Cat. No. | Product Name | Field of Application | Chemical Structure |
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DC41140 | Amino-PEG4-C1-Boc |
Amino-PEG4-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC41058 | Biotin-PEG4-hydrazide TFA |
Biotin-PEG4-hydrazide (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC41057 | L-Azidohomoalanine hydrochloride |
L-Azidohomoalanine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC41056 | N-(Amino-PEG2)-N-bis(PEG3-azide) |
N-(Amino-PEG2)-N-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC41045 | Pomalidomide-PEG1-C2-COOH |
Pomalidomide-PEG1-C2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 1-unit PEG linker used in PROTAC technology.
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DC41044 | PROTAC KRASG12C Degrader-LC-2 |
PROTAC KRASG12C Degrader-LC-2 is a potent and first-in-class degrader of endogenous KRAS G12C with DC50 values between 0.25 and 0.76 μM. PROTAC KRASG12C Degrader-LC-2 is composed of a covalent KRAS G12C inhibitor MRTX849, a VHL ligand and a linker.
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DC40887 | Thiol-PEG-Tetrazine (MW 5kDa) |
Thiol-PEG-Tetrazine (MW 5kDa) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC40867 | Boc-A 410099.1 amide-alkylC4-amine |
Boc-A 410099.1 amide-alkylC4-amine is a functionalized IAP ligand for PROTACs that incorporates an IAP ligand and an amide-alkylC4 linker with terminal amine. Boc-A 410099.1 amide-alkylC4-amine can conjugates with target protein ligands.
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DC40866 | A 410099.1 amide-PEG2-amine-Boc |
A 410099.1 amide-PEG2-amine-Boc is a functionalized IAP ligand for PROTACs that incorporates an IAP ligand and an amide-PEG3 linker with terminal amine. A 410099.1 amide-PEG2-amine-Boc can conjugates with target protein ligands.
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DC40865 | A 410099.1 amide-PEG3-amine-Boc |
A 410099.1 amide-PEG3-amine-Boc is a functionalized IAP ligand for PROTACs that incorporates an IAP ligand and an amide-PEG3 linker with terminal amine. A 410099.1 amide-PEG3-amine-Boc can conjugates with target protein ligands.
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DC40864 | A 410099.1, amine-Boc hydrochloride |
A 410099.1, amine-Boc hydrochloride is a?functionalized IAP ligand for PROTACs. that is incorporates with an amine functional handle for ready conjugation to a linker/target protein ligand.
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DC40858 | BSJ-04-132 |
BSJ-04-132 is a potent and selective Ribociclib-based CDK4 degrader (PROTAC), with IC50s of 50.6 nM and 30 nM for CDK4/D1 and CDK6/D1, respectively. BSJ-04-132 does not induce CDK6 and IKZF1/3 degradation. BSJ-04-132 has anti-cancer activity.
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DC40844 | (S,R,S)-AHPC-C5-NH2 |
(S,R,S)-AHPC-C5-NH2 (VH032-C5-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader.
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DC40843 | (S,R,S)-AHPC-C7-amine |
(S,R,S)-AHPC-C7-amine (VH032-C7-amine) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader.
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DC40842 | Mal-amino-sulfo |
Mal-amino-sulfo is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC40840 | 6-Maleimidocaproic acid sulfo-NHS |
6-Maleimidocaproic acid sulfo-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC40834 | Aldehyde-benzyl-PEG5-alkyne |
Aldehyde-benzyl-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC40737 | Pomalidomide-C7-COOH |
Pomalidomide-C7-COOH is a synthesized E3 ligase cereblon ligand-linker conjugate. Pomalidomide-C7-COOH is an intermediate for the synthesis of PROTAC BCL-XL degraders.
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DC40723 | PROTAC BRD4 Degrader-5 |
PROTAC BRD4 Degrader-5 is a PROTAC-based BRD4 degrader. PROTAC BRD4 Degrader-5 can potent degrade BRD4 in HER2 positive and negative breast cancer cell lines.
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DC40722 | PROTAC BRD4 Degrader-5-CO-PEG3-N3 |
PROTAC BRD4 Degrader-5-CO-PEG3-N3 (Compound 2) is a PROTAC-linker Conjugate for PAC, comprises the BRD4 degrader GNE-987 and PEG-based linker.
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DC40628 | XZ739 |
XZ739, a CRBN-dependent PROTAC BCL-XL degrader with a DC50 value of 2.5 nM in MOLT-4 cells after 16 h treatment. XZ739 also induces cell death through caspase-mediated apoptosis.
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DC40608 | Bis-BCN-PEG1-diamide |
Bis-BCN-PEG1-diamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC40607 | DBCO-C2-SulfoNHS ester |
DBCO-C2-SulfoNHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC40606 | Methyltetrazine-PEG4-SSPy |
Methyltetrazine-PEG4-SSPy is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC40605 | Mal-amide-PEG2-oxyamine |
Mal-amide-PEG2-oxyamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC40604 | Bromoacetamide-PEG3-C1-acid |
Bromoacetamide-PEG3-C1-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC40603 | Methyltetrazine-PEG4-amine hydrochloride |
Methyltetrazine-PEG4-amine (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC40601 | Mal-amide-PEG2-oxyamine-Boc |
Mal-amide-PEG2-oxyamineBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC40600 | Boc-HyNic-PEG2-DBCO |
Boc-HyNic-PEG2-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC40599 | Boc-HyNic-PEG2-N3 |
Boc-HyNic-PEG2-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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