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PfDHODH-IN-2

  Cat. No.:  DC39802   Featured
Chemical Structure
425629-94-3
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More than 5000 active chemicals with high quality for research!
Field of application
PfDHODH-IN-2, a dihydrothiophenone derivative (Compound 11), is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitor with an IC50 of 1.11 µM. PfDHODH-IN-2 acts as an antimalarial agent and can be used for the research of malaria.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 425629-94-3
Chemical Name: ethyl 2-[(4-chlorophenyl)amino]-4-oxo-4,5-dihydro-3-thiophenecarboxylate
Synonyms: ethyl 2-[(4-chlorophenyl)amino]-4-oxo-4,5-dihydro-3-thiophenecarboxylate
SMILES: CCOC(C1C(=O)CSC=1NC1=CC=C(Cl)C=C1)=O
Formula: C13H12ClNO3S
M.Wt: 297.757281303406
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication: [1]. Minghao Xu, et al. Novel selective and potent inhibitors of malaria parasite dihydroorotate dehydrogenase: discovery and optimization of dihydrothiophenone derivatives. J Med Chem. 2013 Oct 24;56(20):7911-24.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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