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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC79428 | PROTAC BRD4 ligand-4 |
PROTAC BRD4 ligand-4 is a BRD4 ligand, which can be used to synthesize PROTAC BRD4 Degrader-37.
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| DC79425 | FAK ligand-5 |
FAK ligand-5 (BI-4464) is a FAK inhibitor, with an IC50 of 25 nM. FAK ligand-5 can serve as a ligand for target protein for PROTAC, used in the development and design of degraders for PROTAC FAK. FAK ligand-5 can be used in the synthesis of PROTAC FAK degrader 4. FAK ligand-5 can be used in cancer research.
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| DC79403 | BCL-xL ligand 2 |
BCL-xL ligand 2 is a ligand for BCL-xL. BCL-xL ligand 2 can be conjugated with E3 ligase Ligand and linker to synthesize Bcl-xL PROTAC degrader PZ671.
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| DC79397 | HDAC6 ligand-5 |
HDAC6 ligand-5 is a binding ligand of HDAC6 and can be used to synthesize PROTACs such as PROTAC HDAC6 degrader 5.
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| DC79369 | sEH-H ligand 2 |
sEH-H ligand 2 is an sEH inhibitor and a ligand for the target protein for PROTAC (sEH). sEH-H ligand 2 can be used to synthesize PROTAC sEH-degrader-4.
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| DC79354 | sEH-H ligand 1 |
sEH-H ligand 1 is a PROTAC target protein ligand that can be used to synthesize PROTAC sEH degrader-2.
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| DC79339 | MNK1 ligand 1 |
MNK1 ligand 1 (Compound 5) is a MNK1 ligand. MNK1 ligand 1 can be used for synthesis of PROTAC MNK1 degrader-1.
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| DC79336 | ASK1 ligand 1 |
ASK1 ligand 1 is a binding ligand for ASK1 and can be used to synthesize PROTACs such as dASK1-VHL.
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| DC79305 | PRMT5 ligand 2 |
PRMT5 ligand 2 (Compound 38) is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). PRMT5 ligand 2 can be used for synthesis MS115.
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| DC79273 | NASA-linker-VH032-PEG3 ligand |
NASA-linker-VH032-PEG3 ligand is a ligand that can be used to synthesize PROTACs.
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| DC79228 | HPK1 ligand 4 |
HPK1 ligand 4 is a PROTAC target protein ligand that can be used for synthesis of PROTACs, such as PROTAC HPK1 Degrader-5. PROTAC HPK1 Degrader-5 is a potent and orally active HPK1 PROTAC degrader with anti-tumor activity.
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| DC79143 | TBK1 ligand 2 |
TBK1 ligand 2 (Compound 1b) is a TBK1 inhibitor. TBK1 ligand 2 can be used for synthesis of PROTAC TBK1 degrader-2.
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| DC79133 | Rimonabant carboxylic acid |
Rimonabant carboxylic acid is a Ligand for Target Protein for PROTAC. Rimonabant carboxylic acid can be used to synthesize PROTAC CB1R Degrader-1.
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| DC79114 | STAT6 ligand-1 |
STAT6 ligand-1 is a ligand for STAT6. STAT6 ligand-1 can be used for synthesizing PROTACs such as STAT6 degrader-2.
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| DC79033 | BRAF ligand-1 |
BRAF ligand-1 is the ligand of BRAF. BRAF ligand-1 can be used to synthesize CST905.
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| DC79031 | HBeAg ligand 1 |
HBeAg ligand 1 (Compound S2) is a HBeAg inhibitor. HBeAg ligand 1 can be used for synthesis of PROTAC HBeAg degrader-1.
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| DC79019 | ERK5 ligand-1 |
ERK5 ligand-1 is a is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC). ERK5 ligand-1 can be used to design PROTAC, such as PROTAC ERK5 degrader-1.
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| DC79003 | 3-Fluoro-desmethyl-cabozantinib |
3-Fluoro-desmethyl-cabozantinib is an BCL6 ligand that can be used in the synthesis of PROTACs, such as SJF-8240.
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| DC78987 | BRD4 ligand 8 |
BRD4 ligand 8 (Compound J558) is a BRD4 inhibitor. BRD4 ligand 8 can be used for synthesis of PROTAC BRD4 Degrader-33.
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| DC78936 | TERT ligand-1 |
TERT ligand-1 is a PROTAC target protein ligand that can be used to synthesize the PROTAC NU-PRO-1. NU-PRO-1 induces TERT degradation in cancer cells.
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| DC78836 | AY-2 |
AY-2 is a binding ligand for FTH1 and can be used to synthesize PROTACs such as AY-4.
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| DC78787 | PXR Ligand 3 |
PXR Ligand 3 is a PXP ligand. PXR Ligand 3 can be used to synthesize PROTAC MI1013.
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| DC78786 | MMH-165-26 |
MMH-165-26 is a ligand for RelA/p65. MMH-165-26 reduces the expression of RelA/p65 and has significant cytotoxicity in MEC-1 (LC50 = 0.37 μM) cells. MMH-165-26 can be used for synthesizing PROTACs such as JP-163-16.
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| DC78775 | PBRM1/SMARCA2,4-ligand-1 |
PBRM1/SMARCA2,4-ligand-1 (Compound 4) is a Ligand for Target Protein for PROTAC that binds to PBRM1, SMARCA2, and SMARCA4. PBRM1/SMARCA2,4-ligand-1 is a potent SMARCA4 bromodomain inhibitor. PBRM1/SMARCA2,4-ligand-1 can be used to synthesize PROTAC AU-24118.
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| DC78756 | BTK ligand 16 |
BTK ligand 16 is a BTK ligand that can be used for synthesis of TQ-3959.
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| DC78735 | FLT3/CHK1 ligand-1 |
FLT3/CHK1 ligand-1 is a PROTAC target protein ligand that can be used for synthesis of PROTACs, such as PROTAC FLT3/CHK1 Degrader-1. PROTAC FLT3/CHK1 Degrader-1 is a potent FLT3/CHK1 PROTAC degrader with anti-tumor activity.
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| DC78733 | IAP ligand 5 |
IAP ligand 5 is a IAP ligand. IAP ligand 5 can be used to synthesize PROTAC ERα Degrader-2.
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| DC78721 | Androgen receptor ligand 2 |
Androgen receptor ligand 2 is a PROTAC target protein ligand that can be used to synthesize the PROTAC Androgen receptor degrader-1.
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| DC78699 | DH03 |
DH03 (6-Amino-4-[(3-chloro-4-fluorophenyl)amino]-7-ethoxyquinoline-3-carbonitrile) is a SARS-CoV-2 MPro ligand. DH03 can be used as a Ligand for Target Protein for PROTAC synthesis, such as PROTAC SARS-CoV-2 Degrader-1.
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| DC78671 | EGFR ligand-14 |
EGFR ligand-14 is an EGFR ligand. EGFR ligand-14 can be used for the synthesis of SJF-1521.
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