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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC79033 | BRAF ligand-1 |
BRAF ligand-1 is the ligand of BRAF. BRAF ligand-1 can be used to synthesize CST905.
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| DC79031 | HBeAg ligand 1 |
HBeAg ligand 1 (Compound S2) is a HBeAg inhibitor. HBeAg ligand 1 can be used for synthesis of PROTAC HBeAg degrader-1.
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| DC79019 | ERK5 ligand-1 |
ERK5 ligand-1 is a is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC). ERK5 ligand-1 can be used to design PROTAC, such as PROTAC ERK5 degrader-1.
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| DC79003 | 3-Fluoro-desmethyl-cabozantinib |
3-Fluoro-desmethyl-cabozantinib is an BCL6 ligand that can be used in the synthesis of PROTACs, such as SJF-8240.
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| DC78991 | H-Cit-Lys(ma-Lys(PEG16))-Tyr-OH |
H-Cit-Lys(ma-Lys(PEG16))-Tyr-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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| DC78987 | BRD4 ligand 8 |
BRD4 ligand 8 (Compound J558) is a BRD4 inhibitor. BRD4 ligand 8 can be used for synthesis of PROTAC BRD4 Degrader-33.
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| DC78968 | Thalidomide-piperazine-CO-C-azacyclohexane-C1-piperazine |
Thalidomide-piperazine-CO-C-azacyclohexane-C1-piperazine is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-piperazine-CO-C-azacyclohexane-C1-piperazine can be used for synthesizing PROTAC CDK4/6/9 degrader 1.
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| DC78966 | CRBN ligand-Linker Conjugate 1 |
CRBN ligand-Linker Conjugate 1 is a CRBN ligand-linker conjugate that can be used for synthesis of TQ-3959.
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| DC78958 | DDD2 |
DDD2 is a selective and potent VHL-mediated PROTAC NUDT5 degrader. DDD2 induces robust NUDT5 degradation. DDD2 can be used in cancer research, such as lymphocytic leukemia and osteosarcoma.
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| DC78955 | CST905 |
CST905 is a potent PROTAC degrader of BRAF-V600E with a DC50 of 18 nM. CST905 is suitable for cancer research.
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| DC78954 | E3 Ligase Ligand-linker Conjugate 178 |
E3 Ligase Ligand-linker Conjugate 178 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 178 can be used to synthesize MS2133.
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| DC78953 | E3 Ligase Ligand-linker Conjugate 211 |
E3 Ligase Ligand-linker Conjugate 211 is an E3 ligase ligand-linker conjugate containing a cereblon (CRBN) ligand for E3 ubiquitin ligase and a linker. E3 Ligase Ligand-linker Conjugate 211 can be used to synthesize PROTAC FAK degrader 4.
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| DC78936 | TERT ligand-1 |
TERT ligand-1 is a PROTAC target protein ligand that can be used to synthesize the PROTAC NU-PRO-1. NU-PRO-1 induces TERT degradation in cancer cells.
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| DC78935 | NU-PRO-1 |
NU-PRO-1 is a covalent Telomerase reverse transcriptase (TERT) PROTAC degrader. NU-PRO-1 dose not induce DNA damage on its own but acts to further delay DNA repair after irradiation.
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| DC78933 | E3 ligase Ligand 58 |
E3 ligase Ligand 58 is an E3 ligase ligand. E3 ligase Ligand 58 can be used for synthesis of PROTAC AH078.
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| DC78911 | E3 ligase Ligand 76 |
E3 ligase Ligand 76 is a E3 ligase ligand that can be used in the recruitment of VHL protein. E3 ligase Ligand 76 can be connected to the KRAS ligand by a linker to synthesis of PROTAC KRAS(on) degrader ACBI-4.
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| DC78837 | AY-4 |
AY-4 (Compound AY-4) is an efficient PROTAC degrader targeting FTH1 (Kd = 3.17 nM). AY-4 effectively upregulates the levels of ferrous (Fe2+) and ferric (Fe3+) ions in cells. AY-4 is a potential anticancer candidate compound that regulates iron homeostasis through ferritin degradation and enhances the efficacy of existing drugs. AY-4 can effectively reduce the level of FTH1 in breast cancer cells.
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| DC78836 | AY-2 |
AY-2 is a binding ligand for FTH1 and can be used to synthesize PROTACs such as AY-4.
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| DC78834 | E3 Ligase Ligand-linker Conjugate 196 |
E3 Ligase Ligand-linker Conjugate 196 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 196 can be used in the synthesis of PROTAC BRD4 Degrader-38.
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| DC78833 | Acepromazine-1-piperazinepropanamine dihydrochloride |
Acepromazine-1-piperazinepropanamine dihydrochloride (compound 10) is a synthesized E3 ligase ligand-linker conjugate (E3 Ligase Ligand-Linker Conjugate) that incorporates a TRIM21 ligand and a linker. Acepromazine-1-piperazinepropanamine dihydrochloride can be connected to the target protein ligand to form a PROTAC molecule, TrimTAC1.
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| DC78832 | E3 Ligase Ligand-linker Conjugate 186 |
E3 Ligase Ligand-linker Conjugate 186 is a CRBN E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 186 can be used to synthesize PROTAC SJ10542.
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| DC78829 | Pomalidomide-5-C7-NH2 |
Pomalidomide-5-C7-NH2 is an E3 ligase ligand-linker conjugate that incorporates the 5-Aminothalidomide based CRBN ligand and linker. Pomalidomide-5-C7-NH2 can be used for synthesis of PROTAC BT-O2C
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| DC78828 | Thalidomide-C-amide-C5-amine |
Thalidomide-C-amide-C5-amine is an E3 ligase ligand. Thalidomide-C-amide-C5-amine can be used for synthesis of PROTAC BET Degrader-10.
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| DC78821 | (1-(7-Bromoheptyl)piperidin-4-yl)methanamine |
(1-(7-Bromoheptyl)piperidin-4-yl)methanamine is a PROTAC linker. (1-(7-Bromoheptyl)piperidin-4-yl)methanamine can be used in synthesis ZS3-046.
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| DC78820 | E3 Ligase Ligand-linker Conjugate 210 |
E3 Ligase Ligand-linker Conjugate 210 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 210 can be used to synthesize PROTAC CB1R Degrader-1.
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| DC78819 | 2-[4-(Aminomethyl)triazol-1-yl]ethanamine |
2-[4-(Aminomethyl)triazol-1-yl]ethanamine is a PROTAC Linker. 2-[4-(Aminomethyl)triazol-1-yl]ethanamine can be used to synthesize PROTAC CB1R Degrader-1.
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| DC78808 | BTR2000-Gly-Gly-Gly TFA |
BTR2000-Gly-Gly-Gly TFA is a E3 ligase ligand-linker conjugate (KLHL20) that can be used for the synthesis of PROTAC BTR2004.
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| DC78807 | (R,S,S)-VH032-Me-glycine |
(R,S,S)-VH032-Me-glycine is an E3 ligase ligand-linker conjugate. (R,S,S)-VH032-Me-glycine can be used to synthesize XF067-68.
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| DC78787 | PXR Ligand 3 |
PXR Ligand 3 is a PXP ligand. PXR Ligand 3 can be used to synthesize PROTAC MI1013.
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| DC78786 | MMH-165-26 |
MMH-165-26 is a ligand for RelA/p65. MMH-165-26 reduces the expression of RelA/p65 and has significant cytotoxicity in MEC-1 (LC50 = 0.37 μM) cells. MMH-165-26 can be used for synthesizing PROTACs such as JP-163-16.
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