Boc-NH-PEG7-acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Fmoc-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

t-Boc-Aminooxy-PEG4-t-butyl ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Bromo-PEG7-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Cbz-PEG5-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Triethylene glycol monododecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Br-PEG6-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

BocNH-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Bromo-C4-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Bromo-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Bromo-PEG5-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

t-Boc-Aminooxy-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

t-Boc-N-amido-PEG2-C6-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Amino-PEG6-acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Iodo-PEG7-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Cbz-PEG2-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Benzyl-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Mal-amido-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

2-(2-(6-chlorohexyloxy)ethoxy)ethanamine (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

L-Azidohomoalanine-1,2,3,4-13C4 hydrochloride is the 13C- and 15N-labeled L-Azidohomoalanine hydrochloride. L-Azidohomoalanine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

m-PEGn-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

tert-Butyl 11-aminoundecanoate (compound 6b) is a PROTAC linker that refers to the PEG composition. tert-Butyl 11-aminoundecanoate is applicable to the synthesis of a series of PROTACs.

Di(N-succinimidyl) adipate (DSAP) is an alkyl chain-based PROTAC linker that is applicable to the synthesis of PROTACs.

DT2216 is a selective B-cell lymphoma extra large (BCL-XL) proteolysis-targeting chimera (PROTAC). DT2216 targets BCL-XL to the Von Hippel-Lindau (VHL) E3 ligase for degradation. DT2216 inhibits various BCL-XL-dependent leukemia and cancer cells but considerably less toxic to platelets.

Boc-NH-PEG11-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a VHL ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectively.

CNX-500 is a probe consisting of a covalent Btk inhibitor (CC-292) chemically linked to biotin. CNX-500 retains inhibitory activity against Btk (IC50 of 0.5 nM) and the ability to form a covalent bond with Btk. CNX-500 has low inhibitory effects on kinase epidermal growth factor receptor, and upstream Src-family kinases including Syk and Lyn.

RapaLink-1 is a third-generation mTOR inhibitor that overcomes resistance to existing first- and second-generation inhibitors; blocks mTOR signaling of the F2108L mTOR and M2327I mTOR drug resistant mutants; RapaLink-1 is more potent mTOR inhibitor than rapamycin.

ATP-PEG8-Biotin is a PEG-based linker that incorporates ATP. ATP is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.

Biotin-PEG7-C2-NH-Vidarabine-S-CH3 is a PEG-based linker that incorporates adenosine analog Vidarabine. Vidarabine is an antiviral agent which is active against herpes simplex and varicella zoster viruses.