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Cat. No. Product Name Field of Application Chemical Structure
DC12447 BCL6 PROTAC 15
BCL6 PROTAC 15 is a novel B-cell lymphoma 6 (BCL6) PROTAC, significantly degrade BCL6 in a number of DLBCL cell lines, but neither BCL6 inhibition nor degradation selectively induces marked phenotypic response.
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DC12446 BCL6 inhibitor 14
BCL6 inhibitor 14 is a potent BCL-6 inhibitor with FRET IC50 of 63 nM..
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DC20758 BCI-137
BCI-137 is a chemical compound able to compete with Argonaute 2 miRNAs binding, binds to Ago2 with Kd of 126 uM.
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DC20757 BC-23
BC-23 (NSC 45382) is a novel inhibitor of β-catenin/Tcf4 interaction with IC50 of 1.7 uM.
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DC21401 BC-21
BC-21 (NSC 109268) is a novel small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 6.55 uM.
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DC20755 BC-1485
BC-1485 is a first-in-class, small molecule inhibitor of FIEL1 (Fibrosis-inducing E3 ligase 1) that exhibits potent activity toward disrupting FIEL1-directed PIAS4 ubiquitination.
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DC12280 BB-Cl-Amidine
BB-Cl-Amidine is a peptidylarginine deminase (PAD) inhibitor.
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DC22017 BAY-826
BAY-826 (BAY826) is a novel selective, highly potent, orally available TIE-2 inhibitor (dissociation constant=1.6 nM).
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DC22016 BAY-7598
BAY-7598 (BAY7598) is a potent, selective MMP12 inhibitor..
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DC20749 BAY-707
BAY-707 is a highly potent, selective and substrate-competitive inhibitor of MTH1 (NUDT1) with IC50 of 2.3 nM.
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DC12088 BAY-678 racemate
BAY-678 racemate is a chemical probe candidate for Human Neutrophil Elastase (HNE).
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DC11007 BAY-524
BAY-524 (BAY524) is a potent, selective, ATP-competitive inhibitor of Bub1 kinase with IC50 of 450 nM.
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DC22015 BAY-386
BAY-386 (BAY386) is a potent, specific and reversible PAR-1 antagonist with IC50 of 10 nM (HEK cell) and binding IC50 of 56 nM, without affinity for PAR-4 (IC50>10 uM).
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DC11006 BAY-320
BAY-320 (BAY320) is a potent, selective, ATP-competitive inhibitor of Bub1 kinase with IC50 of 680 nM.
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DC23816 BAY-293 racemate
BAY-293 racemate (BAY293 racemate) is a potent SOS1 inhibitor that disrupts the KRAS-SOS1 interaction with IC50 of 50 nM, the R-enantiomer (BAY-293) is the active form with IC50 of 21 nM, while the BAY-293 is less active (IC50=2,340 nM)..
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DC23438 BAY 60-6583
BAY 60-6583 (BAY606583) is a potent, selective adenosine A2B receptor agonist with EC50 of 2.83 nM (murine A2BR).
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DC20748 BAY 60-2770
BAY 60-2770 is an NO-independent activator of sGC (soluble guanylyl cyclase) with EC50 of 5.4 nM.
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DC20747 BAY 41-8543
BAY 41-8543 is an NO-independent sGC (soluble guanylyl cyclase) stimulator, inhibits collagen-mediated aggregation in washed human platelets (IC50=90 nM).
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DC10291 Bay 41-4109 less active enantiomer
Bay 41-4109 less active enantiomer shows less activity than Bay 41-4109. BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM.
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DC23386 BAY 1238097
BAY 1238097 is a novel BET bromodomain inhibitor with IC50 of 50 nM, inhibits the interaction between BRD4, BRD3 or BRD2 and H4 with IC50 values of 63 nM, 609 nM and 2430 nM in the NanoBRET assay.
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DC20750 BAY 1143269
BAY 1143269 is a potent, selective, orally bioavailable inhibitor of MNK1 with enzyme IC50 of 40 nM at 2 mM ATP.
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DC23719 BAY 1024767
BAY 1024767 (BAY1024767) is a higly potent antagonist of androgen receptor (AR) wild-type (IC50=46 nM) and mutant forms located in the AR ligand-binding domain (LBD).
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DC9562 Balsalazide
Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.
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DCAPI1046 Balofloxacin
Balofloxacin
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DC20740 BAL30072
BAL30072 is a monocyclic beta-lactam antibiotic that shows potent activity against MDR Pseudomonas aeruginosa and Acinetobacter sp. Isolates with MIC90 of 8 and 4 ug/ml.
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DCAPI1066 Bacitracin zinc
Bacitracin zinc
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DC22011 BAA473
BAA473 (BAA-473) is a bile acid analogue that functions as the first small molecule activator of the Pyrin inflammasome, induces secretion of IL18 in LPS-primed PBMCs.
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DC22010 B591
B591 (B-591) is a potent, specific pan-PI3K inhibitor with IC50 of 1.3/0.36/1.1/1.58 uM for PI3Kα/β/γ/δ, respectively.
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DC12114 B I09
B I09 is an IRE-1 RNase inhibitor, with an IC50 of 1230 nM.
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DC23756 Aβ polymerization stimulator O4
Aβ polymerization stimulator O4 is an orcein-related small molecule can drive polymerization of amyloid-β (Aβ).
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