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Home > PROTACs > E3 Ligase Ligand

E3 Ligase Ligand 3

  Cat. No.:  DC11571   Featured
Chemical Structure
1061605-21-7
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More than 5000 active chemicals with high quality for research!
Field of application
E3 ligase Ligand 3 is a ligand of E3 ligase, used in PROTAC technology.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1061605-21-7
Chemical Name: 2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetic acid
SMILES: C(O)(=O)COC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O
Formula: C15H12N2O7
M.Wt: 332.268
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: An E3 ligase ligand for PROTAC.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC86101 VH032-cyclopropane-F E3 ligase Ligand 19 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 19 can be connected to the ligand for protein (e.g., SMARCA BD ligand) by a linker to form PROTACs (e.g., PROTAC 1). PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4[1]
DC51007 Lenalidomide-5-aminomethyl hydrochloride Lenalidomide-5-aminomethyl hydrochloride is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-5-aminomethyl hydrochloride can be connected to the ligand for protein by a linker to form PROTAC
DC51006 Lenalidomide-4-OH A Novel PROTACs building block.
DC71103 Pomalidomide-PEG4-COOH Pomalidomide-PEG4-COOH is a E3 ligase ligand-linker conjugate. Pomalidomide-PEG4-COOH contains the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology (extracted from patent WO2017184995A1).
DC47216 Thalidomide-5,6-F Thalidomide-5,6-F is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5,6-F can be connected to the ligand for protein by a linker to form PROTACs.
DC41134 Thalidomide-5-OH Thalidomide-5-OH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-OH can be connected to the ligand for protein by a linker to form PROTACs.
DC12028 MDK7526(Protein degrader 1) MDK7526, also known as VHL Ligand 1; Protein degrader 1, is a potent and selective protein degrader.
DC11571 E3 Ligase Ligand 3 E3 ligase Ligand 3 is a ligand of E3 ligase, used in PROTAC technology.
DC50061 Pomalidomide-C2-NH2(E3 ligase Ligand 17) E3 ligase Ligand 17 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 17 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
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