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ATX inhibitor 1

  Cat. No.:  DC39630   Featured
Chemical Structure
2225892-70-4
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More than 5000 active chemicals with high quality for research!
Field of application
ATX inhibitor 1 is a potent ATX (IC50=1.23 nM, FS-3 and 2.18 nM, bis-pNPP) inhibitor.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2225892-70-4
Chemical Name: ATX inhibitor 1
Synonyms: ATX inhibitor 1;(4-(1-(((3,5-Dichlorobenzyl)oxy)carbonyl)piperidine-4-carboxamido)benzyl)phosphonicacid;(4-(1-(((3,5-Dichlorobenzyl)oxy)carbonyl)piperidine-4-carboxamido)benzyl)phosphonic acid;[4-[[1-[(3,5-dichlorophenyl)methoxycarbonyl]piperidine-4-carbonyl]amino]phenyl]methylphosphonic acid;BDBM50458125;E74832
SMILES: ClC1C=C(C=C(C=1)COC(N1CCC(C(NC2C=CC(CP(=O)(O)O)=CC=2)=O)CC1)=O)Cl
Formula: C21H23Cl2N2O6P
M.Wt: 501.296884775162
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication: [1]. Balupuri A, et al. Discovery and optimization of ATX inhibitors via modeling, synthesis and biological evaluation. Eur J Med Chem. 2018 Mar 25;148:397-409.
Description: ATX inhibitor 1 is a potent ATX (IC50=1.23 nM, FS-3 and 2.18 nM, bis-pNPP) inhibitor.
Target: IC50: 1.23 nM (FS-3) and 2.18 nM (bis-pNPP)[1]
References: [1]. Balupuri A, et al. Discovery and optimization of ATX inhibitors via modeling, synthesis and biological evaluation. Eur J Med Chem. 2018 Mar 25;148:397-409.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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