | BAY 1238097 |
BAY 1238097 is a novel BET bromodomain inhibitor with IC50 of 50 nM, inhibits the interaction between BRD4, BRD3 or BRD2 and H4 with IC50 values of 63 nM, 609 nM and 2430 nM in the NanoBRET assay.
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| DC20750 | BAY 1143269 |
BAY 1143269 is a potent, selective, orally bioavailable inhibitor of MNK1 with enzyme IC50 of 40 nM at 2 mM ATP.
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| DC23719 | BAY 1024767 |
BAY 1024767 (BAY1024767) is a higly potent antagonist of androgen receptor (AR) wild-type (IC50=46 nM) and mutant forms located in the AR ligand-binding domain (LBD).
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| DC9562 | Balsalazide |
Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.
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| DCAPI1046 | Balofloxacin |
Balofloxacin
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| DC20740 | BAL30072 |
BAL30072 is a monocyclic beta-lactam antibiotic that shows potent activity against MDR Pseudomonas aeruginosa and Acinetobacter sp. Isolates with MIC90 of 8 and 4 ug/ml.
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| DCAPI1066 | Bacitracin zinc |
Bacitracin zinc
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| DC22011 | BAA473 |
BAA473 (BAA-473) is a bile acid analogue that functions as the first small molecule activator of the Pyrin inflammasome, induces secretion of IL18 in LPS-primed PBMCs.
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| DC22010 | B591 |
B591 (B-591) is a potent, specific pan-PI3K inhibitor with IC50 of 1.3/0.36/1.1/1.58 uM for PI3Kα/β/γ/δ, respectively.
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| DC12114 | B I09 |
B I09 is an IRE-1 RNase inhibitor, with an IC50 of 1230 nM.
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| DC23756 | Aβ polymerization stimulator O4 |
Aβ polymerization stimulator O4 is an orcein-related small molecule can drive polymerization of amyloid-β (Aβ).
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