NU-PRO-1 is a covalent Telomerase reverse transcriptase (TERT) PROTAC degrader. NU-PRO-1 dose not induce DNA damage on its own but acts to further delay DNA repair after irradiation.

E3 ligase Ligand 58 is an E3 ligase ligand. E3 ligase Ligand 58 can be used for synthesis of PROTAC AH078.

E3 ligase Ligand 76 is a E3 ligase ligand that can be used in the recruitment of VHL protein. E3 ligase Ligand 76 can be connected to the KRAS ligand by a linker to synthesis of PROTAC KRAS(on) degrader ACBI-4.

AY-4 (Compound AY-4) is an efficient PROTAC degrader targeting FTH1 (Kd = 3.17 nM). AY-4 effectively upregulates the levels of ferrous (Fe2+) and ferric (Fe3+) ions in cells. AY-4 is a potential anticancer candidate compound that regulates iron homeostasis through ferritin degradation and enhances the efficacy of existing drugs. AY-4 can effectively reduce the level of FTH1 in breast cancer cells.

AY-2 is a binding ligand for FTH1 and can be used to synthesize PROTACs such as AY-4.

E3 Ligase Ligand-linker Conjugate 196 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 196 can be used in the synthesis of PROTAC BRD4 Degrader-38.

Acepromazine-1-piperazinepropanamine dihydrochloride (compound 10) is a synthesized E3 ligase ligand-linker conjugate (E3 Ligase Ligand-Linker Conjugate) that incorporates a TRIM21 ligand and a linker. Acepromazine-1-piperazinepropanamine dihydrochloride can be connected to the target protein ligand to form a PROTAC molecule, TrimTAC1.

E3 Ligase Ligand-linker Conjugate 186 is a CRBN E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 186 can be used to synthesize PROTAC SJ10542.

Pomalidomide-5-C7-NH2 is an E3 ligase ligand-linker conjugate that incorporates the 5-Aminothalidomide based CRBN ligand and linker. Pomalidomide-5-C7-NH2 can be used for synthesis of PROTAC BT-O2C

Thalidomide-C-amide-C5-amine is an E3 ligase ligand. Thalidomide-C-amide-C5-amine can be used for synthesis of PROTAC BET Degrader-10.

(1-(7-Bromoheptyl)piperidin-4-yl)methanamine is a PROTAC linker. (1-(7-Bromoheptyl)piperidin-4-yl)methanamine can be used in synthesis ZS3-046.

E3 Ligase Ligand-linker Conjugate 210 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 210 can be used to synthesize PROTAC CB1R Degrader-1.

2-[4-(Aminomethyl)triazol-1-yl]ethanamine is a PROTAC Linker. 2-[4-(Aminomethyl)triazol-1-yl]ethanamine can be used to synthesize PROTAC CB1R Degrader-1.

BTR2000-Gly-Gly-Gly TFA is a E3 ligase ligand-linker conjugate (KLHL20) that can be used for the synthesis of PROTAC BTR2004.

(R,S,S)-VH032-Me-glycine is an E3 ligase ligand-linker conjugate. (R,S,S)-VH032-Me-glycine can be used to synthesize XF067-68.

PXR Ligand 3 is a PXP ligand. PXR Ligand 3 can be used to synthesize PROTAC MI1013.

MMH-165-26 is a ligand for RelA/p65. MMH-165-26 reduces the expression of RelA/p65 and has significant cytotoxicity in MEC-1 (LC50 = 0.37 μM) cells. MMH-165-26 can be used for synthesizing PROTACs such as JP-163-16.

RNase L ligand 3 is a RNase L ligand. RNase L ligand 3 can be used for synthesis of F3-PEG8-RiboTAC.

PBRM1/SMARCA2,4-ligand-1 (Compound 4) is a Ligand for Target Protein for PROTAC that binds to PBRM1, SMARCA2, and SMARCA4. PBRM1/SMARCA2,4-ligand-1 is a potent SMARCA4 bromodomain inhibitor. PBRM1/SMARCA2,4-ligand-1 can be used to synthesize PROTAC AU-24118.

TQ-3959 is an orally active BTK PROTAC degrader, with a DC50 of 14.6 nM. TQ-3959 exerts antiproliferative activity against both wild-type BTK and C481S mutant BTK cell lines. TQ-3959 exhibits tumor growth inhibition in female NOD-SCID mice bearing TMD-8 xenografts. TQ-3959 can be used in the research on B-cell malignancies such as lymphoma.

BTK ligand 16 is a BTK ligand that can be used for synthesis of TQ-3959.

JPS004 is a HDAC1-3 PROTAC degrader. JPS004 can induce degradation of HDAC1-3 and induce histone acetylation. JPS004 can induce cancer cells apoptosis. JPS004 can be used for the research of cancer.

OICR-41103N is the negative control form of OICR-41103. OICR-41103 is an effective, selective, cell-active DCAF1 small molecule chemical probe (Ki<2 nM) that targets the DCAF1 WDR domain and replaces the viral Vpr protein.

OICR-41103 is an effective, selective, cell-active DCAF1 small molecule chemical probe that targets the DCAF1 WDR domain and replaces the viral Vpr protein. The binding Ki value of OICR-41103 and DCAF1 is less than 2 nM.

(S,S,S)-AHPC-Me is an E3 ligase ligand. (S,S,S)-AHPC-Me can be used for synthesis of PROTAC (4S)-PROTAC SOS1 degrader-1 diTFA.

FLT3/CHK1 ligand-1 is a PROTAC target protein ligand that can be used for synthesis of PROTACs, such as PROTAC FLT3/CHK1 Degrader-1. PROTAC FLT3/CHK1 Degrader-1 is a potent FLT3/CHK1 PROTAC degrader with anti-tumor activity.

IAP ligand 5 is a IAP ligand. IAP ligand 5 can be used to synthesize PROTAC ERα Degrader-2.

E3 ligase Ligand 60 is a ligand for E3 ligase, used for the synthesis of JV8.

(R,S,S)-VH032-Me TFA is an E3 ligase Ligand and can be used for synthesis of dTAGV-1 hydrochloride.

Androgen receptor ligand 2 is a PROTAC target protein ligand that can be used to synthesize the PROTAC Androgen receptor degrader-1.