Partial agonist in CXCR3-mediated chemotaxis, bound to CXCR3 in an allosteric fashion with the same efficacy as CXCL11

Potent inhibitor of lipid droplet formation

Highly specific allosteric activator for the tumor-specific isoform of human pyruvate kinase (M2 isoform)

Selective modulator of NMDA receptors, potentiates responses at GluN1/GluN2D

Inhibitor of the uPAR·uPA protein-protein interaction, blocking cancer cell invasion

A selective inhibitor of c-Met kinase

Selective and potent antagonist of the transient receptor potential melastatin-8 (TRPM8) channel

5-HT1A/1B serotonin receptor antagonist; β3-adrenoceptor antagonist

Highly selective D2 dopamine receptor antagonist

Potent P2X7 antagonist blocking BzATP-evoked calcium influx

Potent in vitro and in vivo inhibitor of fatty acid amide hydrolase (FAAH)

Novel Inhibitor of Bacterial Cytokinesis, inhibiting FtsZ

Calcium entry blocker, also being used as the precursor for radiolabelling emopamil

Novel reversible inhibitor of autophagic flux, preventing Stx17 loading onto autophagosomes and blocking autophagosome-lysosome fusion without any effect on lysosomal properties or on endocytosis mediated degradation of EGF receptor

Glucocorticosteroid; Antipsoriatic agent