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Cat. No. Product Name Field of Application Chemical Structure
DC20130 meso-Erythritol Featured
meso-Erythritol is a sugar alcohol that occurs naturally in a variety of foods (e.g., pear, watermelon), is 60-80% as sweet as sucrose, and is an approved low-calorie sweetener food additive.
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DC20131 Methyl 3,4-dihydroxybenzoate Featured
Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester;Methyl protocatechuate) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect.
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DC24075 Midodrine Featured
Midodrine is a selective α1-adrenoceptor agonist that acts as a vasopressor/antihypotensive agent for the treatment of dysautonomia and orthostatic hypotension.
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DC24076 Midodrine hydrochloride Featured
Midodrine is a selective α1-adrenoceptor agonist that acts as a vasopressor/antihypotensive agent for the treatment of dysautonomia and orthostatic hypotension.
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DC24053 NVP-BGJ398 phosphate Featured
NVP-BGJ398 phosphate (Infigratinib phosphate, BGJ398 phosphate) is a potent, selective pan-FGFR inhibitor with IC50 of 0.9/1.0/1.4/60 nM for FGFR1/2/3/4, also shows high potenct against mutant FGFR3-K650E with IC50 of 4.9 nM.
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DC24071 PF-04217903 methanesulfonate Featured
PF-04217903 is a potent, selective, ATP-competitive c-Met kinase inhibitor with Ki of 4.8 nM, inhibits HGF-stimulated tyrosine phosphorylation of wild type c-Met with IC50 of 7.3 nM in cell-based assays.
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DC20154 Pyridoxine hydrochloride Featured
Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
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DC24047 Quizartinib hydrochloride Featured
Quizartinib (AC220) is a potent, selective, second-generation FLT3 inhibitor with Kd of 1.6 nM, inhibits Wt FLT3 and FLT3-ITD autophosphorylation in MV4-11cell with IC50 of 4.2 and 1.1 nM, respectively.
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DC20146 Sinapinic acid (Sinapic acid) Featured
Sinapinic acid (Sinapic acid) is a phenolic compound isolated from Hydnophytum formicarum Jack. Rhizome, acts as an inhibitor of HDAC, with an IC50 of 2.27 mM, and also inhibits ACE-I activity. Sinapinic acid posssess potent anti-tumor activity, induces a
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DC20104 Skatole Featured
Skatole is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.
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DC23923 D-Glutamic acid Featured
The one form of glutamic acid found in nature, is the most potent natural inhibitor of glutathione synthesis.
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DC24002 Adrafinil Featured
The prodrug of modafinil that is a mild central nervous system stimulant drug used to relieve excessive sleepiness and inattention..
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DC24070 ZM39923 Featured
ZM39923 is a potent, selective JAK3 inhibitor with pIC50 of 7.1, also potently inhibits human tissue transglutaminase (TGM2) with IC50 of 10 nM.
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DC20142 γ-Aminobutyric acid (4-Aminobutyric acid) Featured
γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors).
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DC24059 PI-103 hydrochloride Featured
A potent, dual class I PI3K/mTOR inhibitor with IC50 of 2/3/3/15/ for p110α/β/δ/γ, respectively.
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DC22488 Corticotropin-releasing factor (human) Featured
Corticotropin-releasing hormone (CRH) is a peptide hormone involved in the stress response..
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DC21684 Ryuvidine Featured
Ryuvidine is a potent, selective CDK4 inhibitor with IC50 of 6.0 uM, displays >30-fold selectivity over CDK2 (IC50>100 uM).
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DC34066 Propidium Iodide Featured
Propidium Iodide is a fluorescent intercalating agent that can be used to stain cells. Propidium Iodide is used as a DNA stain in flow cytometry to evaluate cell viability or DNA content in cell cycle analysis, and in microscopy to visualise the nucleus and other DNA-containing organelles. Propidium Iodide cannot cross the membrane of live cells, making it useful to differentiate necrotic, apoptotic and healthy cells.
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DC29181 Neryl acetate Featured
Neryl acetate is a chemical compound isolated from citrus oils.
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DC29159 Nonadecanoic acid Featured
Nonadecanoic acid is a 19-carbon long saturated fatty acid. Nonadecanoic acid is the major constituent of the substance secreted by Rhinotermes marginalis to defence.
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DC28128 (S)-Trolox Featured
(S)-Trolox is a analogue of vitamin E, in which the phytyl chain is replaced with a carboxyl group. (S)-Trolox is frequently used as a model compound for studies of structural features, as well as a standard for evaluation of antioxidant activity. (S)-Trolox has potent and specific neuroprotective and antioxidant effects.
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DC24048 NVP-BKM120 hydrochloride Featured
A potent, selective, orally bioavailable inhibitor of class I PI3K isoforms with IC50 of 52 nM/166 nM/116 nM/262 nM for p110α/β/δ/γ, respectively.
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DC34751 DTSSP Crosslinker Featured
DTSSP Crosslinker, or 3,3′-Dithiobis[sulfosuccinimidylpropionate], is a homobifunctional protein crosslinker that is cell membrane impermeable. DTSSP crosslinker can be used to crosslink extracellular and membrane proteins.
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DC24068 AVL-292 besylate Featured
AVL-292 besylate (Spebrutinib, CC-292) is a highly selective, covalent Btk inhibitor with IC50 of <1 nM.
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DC24090 KX2-391 dihydrochloride Featured
A highly selective, non-ATP competitive substrate-pocket-directed Src/pretubulin inhibitor.
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DC29169 Vanillin acetate Featured
Vanillin acetate is easily synthesized from vanillin by treatment with acetic anhydride.
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DC29067 Spermidine trihydrochloride Featured
Spermidine trihydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine trihydrochloride significantly decreases the H2O2 and O2.- contents.
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DC31650 Dicumarol Featured
Dicoumarol (INN) or dicumarol (USAN) is a naturally occurring anticoagulant that functions as a functional vitamin K depleter (similar to warfarin, a drug that dicoumarol inspired). It is also used in biochemical experiments as an inhibitor of reductases. Like all 4-hydroxycoumarin drugs it is a competitive inhibitor of vitamin K epoxide reductase, an enzyme that recycles vitamin K, thus causing depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes. These compounds are not antagonists of Vitamin K directly—as they are in pharmaceutical uses—but rather promote depletion of vitamin K in bodily tissues allowing vitamin K's mechanism of action as a potent medication for dicoumarol toxicity. The mechanism of action of Vitamin K along with the toxicity of dicoumarol are measured with the prothrombin time (PT) blood test. (Source: https://en.wikipedia.org/wiki/Dicoumarol).
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DC45134 2′-O-Methyluridine Featured
2'-O-methyluridine is found in rRNA, snRNA, snoRNA and tRNA of Archaea, Bacteria, and Eukaryota.
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DC33388 Amphotericin B Featured
Amphotericin B binds ergosterol and induces membrane pore formations, increasing ROS and suppressing fungal growth. It also increases expression of IL-1-beta, TNF-alpha, BDNF and GDNF and protects against prion-induced neurodegeneration.
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