GSK-364735 sodium (S/GSK-364735 sodium) is the sodium salt form of GSK-364735 that inhibits 5-lipoxygenase with an IC50 value of 26 μM. 15(S)-HEDE is promising for research of inflammatory disease.

GSK-364735 potassium (S/GSK-364735 potassium) is the potassium salt form of GSK-364735, a local anesthetic that inhibits dopamine reuptake through the dopamine transporter.

Gardiquimod (hydrochloride) is an imidazoline TLR7/8 agonist. Gardiquimod (hydrochloride) inhibits HIV-1 infection of macrophages and activates peripheral blood mononuclear cells (PBMCs). Gardiquimod (hydrochloride) specifically activates TLR7 at concentrations below 10 μM.

CGP 57813 is a peptidomimetic inhibitor of HIV protease that can be encapsulated by nanoparticles composed of poly(D,L-lactic acid) (PLA) and pH-sensitive methacrylic acid copolymers and delivered into the body.

BRN3OMe is a potent HIV-1 reverse transcriptase inhibitor. BRN3OMe has the potential for the research of antiviral agent.

Netanasvir, a NS5A inhibitor, possesses antiviral activity. Netanasvir can be used in the study for HCV study.

ML283 is a HCV NS3 helicase inhibitor (IC50: 2.6 μM). ML283 also inhibits DenV ATPase (IC50: 4.0 μM).

Encofosbuvir is the inhibitor for HCV NS5B polymerase that inhibits GT1b, GT2a and GT3a with EC50 of 102.4, 82.51 and 46.91 nM. Encofosbuvir inhibits HCV replication and can be used for reseearchs of hepatitis C in mammals.

3′-Deoxy CTP trisodium is the sodium salt form of 3′-Deoxy CTP. Prednisolone is a potent, orally active corticosteroid and a glucocorticoid.

3′-Deoxy CTP is a nucleotide analogue and a mandatory chain terminator. 3′-Deoxy CTP can cause chain termination by lacking the 3′-hydroxyl group, inhibiting the RNA synthesis activity of HCV nonstructural protein (NS5B) polymerase and blocking viral replication. 3′-Deoxy CTP can be used to study the chain termination mechanism of HCV polymerase and the development of antiviral drugs.

Rapavir (JH-B10) is a selective and potent sodium taurocholate cotransporting polypeptide (NTCP) inhibitor with an IC50 value of 1.8 nM for the uptake of taurocholic acid-d4 (TCA-d4). Rapavir exerts antiviral activity by directly binding to NTCP and blocking the entry of the virus into cells during the HBV infection phase. Rapavir is promising for research of HBV infections.

Morphothiadin (GLS4) mesylate is a potent inhibitor of wild-type and Adefovir-resistant HBV replication with an IC50 value of 12 nM.

KR019 is a potent HBV capsid assembly modulator, exhibits potent antiviral activity in HBV-replicating cells. KR019 binds to the hydrophobic pocket at the core protein dimer-dimer interface, misdirecting capsid assembly into genome-free capsids and thereby inhibiting viral replication.

Destruxin B2 (compound 5) is a natural depsipeptide that can be inhibits hepatitis B surface antigen (HBsAg) secretion in Hep3B cells with an IC50 1.30 μM.

BA-AZT1 is the inhibitor for HBV polymerase and sodium taurocholate cotransporting polypeptide (NTCP). BA-AZT1 inhibits the secretion of viral capsid protein HBsAg and HBeAg with IC50 of 0.65 µM and 13.42 µM, inhibits the HBV DNA replication with an IC50 of 0.70 µM.

ALG-000184, a prodrug of the potent Hhepatitis B virus (HBV) capsid assembly modulator ALG-001075, has the potential for the research of HBV infection research.

AIC263282 is a potent Hepatitis B Virus (HBV) capsid assembly modulator with an EC50 of 3.8 nM. AIC263282 shows an IC50 of 61 nM for hERG. AIC263282 exhibits activity against viral replication and hepatitis B surface antigen (HBsAG) on primary human hepatocytes.

Racemomycin C has broad spectrum antibacterial activity and antifungal effect, and it can inhibit PR-8 of influenza virus in tissue culture.

Oudemansin A is an antibiotic. Oudemansin A acts on fungi to inhibit protein, RNA and DNA synthesis.

Aurachin C is an isoprenoid quinoline alkaloid with antiplasmodial, antifungal and antibacterial effects. Aurachin C is a selective terminal oxidases inhibitor.

Aklavin is an antibiotic that shows activity against various bacteriophages, Gram-positive bacteria, and some fungi and viruses.

MDL-860 is a broad-spectrum antipicornavirus compound that has low cytotoxicity toward human cells. MDL-860 can be used for the research of virus infection.

HR-568 exhibits broad-spectrum anti-enterovirus activity. HR-568 inhibits enterovirus species EV-A71, E30 and CVA24 in cell MRC-5 with EC50 of 1.53 μM, 0.4 μM and 1.22 μM. HR-568 targets hydrophobic canyon pocket on the enterovirus capsid protein, and inhibits the virus replication.

DC07090 is a potent, reversible and competitive non-peptidyl human enterovirus 71 3C protease inhibitor with an IC50 and a Ki value for 21.72 μM and 23.29 μM. DC07090 could also inhibit coxsackievirus A16 (CVA16) replication with an EC50 value of 27.76 μM.

ε-Rhodomycinone is a bacterial metabolite found in S. griseoruber. It is a precursor to Rhodomycin D, which is an intermediate in the bioconversion of ε-rhodomycinone to Daunorubicin and Doxorubicin.

VPC162134 is an antibacterial agent, that inhibits H. pylori, C. jejuni, MRSA and S. epidermidis with MIC of 2.9, 17.5, 93.3 and 93.3 μM. VPC162134 is an inhibitor for pyruvate ferredoxin oxidoreductase (PFOR).

Vancomycin prodrug (compound 13c) is a Vancomycin prodrug. Vancomycin prodrug shows antibacterial effect with MICs of 0.78 μM, 0.78 μM, 1.56 μM for S. aureus 330041, MRSA USA 300 and MRSA 3390, respectively. Vancomycin prodrug has the ability to quickly bind to Cys-34 residue of plasma. Vancomycin prodrug exhibits a good therapeutic effect on MRSA USA300 infected mice similar to Vancomycin. Vancomycin prodrug, an albumin-binding acid-sensitive prodrug, effectively reduces Vancomycin’s nephrotoxicity while maintaining its efficacy for Gram-positive bacterial infections.

Thiocillin is a thiopeptide class of RiPPs and anti-bacterial agent. Thiocillin targets the bacterial 50S ribosome. Thiocillin exhibits potent antibacterial activity against a number of agent resistant pathogens.

Tenonitrozole exhibits antibacterial activity through inhibition of pyruvate-ferredoxin oxidoreductase (PFOR). Tenonitrozole inhibits H. pylori and C. jejuni with MICs of 0.7 μM and 5.9 μM.

Tembetarine chloride is a alkaloid that can be isolated from Tinospora cordifolia that exhibits antibacterial activity. Tembetarine chloride exhibits weak cytotoxicity against mouse fibroblasts (L929) and human embryonic kidney cells (HEK293) with IC50 of 1245.33 μg/mL and 1642.81 μg/mL, respectively.