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Capmatinib hydrochloride

  Cat. No.:  DC60059   Featured
Chemical Structure
1865733-40-9
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More than 5000 active chemicals with high quality for research!
Field of application
Capmatinib, also known as INCB28060 and INC280, is an orally bioavailable inhibitor of the proto-oncogene c-Met with potential antineoplastic activity. c-Met inhibitor INC280 selectively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways. This may induce cell death in tumor cells overexpressing c-Met protein or expressing constitutively activated c-Met protein. Capmatinib was approved in 2020.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1865733-40-9
Chemical Name: Capmatinib hydrochloride
Synonyms: Capmatinib hydrochloride;C2A374O70X;Capmatinib dihydrochloride monohydrate;Capmatinib hydrochloride [USAN];Capmatinib hydrochloride (USAN);Capmatinib hydrochloride hydrate (JAN);D10891;Q27895918
SMILES: FC1=C(C(NC)=O)C=CC(=C1)C1C=NC2=NC=C(CC3C=CC4=C(C=CC=N4)C=3)N2N=1.Cl.Cl.O
Formula: C23H21Cl2FN6O2
M.Wt: 503.356245756149
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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