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BAY 2416964

  Cat. No.:  DC39022   Featured
Chemical Structure
2242464-44-2
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More than 5000 active chemicals with high quality for research!
Field of application
BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1, example 192, has an IC50 of 341 nM. BAY 2416964 has the potential for solid tumors treatment.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2242464-44-2
Chemical Name: BAY 2416964
Synonyms: BAY 2416964；BAY-2416964；BAY2416964
SMILES: O=C(N[C@H](CO)C)C1C(=O)N(C2C=NN(C)C=2)N=C(C2C=CC(Cl)=CC=2)C=1
Formula: C18H18ClN5O3
M.Wt: 387.82
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication: [1]. Ilona GUTCHER, et al. 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer. WO2018146010A1
Description: BAY 2416964 is a 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamide compound and an aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1, example 192, has an IC50 of 341 nM. AHR antagonist 3 has anti-cancer effects[1].
In Vitro: AHR antagonist 3 (Example 192) induces AHR-regulated gene CYP1A1 expression in a human monocytic U937 cells with an IC50 of 4.3 nM[1].
MSDS
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MSDS_20439_DC39022_2242464-44-2
COA
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